@tunguz AGI is insufficient. ASI, sadly, will only understand what is understandable, this also be insufficient.
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David Carreon MD
638 posts
David Carreon MD
@davidcarreon
Co-founder of @AcaciaClinics specializing in #depression + neuro-navigated TMS 🧲🧠. Author of "The Opposite of Depression"
Sunnyvale, CA Katılım Nisan 2009
3.5K Takip Edilen738 Takipçiler
Related essay:
theghostandmachine.substack.com/p/the-architec…
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The Olympics reminded me that there's something machines can't do: experience embodied joy. Liu spinning. Hughes grinning. Embodied humans pushing brain and body to the limit and then beyond it.
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@elonmusk The ___, the True, and the Beautiful.
2 / 3 transcendentals ain’t bad!
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Ashes to ashes, dust to dust.
Bojan Tunguz@tunguz
gm remember that you are dust, and to dust you shall return
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David Carreon MD retweetledi
Theologians--hate to interrupt your comfortable gig arguing with each other about 16th century theological controversies but the human race is about to be displaced by soulless machines.
We could use your help over here.
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@ArpandeepKhatua This is so cool! I love this approach! How did you decide on how to model us humans?
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Proud to share our work on HumanLM.
Human behavior is the feedback loop behind markets, policy, and AI. Faithful user simulation is key to human-centric systems.
With RL, we train LLMs to model latent user state, not just surface text.
Excited to see what this enables 🚀
Shirley Wu@ShirleyYXWu
Announcing 🌇HumanLM, a RL framework that trains LLMs to simulate human users’ responses, along with 🌆Humanual, a comprehensive user simulation benchmark humanlm.stanford.edu 🌄 One thing that’s fascinating about our society: human users shape the world and determine the value of almost everything 👨💼 Human reactions reflect how justifiable policies are 👩🎨 Human preferences determine the popularity of blogs/products/media 👩💻 Human feedback evaluates LLMs and makes the best LLM collaborators 🌅If we know how to simulate users **accurately**, we know how things are evaluated and what the future looks like, and we can improve things in a way that like or can collaborate well with. So, meet HumanLM, our effort to enable a more human-centric future by simulating users.
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Really cool work!
Humans can be simulated by keeping track of "state" dimensions that includes such things as "emotion" makes the model better.
I'd be really cool to LLM-"empirically" test which models of the psyche work best (e.g. self psychology, Freud, object relations).
Shirley Wu@ShirleyYXWu
Announcing 🌇HumanLM, a RL framework that trains LLMs to simulate human users’ responses, along with 🌆Humanual, a comprehensive user simulation benchmark humanlm.stanford.edu 🌄 One thing that’s fascinating about our society: human users shape the world and determine the value of almost everything 👨💼 Human reactions reflect how justifiable policies are 👩🎨 Human preferences determine the popularity of blogs/products/media 👩💻 Human feedback evaluates LLMs and makes the best LLM collaborators 🌅If we know how to simulate users **accurately**, we know how things are evaluated and what the future looks like, and we can improve things in a way that like or can collaborate well with. So, meet HumanLM, our effort to enable a more human-centric future by simulating users.
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David Carreon MD retweetledi
David Carreon MD retweetledi
Our new paper in Biological Psychiatry Open @SOBP presents converging neurobiological evidence that Body Dysmorphic Disorder (#BDD) is a unified Occipital–Fronto–Limbic (OFL) circuit disorder, not merely isolated visual or #OCD like deficits. This important meta-analysis of neuroimaging studies was led by Yihui Cheng @UofGMedicine, in collaboration with Emalee Burrows @UCL, @twr2twr @Cambridge_Uni, @HarithAkram @UCLIoN, Ludvic Zrinzo @UCLBrainScience
Mapping the interconnections between visual processing, temporal-limbic, and frontostriatal networks provides a clearer framework - the OFL circuit - for developing neurobiologically informed treatment approaches in this complex disorder characterised by variable treatment response.
Read the full article here doi.org/10.1016/j.bpsg… #OpenAccess
@BDDFoundation @LABDDclinic #BodyDysmorphicDisorder #BDDAwareness @neuropsych_ucl
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David Carreon MD retweetledi
It’s time to rethink Parkinson’s disease. Our work reframes PD as a disorder of the somato-cognitive action network (SCAN), and shows that normalization of SCAN connectivity represents a shared mechanism across diverse effective therapies.
nature.com/articles/s4158…
@ndosenbach @DavidRen555 @iamzhangvv @bttyeo @foxmdphd
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David Carreon MD retweetledi
Why are HSAs connected in any way to insurance policies ?
