jorge_adeva_MD retweetledi
jorge_adeva_MD
1.1K posts

jorge_adeva_MD
@cofiadeva
Medical oncologist, Hospital Universitario 12 de octubre, Madrid (Spain). Focused in Biliary Tract cancer (Cholangiocarcinoma) and Hepatopancreatic cancer.
Katılım Eylül 2012
154 Takip Edilen383 Takipçiler
jorge_adeva_MD retweetledi

Prognostic Impact of Metastatic Sites in Patients with Biliary Tract Cancer Treated with Cisplatin, Gemcitabine, and Durvalumab | Targeted Oncology | Springer Nature Link link.springer.com/article/10.100…
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@ChandrakanthMv @oncology_bg Very practical and essential issue for oncologists.
However, we still need a better tool for selecting filgastrim
1. How many days
2. When to administer dedepending on chemo schedule, 1w, 2w, 3w...
3. Does oral chemo matters? Concomitant EPO?
4. Netter at night? Paracetamol ok?
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• G-CSF if FN risk ≥20%
• <20%? Only if patient high-risk
• Don’t use for afebrile neutropenia
• Not routine for FN treatment
• Curative intent? Preserve dose intensity
Use wisely. Not routinely.
#MVOnco #ASCO2026 #GCSF #FebrileNeutropenia #Oncology

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jorge_adeva_MD retweetledi

🟢 El cáncer de vías biliares es un tumor poco frecuente pero elevada mortalidad
➡️ Incidencia de 2,89 casos por 100.000 hab.
➡️ La supervivencia a 5 años apenas alcanza el 20%
👉 La inespecificidad de los síntomas y el diagnóstico tardío son los principales retos
#SomosTTD

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jorge_adeva_MD retweetledi

@cofiadeva @MacarullaTeresa @DrAngelaLamarca ➡️ Para reducir desigualdades en el acceso a la innovación, hemos impulsado TTD Trials
✅ Una herramienta que permite a cualquier oncólogo en España consultar ensayos clínicos activos y contactar con equipos especializados, facilitando la derivación y acceso a terapias avanzadas


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jorge_adeva_MD retweetledi

@cofiadeva @MacarullaTeresa @DrAngelaLamarca ➡️ Además, hemos desarrollado RETUD, un Registro de Tumores Digestivos que recopila datos clínicos y moleculares de pacientes reales
✅ Más conocimiento significa mejor diagnóstico, tratamientos más precisos y nuevas oportunidades para el futuro


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jorge_adeva_MD retweetledi

📍No te pierdas el #TTDCOLOQUIO 'HER2 en vía biliar: una nueva realidad '
📅26FEB
⏰17h
Coordina: Dr Muñoz
📢Dra @MacarullaTeresa (@hospitalclinic)
Dr @cofiadeva (HU12OCTUBRE)
us06web.zoom.us/webinar/regist…
Patrocina @JazzPharma @AstraZenecaES
👉Abierto a especialistas interesados

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@Erman_Akkus Rechallenge with CisGem Durva or Pembro. I guess Cisgem was given x 6mo, so lymph node PD was after 7 months of watch and wait? Platine sensitive concept, although ABC-06 seemed not to impact, interesting. How about AFP and Ca19-9 at PD?
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📊One-question #oncpoll
A case of "combined HCC-CCA"
➡️60y male, tumor filling the right lobe of liver, AFP: 1200, Ca19-9: 8300, CT: HCC, Biopsy: pancreaticobiliary origin?
➡️2xTACE, GemCis ➡️ PR
➡️Lymph node mets after 13mo
❓What would you offer for 2L?
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jorge_adeva_MD retweetledi

Final Results from a First-in-Human Phase I Study of the Dual IDH 1/2 Inhibitor, LY3410738, in Solid Tumors Harboring IDH1 or IDH2 Mutations
@CCR_AACR
doi.org/10.1158/1078-0…
🔎119 pts mono, 19 pts with CISGEM
👉ORR 5.2% & 11.1%
👉LY3410738 + CISGEM in BTC: ORR 42%, mPFS 8mo
🧐Could be interesting in BTC
@myESMO @EASLedu

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33rd TTD Congress! #TTD25
💼 Thank you so much for the opportunity to review a tough but very important topic for Digestive Cancer Oncologists.🎄Amazing Oviedo gathering science and friends, celebrating Christmas and a hopefully wonderful 2026 full of good news for our patients.




