Fred Bard
47 posts
Fred Bard
@fred_bard
Sr. Principal Investigator at Institute of Molecular and Cell Biology
Singapore Katılım Ekim 2013
115 Takip Edilen121 Takipçiler
I've just contributed to STOP Croisières. Consider supporting them too — every little helps! opencollective.com/stop-croisieres via @opencollect
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Fred Bard retweetledi
"Some observers of the Russo-Ukrainian war seem to think that its greatest danger is that Ukraine will win, or win too quickly, and that this will be uncomfortable for Putin, and that we should care. This is a deeply perverse way of seeing things."
snyder.substack.com/p/the-folly-of…
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Fred Bard retweetledi
Graduation day in Kharkiv, Ukraine
Andrei Kurkov@AKurkov
The graduates of Kharkiv School 134 still decided to take photos in front of their school that was destroyed by Russians. There are 111 schools that are completely destroyed by Russia in Ukraine. This number will grow unless Ukrainian army can stop them.
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Fred Bard retweetledi
Nos dirigeants répètent en boucle que l’Histoire est redevenue tragique. Mais quand agiront-ils en conséquence? Ont-ils vraiment compris que l’avenir de l’Europe se décidait dans les ruines de Marioupol et les rues de Kyiv?
Le Monde@lemondefr
TRIBUNE | @rglucks1 « Si nous ne défendons pas l’Ukraine pour nos principes, alors faisons-le pour nos intérêts vitaux » #Echobox=1647334490" target="_blank" rel="nofollow noopener">lemonde.fr/idees/article/…
Français
Russian dolls, multiscale project: study protein glycosylation in the Golgi of a cancer cell in an organoid injected in an organ.
euraxess.ec.europa.eu/jobs/717342
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Sea, Sun and Science in Marseille: a postdoc position opened in my new lab!
euraxess.ec.europa.eu/jobs/717342
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You can now read about the "Kiss of Src" at: elifesciences.org/articles/68678
How Src does it to GBF1 and how it makes it leave the Golgi, taking the tubular car, Arf1 and the GALNTs with it ... PG13 for scenes of extensive phosphorylation!
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Fred Bard retweetledi
What an amazing story that is out today; both, the publication and the making of! Great that we could contribute to this project.@reversade @fred_bard @Holab_DukeNUS @MaurerStroh Congratulations 🥳 Hui Hui. authors.elsevier.com/c/1d7lbgeW~iUL…
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@GDarmanin En 1956, les ecoles primaires abolissaient le vin à la cantine. En 2021, il est temps d’arrêter la viande. Pour le futur de tous; ce n'est pas de l’idéologie, c'est du réalisme: on ne va pas contenir le réchauffement sans faire de sacrifice.
Français
En plus de l’insulte inacceptable aux agriculteurs et aux bouchers français, on voit bien que la politique moraliste et élitiste des « Verts » exclut les classes populaires. De nombreux enfants n’ont souvent que la cantine pour manger de la viande... Idéologie scandaleuse.
BFM@BFMTV
Les écologistes imposent temporairement un menu unique sans viande dans les cantines scolaires à Lyon bfmtv.com/lyon/a-lyon-le…
Français
Indeed! The textbook models of vesicular traffic appear less and less phased with reality.
Francesca Bottanelli@Fran_Bottanelli
Nice to see how ARF1 function in the formation of tubules we described back in 2017 pubmed.ncbi.nlm.nih.gov/28428254/ is regulated! but maaan this COPI results leaves me baffled...
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Fred Bard retweetledi
Nice to see how ARF1 function in the formation of tubules we described back in 2017 pubmed.ncbi.nlm.nih.gov/28428254/ is regulated! but maaan this COPI results leaves me baffled...
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Thanks Fran! Very kind of you. Really liked your 2017 paper too.
Francesca Bottanelli@Fran_Bottanelli
Interesting from @fred_bard! Src phosphorilates the GEF GBF1 which activates ARF1 for tubules formation while COPI vesicle formation is unaffected!
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Beautiful modelization. Glycosylation changes with age, it is also variable between individuals. Could it explain some of the differences in severity observed among patients?
Oliver Grant@Olivercgrant
Glycosylated SARS-Cov-2 Spike Trimer. Biantennary LacNAc N-glycans (18 per protomer) are shown in dark magenta. Protein is from Swiss-Model (based on 6VSB), glycans built using glycam.org. #glycotime #COVIDー19 @SWISS_MODEL @glycam
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@Olivercgrant @SWISS_MODEL @glycam Beautiful re-construction. Interesting to think that glycosylation patterns change a lot with age, they also vary between individuals. Could these patterns explain some of the stark differences that are observed between patients?
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Glycosylated SARS-Cov-2 Spike Trimer. Biantennary LacNAc N-glycans (18 per protomer) are shown in dark magenta. Protein is from Swiss-Model (based on 6VSB), glycans built using glycam.org. #glycotime #COVIDー19 @SWISS_MODEL @glycam
GIF
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#Covid_19fr
Herd immunity: 20th century
Testing, tracking and isolating: 21st century
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