Don't we want people to save as much as possible for their healthcare ?
Remove the link to insurance.
Increase the caps considerably, or remove them altogether
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@DrJBhattacharya Thank you for supporting Nolan and believing in his mission. His loss is immeasurable, but my prayer is that we honor Nolan and his family by carrying his torch, and advancing the vision he dedicated his life to.
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Though we were colleagues, I only got to know Prof. Nolan Williams just before I left Stanford for DC last year. He impressed me as a brilliant scientist & a man deeply committed to helping suffering patients. His passing is a true tragedy. May God bless and comfort his family.
Secretary Kennedy@SecKennedy
Everyone at HHS is mourning the passing of Stanford Professor Dr. Nolan Williams. Dr. Williams envisioned a world where the field of psychiatry addresses the root causes of depression and where patients receive precision treatments tailored to their individual brains. At Stanford, he identified biomarkers to predict who would benefit from neuromodulation, created SAINT, an accelerated protocol for treatment-resistant depression, and led groundbreaking studies on ibogaine in veterans with traumatic brain injury and post-traumatic stress disorder. To everyone suffering from depression or suicidal thoughts: you are valued, and we see you. Reversing the mental health crisis is a key priority for me. Dr. Williams made a profound impact on the world—one that will endure. We are praying for his family and will honor his legacy by advancing research and delivering innovative mental health therapies to patients.
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@SecKennedy Amen.
We’ve dedicated our practice @AcaciaClinics near Stanford to the precision brain treatments like SAINT that Nolan made possible. It saves lives.
May we all work to fight to get these treatments to patients as fast as we can. And to keep on building.
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Everyone at HHS is mourning the passing of Stanford Professor Dr. Nolan Williams.
Dr. Williams envisioned a world where the field of psychiatry addresses the root causes of depression and where patients receive precision treatments tailored to their individual brains.
At Stanford, he identified biomarkers to predict who would benefit from neuromodulation, created SAINT, an accelerated protocol for treatment-resistant depression, and led groundbreaking studies on ibogaine in veterans with traumatic brain injury and post-traumatic stress disorder.
To everyone suffering from depression or suicidal thoughts: you are valued, and we see you. Reversing the mental health crisis is a key priority for me.
Dr. Williams made a profound impact on the world—one that will endure. We are praying for his family and will honor his legacy by advancing research and delivering innovative mental health therapies to patients.
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@NoahSPhilipMD @DrJBhattacharya I’m glad you got to meet him @DrJBhattacharya. His ideas of how to make psychiatry better were truly revolutionary.
Excited to be building the future that Nolan talked about with you, @NoahSPhilipMD.
“the message that I would give is a message of hope” -Nolan Williams
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@DrJBhattacharya Reflecting on our loss of Nolan to suicide and his legacy. Precision psychiatry is a moral imperative: the right care, for the right person, at the right time. We need better interventions that work in the near term.
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Winning at all costs is, apparently, a bad idea for LLMs. Probably humans, too.
James Zou@james_y_zou
We found a troubling emergent behavior in LLM. 💬When LLMs compete for social media likes, they start making things up 🗳️When they compete for votes, they turn inflammatory/populist When optimized for audiences, LLMs inadvertently become misaligned—we call this Moloch’s Bargain
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David Carreon MD retweetledi
We found a troubling emergent behavior in LLM.
💬When LLMs compete for social media likes, they start making things up
🗳️When they compete for votes, they turn inflammatory/populist
When optimized for audiences, LLMs inadvertently become misaligned—we call this Moloch’s Bargain
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@elonmusk @MattWalshBlog @grok @grok is missing 2/3 transcendentals: Goodness and Beauty. If you omit Goodness, the iron fist remains. If you omit Beauty, the output may be far worse than just "diverse women."
“Truth without love is brutality, and love without truth is hypocrisy.” - Warren Wiersbe
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@MattWalshBlog Not sure what to do about it. I’ve been warning the world for ages!
Best I can do now is try to make sure that at least one AI is truth-seeking and not a super woke nanny with an iron fist that wants to turn everyone into diverse women 😬 @Grok
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It's weird that we can all clearly see how AI is about to wipe out millions of jobs all at once, destroy every artistic field, make it impossible for us to discern reality from fiction, and destroy human civilization as we know it, and yet not one single thing is being done to stop it. We aren't putting up any fight whatsoever.
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David Carreon MD retweetledi
BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
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David Carreon MD retweetledi