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jorge_adeva_MD retweetledi

"La medicina de precisión, basada en la identificación de alteraciones moleculares, es fundamental para mejorar las opciones terapéuticas"
✒️#Opinión_iSanidad de Dr. Jorge Adeva (@cofiadeva) y La Dra. @MacarullaTeresa
f.mtr.cool/fompbnxzja
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jorge_adeva_MD retweetledi

➡️Cáncer de páncreas y equidad: que el código postal no determine las oportunidades de cada paciente
Opinan los Dres. Jorge Adeva @cofiadeva y @MacarullaTeresa, coordinadores del grupo de trabajo Biliopancreático del TTD
Puedes leerlo en @isanidad⤵️
isanidad.com/351293/cancer-…
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jorge_adeva_MD retweetledi

✳️Que el código postal✖️✖️✖️✖️✖️ no determine las oportunidades de cada paciente✳️
👉Con motivo del DM de #CáncerdePáncreas, los Dres. del TTD @cofiadeva y @MacarullaTeresa opinan hoy en @elperiodico
🎯Medicina personalizada en todas las CCAAs
ℹ️elperiodico.com/es/opinion/202…

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jorge_adeva_MD retweetledi

🔥 The largest real-world cohort ever reported on chemo-immunotherapy in biliary tract cancer is now out.
👉 1358 patients treated with cisplatin/gemcitabine + durvalumab
👉 OS 15.6 months, mirroring TOPAZ-1
👉 Only 3% grade 3–4 irAEs
onlinelibrary.wiley.com/doi/10.1111/li…
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jorge_adeva_MD retweetledi

💜 November is #PancreaticCancerAwarenessMonth and #MalnutritionAwarenessWeek #ESPENMAW2025. The PANTHEIA–@_SEOM research group is working to improve outcomes by studying biomarkers and assessing nutritional risk. Grateful to all #PANTHEIA investigators, patients and @_SEOM.
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jorge_adeva_MD retweetledi

Our new study in EJC explores pathway-level genomic alterations in biliary tract cancer treated with cisplatin, gemcitabine & durvalumab.
HRD/BRCAness, TGF-β, and high TMB emerge as prognostic biomarkers.
🔗 ejcancer.com/article/S0959-…
#BTC #Cholangiocarcinoma #Immunotherapy #Oncolog
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jorge_adeva_MD retweetledi

Factors associated with reaching maintenance therapy in patients with advanced biliary tract cancer treated with durvalumab: Real-world results from a multicenter and multinational study onlinelibrary.wiley.com/doi/10.1002/ij… #hvhebron #onco
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jorge_adeva_MD retweetledi

@ZhiVenFongMD @GIMedOnc @TheNotoriousHPB @ASCO @HalletJulie @SyedAAhmad5 @NiuSanford @BasGrootKoerkam @MarcBesselink @OncoThor @ziadtawad @EileenMOReilly Does not mean we should give up and I applaud 👏🏽 all the investigators to date. We need to do these site specific biliary tract cancer trials in order to move the 🪡 forward and @cureGBC
✅ out the Gallbladder 🦀 Foundation 🪷 site:
gallbladdercancer.org
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jorge_adeva_MD retweetledi

A good read on #rarecancerday, dual #IDH1 #IDH2 inhibition in #bileductcancer #solidtumors @MSK_DeptOfMed, @AACR
aacrjournals.org/clincancerres/…
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jorge_adeva_MD retweetledi

‼️Llamamiento a #OncologosMedicos y #OtrosEspecialistas encargados de #TumoresBiliares y ejerciendo en #España
Te gustaría formar parte de una red de especialistas con tus mismos intereses?
Apúntate y te explicamos detalles 😉
docs.google.com/forms/d/e/1FAI…
🗓️11 Sept 2025
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