Michael Heltzen

As part of @Nasdaq's 'Amplify Spotlight' series, CEO of eXoZymes, Michael Heltzen (@heltzen), recently sat down with Michael B. Spector (@michaelbspector) from Nasdaq for a in-depth interview. Heltzen states: "That's how we can run these simulations much much faster and much cheaper than anyone else and therefore it allows us to to brute force evolution." Full interview available here: exozymes.com/blog/nasdaq-in… $EXOZ @NasdaqExchange #exozymes #exozyme #enzymes #enzyme

Advancing commercial readiness with profound production metrics on initial NCT pilot run: The pilot run achieved approximately 99% reaction conversion, 90% isolated yield, and 535 grams of NCT at 99.6% pharma-grade purity at 100L scale. Co-founder of @eXoZymes and VP of Development, Paul Opgenorth (@popgenorth), PhD, states: “What makes this initial NCT pilot run profound is how counter to conventional experience these results are. In most biological systems, performance typically degrades as you scale - reactions become harder to control, yields drop, and variability increases. With our AI-enhanced enzymes - exozymes - we see the opposite trend.” Full story here: na2.hubs.ly/H03l_W90 #exozymes #enzymes #nutraceuticals #exozyme #biomanufacturing #enzyme

It's time for another Heltzen's Video Highlight: 2025 in Review and Looking Ahead! In this video, I'm having conversations with our CSO, Tyler, and our CCO, Damien, about what happened last year and what we anticipate happening this year. Full video available here: na2.hubs.ly/H02S7b90

Here's another video update about what's going on at eXozymes, as seen from my perspective. The most important takeaway this month, is that we have the Q3 earnings call coming up this Thursday - you can sign up for that right here: exozymes.com/blog/announce-… #exozymes #exozyme #enzymes #enzyme #biomanufacturing #biosolutions

Good things are in motion. Our CEO @heltzen being interviewed by @michaelbspector at @Nasdaq today. $EXOZ

Recently, during the 'AI - A tool U.S. industrial biomanufacturing cannot ignore' panel discussion at the @Bio_Markets Innovations Midwest conference in Omaha, Nebraska, @eXoZymes VP of Business Development, Zachary Karl, PhD, stated: "I feel we have a significant opportunity to create a system where scientists are supported by AI-enabled tools. I don't think AI is going to replace the scientists in this space - I think it's going to amplify what they can do." Watch the entire World Bio Markets panel here: hubs.la/Q03MSpNc0 #enzymes #exozymes #alphafold #LLM #AI #ML #artificialintelligence

RT @eXoZymes: Inside Biotech podcast interviews CEO, Michael @heltzen: "It's very much our capabilities to pick the right enzymes and get…

Driving the cell-free revolution: @eXoZymes leaders join @TheBioMADE Leadership & Technical Committees. This underscores eXoZymes’ commitment to - and growing influence as a thought leader in - cell-free biomanufacturing. Chief Commercial Officer at eXoZymes, Damien Perriman (@Perriman), states, "Being elected to the BioMADE Leadership Council is both an honor and a responsibility. This is a pivotal moment where cell-free biomanufacturing is stepping into the national spotlight. At eXoZymes, we believe our technology will be instrumental in driving the shift toward faster, more scalable, and more resilient biomanufacturing. I look forward to working with fellow council members to shape priorities that unlock real-world impact across industries - from fuels to functional ingredients.” Co-founder and VP of Development, Dr. Paul Opgenorth (@popgenorth), states, “The Technical Committee is where the details of innovation become the standards that move an industry forward. I’m excited to play a role in defining a technical roadmap for developing and deploying cell-free enzyme pathways in the real world that can accelerate biosolution development cycles, remove the cell-based bottlenecks, and make a new generation of highly valuable natural product molecules commercially viable at scale.” Full story here: hubs.la/Q03LB2sg0 #enzyme #syntheticbiology #biomanufacturing #biosolution #exozyme #cellfree #exozymes #enzymes #synbio

This is a new format where I want to - via video - communicate about what's going on in and around @eXoZymes: Communicate with you about what's going on over the last month, what are the things that are on my mind - and our team's mind - in regards to how we're making progress. Other than news, I also want to do deeper dives into specific topics. I am super passionate about things like leadership principles, how you build a team of people that are both as individuals - but definitely also as a group - performing the very best. Please stay tuned around once per month - and feel free to ask questions! #exozymes #exozymes #enzymes #enzymes #biomanufacturing #synbio $EXOZ

“Some of the challenges in SynBio, are the costs and the timelines. Timeline-wise, it takes a while to engineer, as the DBTL (design-build-test-learn) cycles can be anywhere from months to years. And I've seen that firsthand as I was in that industry for years and years.“ - states VP of Business Development at eXoZymes, Zachary Karl, PhD, highlighting some of the challenges of the synthetic biology space - and why he jumped at the opportunity to join eXoZymes, back in September of 2023. exozymes.com/blog/challenge… #exozymes #exozyme #enzymes #enzyme #synbio #syntheticbiology #biomanufacturing #BioInnovationsMidwest #BIMW25 $EXOZ

