Fred Howard

Dr. @fredhow and colleagues from across the globe have a new article out in @AACR's Clinical Cancer Research: aacrjournals.org/clincancerres/… Read on to learn how they've used machine learning to better predict recurrence risk and treatment efficacy!

🚨 New article alert!! 🚨 A great new piece in @Annals_Oncology about the benefits of anthracyclines in certain types of #BreastCancer: annalsofoncology.org/article/S0923-… from Drs. @fredhow, @MsNanchen, & others! @UCCancerCenter // @UChicagoMed

In a new commentary Freeman et al. points out that patients with ER-low tumors may not benefit from estrogen therapy in adjuvant setting, suggesting re-evaluation of systemic treatment strategies. @UChicagoHemOnc @RitaNandaMD @fredhow @uchicago_obgyn ow.ly/Leto50WObj7

🔥Hot off the press: In a new study, @UChicagoMed’s researchers found that triple-negative breast cancer patients with lower socioeconomic status have less access to life-saving treatments. @JAMANetworkOpen @fredhow @spshubeck @UChicagoHemOnc @UChicagoPHS ow.ly/hl4T50V1qkZ

2 important articles in the @JCO_ASCO Top Articles of 2024: ascopubs.org/doi/10.1200/CC… in @JCOCCI_ASCO by Dr. @fredhow, Dr. Pearson, Anran Li, & colleagues and ascopubs.org/doi/10.1200/OA… in JCO Oncology Advances by Drs. Huo, @RitaNandaMD, @MsNanchen, @fredhow from Hem/Onc & colleagues!

Jazzed to see our work describing *potential LLM use trends in @ASCO abstracts* as one of the @JCO_ASCO family top articles of 2024. Check out all the top articles here: ascopubs.org/2024-top-artic…. @fredhow @LGM_Biostats @JCOCCI_ASCO @UCCancerCenter @UChicagoBSD

Congratulations to @NUCATSInstitute member @CatGaoHow, who has been named Associate Director of @IAIM_NU 's Center for Collaborative AI in Healthcare. A physician-scientist, Gao’s research focuses on leveraging machine learning to enhance ICU patient care bit.ly/3NOlfmG

So honored and grateful for this! Thanks to all the mentors and team members who have supported me. 💖 Looking forward to exciting new work together with @IAIM_NU @IPHAM_CHIP @NM_Lung @NUFeinbergMed and many others!

Exciting work in @Nature_NPJ from @UChiPritzker's Asim Dhungana - predicting recurrence from quantitative IHC using #machinelearning, prognostic in Oncotype high/low risk cases, calculator at rsncdb.cri.uchicago.edu @UCCancerCenter @UChicagoBreast #bcsm doi.org/10.1038/s41523…

‼️ #ASCO24 simultaneous publication by @lab_pearson et al: Characterizing the Increase in Artificial Intelligence Content Detection in Oncology Scientific Abstracts from 2021 to 2023: ➡️brnw.ch/21wKljc

@fredhow presents an excellent poster at #ASCO24 showing increased use of ChatGPT in generating scientific abstracts directed towards need to bring new policies. @Lab_Pearson @UCCancerCenter @UChicagoHemOnc

@UChiPritzker @fredhow @ASCO @LGM_Biostats @OpenAI @jcocci_asco will publish @fredhow @LGM_Biostats work "Characterizing the Increase in Artificial Intelligence Content Detection in Oncology Scientific Abstracts from 2021 to 2023" and #JCOCCI EIC Dr. Jeremy Warner to discuss live. 📍June 2, 10:00AM S403B. (Journals Lounge) (4/n)

Excited to share our study of RSClin in 280k pts doi.org/10.1002/cncr.3… In the lowest risk pts per RSClin-no chemo benefit even if Oncotype high. For high risk-question of OFS vs chemo remains (I vote OFS) Congrats Augustin! @GenomicHealth @folopade @RitaNandaMD @UChicagoBreast

Absolutely outstanding discussion of AI based predictors specifically around lobular breast cancer by @fredhow @UChicagoMed following amazing work by @FresiaPareja in the Reis Filho lab

Augustin Vannier discusses the data in today’s poster session at #ASCO23. He explains the utilization of genomic data to identify the patients that benefit from chemotherapy treatment. @fredhow @UCCancerCenter @UChicagoMed @UChicagoHemOnc

Our latest paper, "Deep learning generates synthetic cancer histology for explainability and education", is out! nature.com/articles/s4169…. We use #digitalpathology AI for 🧪 scientific discovery & 🏫 education by enabling deep neural networks to "teach back" what they learn. (1/5)

Overjoyed to see CarpeDiem out in @jclinicalinvest! We used #machinelearning to examine unresolving pneumonia here: jci.org/articles/view/… @NM_Lung @NUFeinbergMed @NIAIDNews @nsmarkov @macwalterMD @RoganAGrant @lrasmus @yuanhypnosluo @ScottBudinger @Misharin_lab @bsinger007

Validating a low-cost, open-source, locally manufactured workstation and computational pipeline for automated histopathology evaluation using deep learning biorxiv.org/cgi/content/sh… #bioRxiv

Topical content... Blinded human reviewers only detected 68% of #ChatGPT generated scientific abstracts, despite incorrectly identifying 14% of real abstracts as being generated. nature.com/articles/s4174…

In an analysis of over one million pts with #breastcancer, HER2-low status had minimal impact on breast cancer survival & chemotherapy response when compared to HER2-0 disease in an analysis prior to introduction of potent antibody-drug conjugates. ja.ma/3KPOtzT #BCSM