@Hemepathguy

@KukMariya Myelolipomas are clonal. I published this a million years ago.

~65M adrenal mass, bx

@PathologyKate I would wonder about measles.

All of my viral stains are negative. It’s only in a focal spot of an otherwise benign lymph node.

@SibaElHussein So I'll reply, because Siba knows this is a hobby of mine. If MAL is positive, then PMLBCL. If all three P63, CD23, CD30, then yes PMLBCL. If only 2/3, then c/w. If only 1/3, then suggestive of...

Primary Mediastinal Large B-Cell Lymphoma: The large cells are “strongly” positive for CD20, PAX5 and CD30,with a subset showing positivity for CD23 #LJMFridayUnknowns #endcancer #lymsm #HemepathMDA

@GersonPaull_MD @kis_lorand The deposition of significant amounts of immunoglobulin almost always means a plasma cell neoplasm. As such, I would recommend evaluation of SPEP and staging appropriate for myeloma

@hemepathguy @kis_lorand Could it be evidence of a systemic disease that requires therapy? What comment would you make in regards to further work up, if any?

A benign cervical polyp with crystals 🤣👇👇👇 #gynpath #PathTwitter

@dr_AmnaQ @UMichPath @UMichRISE @UTHoustonPath @TheJPCNCR @BroojAbro Not a guess. That is intravascular large B cell lymphoma

Kidney with interesting findings. The stain is CD20. Any guesses? @UMichPath @UMichRISE @UTHoustonPath @TheJPCNCR @BroojAbro

We're Getting the Band Back Together!!! I'm thrilled to welcome everyone back for the 1st ISIMM webinar of the academic year. Please join Wednesday, September 17 at 11 am ET for @slusagar's lecture "IHC Correlates in Bladder Pathology." Register here: us02web.zoom.us/webinar/regist…

@MahaSakr19 I'd argue in bone marrow they are functionally the same thing.

@hemepathguy If in B.M Biopsy how can we differentiate intravascular from intrasinusoidal?

#hemepath Interesting case...kidney biopsy

@Jas_Mc886 Done - you may want to look at my old posts. Lots of hemepath images. Probably enough to make a book!

@hemepathguy Thank you! I always look forward to learning from your posts. I’d really like to learn from your experiences. Please follow me back I enjoy connecting with like-minded people here. @hemepathguy

#hemepath some examples of hemophagocytosis - case of HLH

@Jas_Mc886 No. It is quite rare. However, I have become more vigilant in looking for it in lymphomas, and raise the concern for HLH if I see "significant" hemophagocytosis.

@hemepathguy Amazing visuals! Is HLH something you see often? @hemepathguy

@sza_jhcyto @AmerSwid Crank up the light. if there are colors other than black it is tattoo pigment.

"Let your imagination run wild" - spotted in a benign mediastinal lymph node on EBUS FNA by my fellow on service @AmerSwid

#hemepath Langerhans cell histiocytosis

#hemepath. Bone marrow - Mycobacteria avium-intracellulare. H&E, PAS, AFB

#hemepath Sarcoid granuloma in bone marrow

#hemepath. Bone marrow. Ring granulomas in Q fever. I've also seen ring granulomas in primary exposures to COVID19

BM core, ALK and CD30

#hemepath PB and marrow smears. ALK+ALCL, leukemic!!

ALK stain and cyclin D1 stain! Rare T cell lymphomas can express cyclin D1

#hemepath ALK positive ALCL - CD30 stain

CD20 stain! Intravascular large B cell lymphoma