Fred Wu, MD 🫀 吳明杰

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Fred Wu, MD 🫀 吳明杰

Fred Wu, MD 🫀 吳明杰

@FredWuMD

I take care of adolescents & adults with congenital heart disease. #MedPeds #ACHD @BostonChildrens @BrighamWomens. Clinics in Boston, Providence, & Lebanon, NH.

Boston, MA Katılım Kasım 2014
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Fred Wu, MD 🫀 吳明杰
Serious question for #medtwitter: If you show up at a code, and the patient is a centaur who had a cardiac arrest, ignoring the joules question, where do you think the defib pads should go? A, assuming the heart is in the human part, or B, assuming the heart is in the horse part?
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Int’l Society for Adult Congenital Heart Disease🌎
Do you know someone with exceptional career-long dedication to #ACHD who has made a significant impact in the field? If you’re an #ISACHD member please send your nomination packet to the ISACHD Executive Committee at info@isachd.org  📅 Deadline: May 15 2026 @interactiveachd @ACHDatStanford @TorontoACHD @ACHD_CHI @achdmexico @AchdWg @mghachd @BCstyling @SAHeart_ZA
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Boston Adult Congenital Heart Program
Released today! The 2025 ACC/AHA Guideline for the Management of Adults With Congenital Heart Disease, chaired by Boston Children's Hospital #ACHD cardiologist, Dr. Michelle Gurvitz, provides updated, evidence-based recommendations across the growing and diverse ACHD population.
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Boston Adult Congenital Heart Program
♫ They're shipping up to Boston! ♫ We're so excited to welcome our newest #ACHD fellows to the Boston family! 🥼 Dr. Donnchadh (Donny) O’Sullivan from Houston 🥼 Dr. Edward (Ned) Hardison from Salt Lake City! ♫ So good! So good! ♫ @DonnchadhOSull @nedhardison
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Ryder 🇮🇪 🇪🇺
Ryder 🇮🇪 🇪🇺@Ryder56004614·
This is absolutely historic. Unbelievable. Listen to what this president say. I honestly think this press meeting is the end of him.
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Fred Wu, MD 🫀 吳明杰
Dr. Gruschen Veldtman: heart failure with or without ventricular dysfunction is far more common in #CHD and is influenced by the coronary microcirculation which suggests several potential therapeutic avenues in additional to lifestyle measures. #AHA25
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Fred Wu, MD 🫀 吳明杰
Prof. Filippo Crea on different endotypes of ANOCA (Angina with No Obstructive Coronary Arteries): ✅Epicardial spasm ✅Microvascular spasm ✅Impaired microvascular dilation during adenosine ✅Now even more identified Cardiac catheterization is best test for suspected ANOCA.
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Dr. Seda Tierney on non-invasive tools for testing for vascular dysfunction: ✅Flow-mediated dilation ✅Endothelial pulse amplitude testing ✅Pulse wave analysis ✅Arterial tonometry ✅Pulse wave velocity by echo ✅Aortic root stiffness by echo ✅Carotid intima-media thickness
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Lots of great #CHD science on the last day of #AHA25! Dr. Holly Bowser Heaton kicks off the session on coronary microvascular dysfunction. In #CHD may be due to: ✅structural vascular abnormalities ✅perivascular fibrosis ✅capillary rarefaction ✅vascular changes in cyanotic CHD
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Dr. David Goldberg talks about medical therapy to make the healthy Fontan healthier, focusing on the potential role of PDE5 inhibitors. FUEL study (udenafil) failed to meet primary endpoint of improved VO2 max, follow-up study is ongoing in pts with reduced baseline VO2. #AHA25
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The patient perspective: The way FALD is communicated to pts is very important. FALD is inherent to Fontan and not something that pts have done wrong. Despite FALD, people can enjoy a very normal life and we have to contextualize to pts and families that we are still learning.
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What can be done now to optimize liver health? Exercise and other lifestyle management incl. avoiding hepatotoxins such as alcohol, potential pharmaceutical interventions (PDE5 inhibitor?), optimize the Fontan circulation!
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Dr. Taylor Houlihan on optimizing liver function in the Fontan. Questions remain in regard to surveillance: How frequently should we screen? What are reliable lab markers and imaging grading scales for FALD? Is there a role for surveillance biopsy? #AHA25
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Dr. Christian Kreutzer on optimizing the anatomy for Fontan. Every imperfection adds to resistance and jeopardizes the future of the Fontan circulation. When it comes to anatomy we need to strive for perfection. #AHA25
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Fred Wu, MD 🫀 吳明杰
Integration of mental health professionals and/or programs in Fontan care to build resiliency and support mental health at an early age may help to sustain mental health in these individuals.
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Fred Wu, MD 🫀 吳明杰
In the “Super Fontan” session: Dr. Amanda McCormick on Sustaining Mental Health While Aging Gracefully. The burden of mental health conditions is high with 5x increased risk of anxiety, 6x increased risk of depression, and 65% lifetime prevalence of a psychiatric disorder. #AHA25
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