Jaime Imitola MD., FAAN

Dear friends, as the Chair of the International Society for Stem Cell Research @ISSCR Education Committee,.  I am excited to share that the ISSCR course Stem Cell Medicine: Parkinson’s Disease has just launched TODAY. invt.io/1exbt3o2p5d

Take our new, free, on-demand course, Stem Cell Medicine: Parkinson’s Disease. Explore the science behind dopamine neuron replacement, clinical trial progress & how emerging stem cell therapies compare with current treatments for Parkinson’s disease 👉 bit.ly/4mpoh0Q

Check out our @ContinuumAAN chapter on Adult-Onset Leukodystrophies Mimicking #MultipleSclerosis. Although individually rare, these disorders represent a diagnostic challenge when assessing for MS. Enjoyed working with R.LaPiana on this ! continuum.aan.com/doi/abs/10.121…

Organized by Health Equity Solutions in partnership with @UConnHDI, the upcoming Health Equity Week (April 6-11), invites people to intentionally step into their civic power and actively shape a healthier, more equitable Connecticut. today.uconn.edu/2026/04/connec…

Silva et al. show that HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) shares key inflammatory and neurodegenerative pathways with progressive MS, highlighting its value as a model of chronic inflammation-driven neurodegeneration. shorturl.at/rOcfJ

Can we trust #remote neurologic exams in 2026? Research suggests that for mild-to-moderate #MultipleSclerosis, disability #evaluation is feasible even without on-site aide. The next step is standardized training to bridge confidence gap for HCPs and PwMS. doi.org/10.7224/1537-2…

Privosegtor has received PRIME designation in Europe for the treatment of optic neuritis, a condition commonly seen in multiple sclerosis. buff.ly/yUGOAfH #MultipleSclerosis #MSTreatment #MSResearch #MSNews

"Where and how people live may be as important for brain aging as the specific disease they develop." Physical and social exposome factors associated with accelerated brain aging across 34 countries Physical factors primarily linked with structural MRI brain aging; social with functional aging @NatureMedicine

Risk of Multiple Sclerosis Among Persons With Epstein-Barr Virus–Positive Mononucleosis A Population-Based Study neurology.org/doi/10.1212/WN…

What would it look like to see all ~13,000 proteins inside a single human cell at once? We share ProtiCelli — a generative model that makes this possible. Besides benchmarking, we demonstrate utility in many tasks. Preprint: bit.ly/3NY175q A thread 🧵👇

Happy to share @andreuvilaseca7 et al collaboration with @ESotirchos on the TRUE-MOGAD Score to discriminate true & false positive MOG-IgG ➡️ We have created an online calculator for ease of use: news.mayocliniclabs.com/true-mogad-cal… The article link is below: 👇 neurology.org/doi/10.1212/NX…

Neighborhood deprivation was associated with worsening manual dexterity, walking speed and quality of life in people with #MultipleSclerosis 55 years of age and older. Study from @ClevelandClinic @CLENeurons ▶️ journals.sagepub.com/doi/abs/10.117…

@andreuvilaseca7 @MayoClinic @JohnsHopkins Thanks very helpful, there are a lot patients with low positive values that are treated as MOGAD in the absence of the additional data including in the tool. @UConnMSNews @uconnhealth

A positive MOG antibody result does not always mean MOGAD‼️ TRUE MOGAD Score helps neurologists worldwide estimate whether a positive MOG result is truly clinically meaningful. Proud collaboration between @MayoClinic and @JohnsHopkins Scan the QR code below to access the tool 👇🏽

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation | Nature nature.com/articles/s4158…

POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, M-protein and Skin changes) syndrome is a rare multisystem disorder where early identification is essential for better long term outcomes. Yet it is often misdiagnosed. Gonçalves et al review the condition here: jnnp.bmj.com/content/early/… And this is a related editorial: jnnp.bmj.com/content/early/…

Extending low-dose rituximab after at least 1 year of clinical and radiological stability in relapsing #MultipleSclerosis was not associated with an increased risk of disease activity. Study from @KPSCALnews ▶️ journals.sagepub.com/doi/abs/10.117…

Our free, on-demand Continuing Education Course, Stem Cell Medicine: From Scientific Research to Patient Care, offers expert-led lectures on stem cell biology, clinical trials, patient communication, and unproven treatments . Learn more 👉bit.ly/4mpoh0Q

Coming next week…

Nearly 1 million people in American live with a multiple sclerosis diagnosis. During MS Awareness month, meet a patient who found new hope after getting answers and help from the team at UConn Health. today.uconn.edu/2025/07/multip…

Tu paciente lleva 5 años sin brotes, sin actividad en RM, estable. ¿EMRR, SPMS no activa, o simplemente... la etiqueta ya no encaja?

 🔜 Nueva controversia en Hot Topics en EM: Cemcat Series | ¿Hay que cambiar la clasificación fenotípica de la EM del 2014? 👉 Online - Acreditada - bit.ly/HTEM2026 🗓 Miércoles 15 abril | 16:00 - 17:00h (CEST) ➡️ Inscríbete gratis: bit.ly/HTEM2026 ✅ A FAVOR: Dr. José Meca Lallana - Jefe de Sección de Neurología y Coordinador CSUR-EM, H. Virgen de la Arrixaca, Murcia. ❌ EN CONTRA: Dra. Yolanda Aladro Benito - Jefa de Sección Unidad EM, H. Universitario de Getafe, Madrid. 🗣️ Modera: Prof. Xavier Montalban - Neurólogo - Director, Profesor de Neurología - Cemcat, HUVH, UAB y UVic-UCC, Barcelona. ➡️ Más información bit.ly/HTEM2026 #HotTopics2026 #HotTopicsEM #EsclerosisMúltiple #Neurología