

Valentina Bruno
8 posts






Grateful to all who made my MSc thesis work possible! In our in-vitro model of blood outgrowth #endothelialcells, cyclosporine led to: ⬇️ #glycocalyx ⬇️ CFH binding & cofactor activity ⬆️ C3 & C5b9 deposition ⬆️ endothelial cell injury @UofTIMS @uoftmedicine @SickKidsNews


New Research: The loss of glycocalyx integrity impairs complement factor H binding and contributes to cyclosporine-induced endothelial cell injury: Background Calcineurin inhibitors (CNIs) are associated with… frontiersin.org/articles/10.33… #medicalcare #clinical #pathology












Intra-dialytic hypotension (IDH) is the most common serious adverse event in paediatric haemodialysis. Read this Original Article on implementing a PedHDfluid program using the Model for Improvement methodology aimed at decreasing IDH. link.springer.com/article/10.100…