Gil Bub

Tom Bury's (@ThomasMBury) paper in Nature Communications is out: nature.com/articles/s4146…

Very cool indeed! It was great to be part of this effort. Thank you @victor__badillo and all the other co-authors 🎉

Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology in JBO - work by postdoc Yuli Heinson and PhD student Julie Han. One of two technology development papers. Highlighted by SPIE spiedigitallibrary.org/journals/journ…

@SHWeinbergLab thanks Seth!

@gilbublab Congrats! Really nice study

Our article on parasystole is now out in PRL, with a APS news commentary by Phillip Ball. Congats to Khady, Tom, Leon and the rest of the team! News: physics.aps.org/articles/v16/2 Article: journals.aps.org/prl/abstract/1…

@blarodlo13 Thanks Blanca, looking forward to seeing you there!

And an optical mapping paper with Yuli Heinson and Julie Han - Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology biorxiv.org/content/10.110… (there is a companion ms to be deposited).

Yet another cool paper by Leonardo's group: Fast Optical Investigation of Cardiac Electrophysiology by Parallel Detection in Multiwell Plates ncbi.nlm.nih.gov/pmc/articles/P…

A #fluorescent #heart drawn by a #magnetically-guided #spheroid

We present rapid projection imaging under variable viewing angles. We apply this method in light-sheet and spinning disk microscopy to visualize 3D samples in real time. We further demonstrate that 3D information can be gathered from a set of projections. nature.com/articles/s4159…

ChR2 cell spheroids were manufactured, cryopreserved, thawed and successfully deployed for cardiac pacing; integration was faster than it takes to genetically modify the cardiac cells.

Join us on Thursday 17 June, 6-7pm to hear from @GaryMirams. His lecture on Mathematical Matters of the Heart will explain how simulations are assessing the safety of new medicines. Open to all, booking required. …ipubliclecturejune21.eventbrite.co.uk

New paper on Jakub Tomek's COSMAS data processing tools now out in Scientific Reports: nature.com/articles/s4159…

@Maurice_Y_Lee Alternative implementations are available! At @UniofExeter we replace the reflector with a smaller transmissive lens to study the feeding habits of sea worm larvae (different food stock in each well). Credit: @MarInvMet and BSc student Natalie Wood.

Sorcery!

Are you struggling to image multiple samples at the same time? A new high-throughput imaging system allows parallel imaging in a 96-well plate! Which dynamic process would you image? elifesciences.org/articles/56426…

Our Random Access Parallel ('RAP', previously 'ssHTS') #microscopy paper is out in elife: #content" target="_blank" rel="nofollow noopener">elifesciences.org/articles/56426… (@McGillPhysioloG, @alexdcorbett, @SharikaMohanan) RAP in action with a c-elegans prep:

Most imaging objectives try to minimise chromatic aberration. In this paper we exploit it to provide wavelength-dependent refocusing of brightfield images. DOI: 10.7554/eLife.56426

Creative new random access #microscopy from @gilbublab - high throughput, fast, no moving parts, using a reflector ala Newtonian telescope, #LED addressing, single camera, <$5000, #cardiac, C. elegance #imaging #content" target="_blank" rel="nofollow noopener">elifesciences.org/articles/56426…

It was fun working on this review with Matt @mwkaylab, covering the opportunities #optogenetics has brought to the #heart since 2010, when first used by @huiskenlab, P. Sasse, T. Bruegmann, O. Abilez, D. Pijnappels and several other labs including mine.