Guillaume Brard

@bryan_johnson Can't understand your protocols. One day you love Tixel, another day it's Fraxel. Or it's CoolPeel. Or SoftWave. Or Everesse. I mean, can you explain where you were, where you are and where you're going to on these technologies?

Results from my Feb 23 skin therapy: Improvements since treatment: > Brown spots: +71 percentile points (20th → 91st) ✅ > Pores: +25 percentile points ✅ > Spots: +25 percentile points✅ My skin age is 9 years younger than my chronological age (39 vs 48) and hasn't aged in five years since starting this project. Effectively a 9 year age reversal. Measured using VISIA multispectral clinical imaging, the most validated non-invasive skin analysis system available. Feb 23 treatment summary Technologies > Everesse RF > CoolPeel CO2 laser > BBL Each targeting a different skin depth so repair windows overlap without competing. Treatment details Everesse RF (200 pulses, Level 2.5 per cheek), CoolPeel CO2 laser (3.0W, 700 micron spacing), and BBL broadband light. Each targeting a different skin depth. Everesse drives heat into the dermis at 60-70°C, triggering fibroblast activation and collagen production that peaks 6-8 weeks later (about now), tightening the structural scaffolding that makes pores visible. CoolPeel ablates the surface layer of skin, physically removing melanin-loaded cells and forcing fresh keratinocytes to the surface. BBL destroys residual pigment one layer deeper through selective photothermolysis, where melanin absorbs light energy and self-destructs. Porphyrins dropped 13 points, which is expected. The treatments temporarily disrupt the follicular environment that bacteria need to thrive, and that recovers within 8-12 weeks. Goal was to do a triple-modality stack so the repair windows overlap without competing (dermis, epidermis, and chromophores).

@bryan_johnson The most impressive is not your RHR, it’s that your stress level for the 4 hours before bed is basically at your nighttime level.

my resting heart rate before bed last night was 41 bpm. 99.8th percentile of 18 yr olds. as a result, my sleep was perfect. zero sleep stress. no wake events. deep, restorative sleep. my body and mind cleaned itself and rebuilt. i feel amazing today. rhr before bed is a look into your soul. i've built my life around it. your rhr before bed captures and confesses levels of stress, relationship with food, wind down routine, screen usage, emotional health, cardiovascular health, sleep hygiene, circadian rhythm strength and more. lowering your rhr before bed is the number one thing you can do for your health. it's the things i've been telling you for years now: 1. final food 4 hr before bed 2. screens off 30 min before bed 3. avoid blue light 2hr before bed, use red/amber 4. book in hand 10 min before sleep 5. go to bed same time every night 6. light in eyes when waking (sun or 10k lux) 7. walk for 10 min immediately following eating 8. daily exercise (even if for 20 min) 9. eat good stuff, ditch the junk 10. foster friends, family and love

@bryan_johnson Shouldn’t you use a Hilo band to track BP continuously? May give valuable insights that are difficult to track with standard cuffs.

3/ Is this just a temporary short-lived effect of my morning routine? Or does it reflect my baseline at rest reverting to a biologically younger new normal? To answer this I am measuring my blood pressure and central pulse markers several times a day After waking up At the end of my morning routine 1 and 3 hours after my morning routine. At bedtime. This will allow me to determine the durability of these remarkable improvements and how much they reflect genuine  biological rejuvenation of my cardiovascular system.

My morning routine temporarily improves vascular function to elite teenage levels. Augmentation index: AIx of -5% AP pressure: of -1 mmHg Systolic: 87 mmHg, Diastolic: 49 mmHg. Better than >90% to healthy males in their teens.🧵

@bp_blueprint I think you should pay a 15$/hour free-lancer to align protocol between blueprint website and social medias.

what do you think? would you do this protocol?

anti-aging expert Bryan Johnson stops eating at midday. here's everything he eats in a day... 👇

@siimland Just curious, what’s the cost of a blood panel that has 183 biomarkers?

