Whoa! This looks a big breakthrough!
Cryo structures of caveolin assemblies. Are these in vitro caveolae? Thoughts from caveolae mavens @LabParton ?
biorxiv.org/content/10.110…
Students, assuming we're all doing online learning again in the fall, what do you want your profs to keep doing/stop doing/start doing? (Faculty tweeps, please RT)
"It would therefore take a heroic effort & very fast #quarantine & isolation to identify, by traditional methods, every person who’s infected, & every person they contact, & everyone they contact.”
@meyerslab on the need for distributed disease tracking:
statnews.com/2020/04/02/cor…
@UWVirology is OPEN and expanding testing (despite confusion around @nytimes article). We tested for over 900 people on 3/10 with approximately 7% positive.
Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin bit.ly/3b57H1L Robert C. Klipp, Megan M. Cullinan, and John R. Bankston
@MikePuljung Bought a Heka epc 9. The vendor (Boston Industries) had a store in ebay, and the bigger headache was getting the purchase approved since it was refurbished equipment. Almost not worth it considering the red tape I had to go through.
Fish with electric organs can distinguish whether they are near conducting materials (animals) or nonconducting (rock) using hair cell-derived cells expressing KCNA7a. From Harold Zakon. Wow.
Had a wonderful time hosting @carlson_lab at @ut_neuroscience and hear about the amazing signaling events at fertilization. Stay tuned to her lab’s research!
Bar Naked Data (not a typo): I'll be discussing data visualization for lab meeting tomorrow and using this excellent @jbiolchem paper as a guide:
jbc.org/content/292/50…
~6 yrs ago, super-res imaging by Xiaowei Zhuang’s lab revealed surprising, regularly-spaced actin rings along neuronal axons. Now, her lab makes progress figuring out what they are for: dynamically-regulated structural platforms for GPCR/CaM/RTK signaling
tinyurl.com/y232rdsq
Congratulations to @UWSoN colleagues @IraKantrowitz & Molly Altman on this important work! Pregnant women of color experience disempowerment by health care providers washington.edu/news/2019/08/2…
John Cowgill and Baron Chanda of @UWMadison discuss the importance of voltage clamp fluorometry to the functional interpretation of ion channel and transporter structures bit.ly/2ZevJQN#JGP100#ionchannels