David Connell

What about the other pathogens i hear you say? @alferes_de and @lifearc1 have you covered Rapid rRNA detection of H. influenzae, S. aureus, S. pneumoniae and M. catarrhalis in bronchiectasis sputum. Better than culture- the future of micro is molecular! publications.ersnet.org/content/erjor/…

New paper! Collaboration between @EMBARCnetwork and @lifearc1 shows a molecular test can sensitively and accurately detect and quantify Pseudomonas infection in bronchiectasis. The BQA was better than culture @alferes_de @beccahull_ @MereteLong @OSibila publications.ersnet.org/content/erjor/…

@ProfJDChalmers @jfdwolff I have a feline that you should take this more seriously James

@jfdwolff boom coughing purr-ulent sputum

Thats... a cat (i thought bronchiectasis had a misdiagnosis problem)

Our latest paper just out in @LancetRespirMed 10 unanswered questions about DPP1 inhibition in bronchiectasis We outline key future clinical and research questions after the approval of the first new therapy for people with bronchiectasis. Congratulations Jiahui, Chloe and @MereteLong

First patient randomized to the ESCAPE trial testing Pseudomonas eradication vs no eradication in patients with bronchiectasis. Funded by NIHR and delivered by EMBARC @TASC_TCTU @viligorska @HollyLind19 @Shoemelia @MereteLong @beccahull_ bronchiectasis.net/escape/

UCB therapeutics announces they will trial anti-IL17/IL-13 multispecific antibody therapy in bronchiectasis in 2026 The pipeline of new therapies coming into the bronchiectasis and COPD field is exciting to see and will ultimately be great for patients. ucb.com/newsroom/press…

This is, literally, the most important countdown in the world. Oil exporters in the Persian Gulf, currently unable to export their hydrocarbon bounty, are all facing a dire short-term outlook. 🧵

Super interesting! Respiratory virus co-infection is a risk factor for bacteraemic S. aureus pneumonia which is associated with increased 30-day mortality, independent of age, co-morbidity, and receipt of immunomodulatory treatments Respiratory virus co-infection is a risk factor for adverse outcomes during Staphylococcus aureus bacteraemia #IDXposts academic.oup.com/ofid/article/d…

Very proud of the brilliant Amy Gilmour our rising star presenting the PIRATE study final results Time for antiinflammatory therapies in pleural infection? #rti2026

🔥📰Rapid and reliable diagnosis of mucormycosis using colorimetric loop-mediated isothermal amplification @JClinMicro Great collaboration with @IbrahimLab3 🙏@jprattes @SarahSedik @lagrou_katrien @JeffreyJenks5 @RobinaAerts @MatthiasEgger11 journals.asm.org/doi/10.1128/jc…

DPP1, monoclonal antibodies, phages, inhaled immunoglobulin It’s very exciting to see the pipeline of new therapies in development for bronchiectasis with much more to come The next few years will be transformational for airways research #Embarc #collaboration #carpediem

Monotherapy Vs combination therapy in severe Legionella pneumonia⁉️ 🆕⚡Retrospective, observational multicenter cohort study across ICUs The 28-day mortality was not significantly different between the two groups (15.4% vs. 12.5). No significant differences were observed in invasive ventilation duration (16.5 vs. 10 days), ICU stay length (12 vs. 11.5 days), or 90-day mortality (23.1% vs. 16.25% Monotherapy, particularly with fluoroquinolones, may be an alternative to combination therapy in managing severe Legionella pneumophila pneumonia in the ICU Small study 🚫 link.springer.com/article/10.118…

Prof Sir Nicholas White contributed significant advances to the treatment of #malaria, amongst other major achievements. @thetimes has an excellent obituary (paywall) thetimes.com/uk/obituaries/…

@Shoemelia @AlibertiStefano @lucyloveslungs @CLDaleyMD @mloebinger @ProfJDChalmers @van_jakko @Nickmaskell1 @drdavidc @EvaPolverino @DebbyBogaert @RaquelAFDuarte @ChestDrDevesh @MereteLong @Lungfoundation @beatpcd @ARIRassociation @BALRcommunity @ARNS_UK @Bronch_UK @EMBARCnetwork @tmmRESPIRATORY @meetglasgow

3 Days. 4 Parts. One unmissable RTI Forum experience. The #RTI2026 final scientific programme is now available — discover what it holds for you: rti-forum.org/2026/?page_id=… Join us in person from 2-4 March in Glasgow Science Centre and connect with experts. exchange ideas that matter

The first approved treatment for bronchiectasis ever in the UK. MHRA approved brensocatib for bronchiectasis patients aged 12 and over gov.uk/government/new…

🆕⚡🔴Legionella Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality #IDXposts academic.oup.com/cid/article-ab…

🆕 The A–E Clinical Categories stratify PE using: • Symptoms • RV dysfunction • Biomarkers • Perfusion • Shock progression This aligns PE care with modern shock & heart failure thinking.

Old PE stratification mixed BP, RV strain, biomarkers, and outcomes into blunt labels. Result: • Stable-looking patients who crashed • Overtreatment of others The 2026 guideline fixes this by focusing on physiology & trajectory.

Today, we publish a new study in Lancet Psychiatry, undertaken in hospital staff experiencing intrusive memories as a consequence of trauma exposure at work, which shows that our intervention reduces intrusive memories in a sustained manner 3/4 thelancet.com/journals/lanps…