I analyzed Bryan Johnson’s biomarkers… and he doesn’t have the best in the world. I analyzed 65 of the markers he’s published: -44 of them I have better results -9 of them, Bryan has better results -12 of them are equal In this thread, I’m sharing the markers and comparing them⬇️⬇️ P.S. 1. I’m not claiming I'm the healthiest person alive or to have the world’s best biomarkers—but I do have factually better biomarkers than Bryan. There are dozens of people who have better biomarkers than Bryan and me out there. 2. This isn’t about “dunking” on Bryan. Bryan always asks for people to challenge his results and prove if someone has better markers, so here I am. 3. I disagree that you can base someone's health solely on biomarkers because biomarkers can be gamed with pharmaceuticals, etc. But I'm just playing Bryan's own game here. 4. Age is a moot point. Bryan says he has the best biomarkers of anyone in the world. If chronological age mattered, the “healthiest person” would always be an 18–20-year-old. I’m 30, and my biomarkers are better than his, so his claim doesn’t hold. He could argue he’s the healthiest 47-year-old, but not the healthiest overall. Now that this is out of the way, let's go through all the biomarkers.

@bryan_johnson So french wine is the safest drink 😀

Glass had 5 – 50× higher plastic than plastic or cans The French tested water, soda, beer, iced tea, lemonade, and wine sold nationwide and found that glass-bottled beverages carried far more plastic shrapnel than plastic bottles or cans. 🧵

@siimland Life expectancy at birth vs. sleep data probably calculated on an average population, which is quite skewed toward older ages in Japan (and older people sleep less). Might be part of the explanation, though biological / lifestyle specificities have a role too.

Japan has the 2nd highest life expectancy in the world (85.27), but they sleep on average 5.9 hours per night Very interesting. Probably due to their healthier diet and lower inflammation (inflammation increases sleep demands)

@reallyoptimized @bryan_johnson @theliverdoc Latest COA, dated March 27th, show adequate level of everything listed in supplement list. B12 levels looks fine. I’m a bit concerned about some that have higher amounts compared to what’s listed in the product description, but I feel that it may be an issue with all supplements.

It is terrifying that people do not see Bryan Johnson as actually a well-evolved masculine form of fraudsters Elizabeth Holmes and Belle Gibson, selling both expensive and utterly useless investigations and peddling potentially dangerous snake oil supplements in the name of BLUEPRINT. The only difference: Elizabeth Holmes defrauded and took rich investors money, but this gentleman is swindling poorly informed health and science Illiterates. While Belle Gibson told people she was dying, this gentleman is telling people he won't die and created a cult around not dying. She was lying and he is too.

@visionhealer @paulsaladinomd @bryan_johnson Blueprint supplements

@paulsaladinomd @bryan_johnson where does his vitamin d and b-12 come from? also plants?

I am 47 and have ideal levels of testosterone (735 ng/dL). I am not on TRT. My LH (9.7 IU/L) and FSH (7.4 mIU/ml) are also ideal. Evidence that I am not on TRT. These testosterone, LH and FSH measurements were taken 60 days ago, in Jan of 2025. My protocol: + I consume daily Blueprint proteins, supplements, longevity mix, collagen peptides, extra virgin olive oil, match, cocoa, creatine, blueberry nut mix and other Blueprint products.  + caloric restricted (2250) + plant based (excluding collagen peptides) + 130 grams of protein a day + and maintain top 1% muscle mass, cardiovascular ability, night time erections, and bone mineral density. It’s pretty cool to follow scientific evidence and measure yourself extensively. My LH (9.7 IU/L) and FSH (7.4 mIU/mL) levels confirm that I’m not on testosterone replacement therapy (TRT) because they’re ideal. Showing that my brain is actively signaling my testes to produce testosterone and sperm. If I were on TRT, the exogenous testosterone would suppress this signaling through negative feedback, and my LH and FSH would be extremely low or even undetectable. The fact that my levels are not suppressed, but instead ideal, strongly support that my testosterone is being produced naturally by my own body.

@WheyPeat @bryan_johnson @VincenzoPala I remember that a long time ago, like 2-3 years, he mentioned several times in YT videos that he has hypothyroidism since like 18 years old.

@DrBullshitMD @bryan_johnson @AdnanBoz @askgrok How much leucine in pea protein compared to beef?

@bryan_johnson Doesn’t it cause a lot of oxidative stress?

In each cylinder, the oxygen at 2100 psi weighs 45 lbs and has 3.91 × 10²⁶ oxygen molecules. I’ll inhale it in 4 hours time.

@neinneinstein @bryan_johnson Whoop

@bryan_johnson The Second app is the aura ring right?

Last night was a perfect night's sleep: + asleep in minutes + 2hr REM and 2 hr Deep + no wake events + flatlined stress score + first REM in 90 min + out of bed <1 min It feels amazing. You can get here too. It requires building your life around sleep. It's worth it.