A big shout out to the @MDBCapital team! Your conference in Dallas, Texas was nothing less than amazing. We had such a good time being in front of all the great investors, many of them that supported @eXoZymes from the beginning of the IPO and all the way forward to now. #exozymes #exozyme #enzymes #enzyme #cellfree

We're excited to announce that @eXoZymes will be presenting at the H.C. Wainwright 27th Annual Global Investment Conference in NYC, September 8–10. Join CEO Michael @Heltzen on September 9th at 8:30 AM EST in the Stanford room on the 4th floor, where he will be presenting how we're using the power of enzymes and AI to revolutionize biomanufacturing. If you're interested in having a 1:1 meeting, please email ir@exozymes.com - the schedule is filling up, quickly. Hope to see you there! #enzymes #enzyme #exozymes #exozymes #investor #investors #investorrelations

Exactly, @francesarnold @jsunn_y @francescazfl @Yueming_Long_ 👌 Obtaining a substantial amount of high-signal-to-noise enzyme data to train the proposed enzyme LLM will be crucial for such a 'Human Genome Project' for enzymes… Sounds like a big bold @DARPA, @mkoeris 😎

“Producing 4 grams of NCT at a purity higher than 99% is the kind of validation a novel platform like ours needs, to demonstrate the immense potential. Compared to extracting this from natural resources, which is the current way, you would need tens of kilograms of hemp seeds to produce the same quantity and then you’d have the headache of extracting it. That’s obviously neither an effective nor sustainable approach, which is why our exozyme biosolutions are the perfect way forward - both for NCT as well as other naturally sourced compounds.” - states co-founder and VP of Research at @eXoZymes, Dr. Tyler Korman (@tylerkorman] 📽️ Full story here: exozymes.com/blog/nct-break… 👉 Early access partnerships now open: exozymes.com/partners #exozymes #exozyme #Enzyme #Enzymes #Biomanufacturing #SyntheticBiology #SynBio #Nutraceutical #Nutraceuticals #Pharmaceuticals #Supplements #DietarySupplements #Prebiotics #FunctionalIngredients #Nutrition #NCT #NTransCaffeoyltyramine #DigestiveHealth #GutBarrierFunction #HealthyLiverFatMetabolism #MitochondrialActivity #Mitochondrial #IrritableBowelSyndrome #biosolution #biosolutions $EXOZ

🔬 Biomanufacturing breakthrough detailed: 4 grams of NCT produced at a 96% yield and with a purity higher than 99% 💥 Chief Commercial Officer at @eXoZymes, Damien @Perriman, states: "The beauty of leading with NCT as our first push to market, is that the compound has already been self-affirmed in the market as generally recognized as safe (GRAS) for functional foods. Additionally, it has multiple potential applications across different verticals in prebiotics, dietary supplements, and pharmaceuticals. We’re ramping up NCT production scale 100X over the next six months to both deliver samples to our partners as well as prepare for tech transfer to GMP pilot scale production next year. We are ready to start partner discussions for kilogram demand in 2026 and beyond that - ton scale.” 📽️ Full story here: exozymes.com/blog/nct-break… 👉 Early access partnerships now open: exozymes.com/partners #exozymes #exozyme #Enzyme #Enzymes #Biomanufacturing #SyntheticBiology #SynBio #Nutraceutical #Nutraceuticals #Pharmaceuticals #Supplements #DietarySupplements #Prebiotics #FunctionalIngredients #Nutrition #NCT #NTransCaffeoyltyramine #DigestiveHealth #GutBarrierFunction #HealthyLiverFatMetabolism #MitochondrialActivity #Mitochondrial #IrritableBowelSyndrome #biosolution #biosolutions $EXOZ

Recently, during the "AI and Machine Learning - The Silver Bullet we Must Not Dodge" panel discussion at the World Bio Markets (@Bio_Markets) conference in The Hague, CCO of @eXoZymes, Damien @Perriman, stated: "AI is about speed and quality. It is driving experiments to be faster and cheaper - but - it’s also allowing us to predict enzyme function and activity in a cell free environment. In other words, AI is expanding our potential for discovery and accelerating development of each inspired prediction." Watch the entire panel here: hubs.la/Q03vC1xR0 #enzymes #exozymes #alphafold #proteinstructure #LLM #AI #ML #artificialintelligence #WBM25 $EXOZ @OpenAI

RT @eXoZymes: Dr. Tyler Korman (@tylerkorman), co-founder and VP of Research at @eXoZymes, on BioClick - supported by a NIH grant: “With o…

From @ChemEngMag: “In our bio-transformations, getting rid of the cells avoids complexity and concerns about cell toxicity that are not usually present in traditional chemical catalysis. We are bringing on more of a traditional chemical mindset to an inherently biological transformation. Our reactions are inherently homogeneous, and we can do very complex transformations in one pot,” says Paul Opgenorth (@popgenorth), co-founder and vice president of development at @eXoZymes Full article here: hubs.la/Q03frc_t0 #exozymes #enzymes $EXOZ

Thank you @LouBasenese for the kind words - you totally get what we are doing and the potential of it!