Hector Peinado

El creador Eddie Graf quiso mostrar lo que vive él cuando escucha música. Algo que se llama sinestesia y que permite "ver" la música. Es tremendamente bello.

We developed a single-molecule, multi-modal spatial genomics approach to visualize the structure and function of >100,000 individual extrachromosomal DNA (ecDNA) molecules in their native contexts. Preprint link at the end of the thread. (1/11)

We’ve trained a multimodal AI model to turn routine pathology slides into spatial proteomics, with the potential to reduce time and cost while expanding access to cancer care.

Really proud to share our Science manuscript. Did you know that microglia regulates fertility? Super cool work at @CNIOStopCancer. urldefense.com/v3/__https://w…$

Our view of new (& old but re-formulated) determinants of myeloid biology in tumors is out at @JExpMed. Amazing work from @nogales_pons @mariolamuna & #teresaaceña. And fantastic editing process with @Gaia_JExpMed (thanks!). Hope you like it, as much as we do #cancerimmunitylab

🔥 Chem(bio) friends, this one is big!! IRB Barcelona is opening a Group Leader position in Chemical Biology! 💜 If your research plan and vision are at the interface of synthetic chemistry, chemical biology, and biomedicine, please check the call! 👉recruitment.irbbarcelona.org/jobs/7334978-g…

Online Now: Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer dlvr.it/TRL2HP

🚨 New paper from our lab just published in Nature🚨nature.com/articles/s4158… Discover how 🌱 tumour formation is shaped by tissue context from the very beginning. ✨Fantastic team led by @GSkrupskelyte, Eduardo Rojo, Harikrishnan Ajith

DEADLINE EXTENDED to March 10 FEBS conference on Tumour Microenvironment 🌍Location: Fodele, Crete, Greece lnkd.in/d5YCFCRK FEBS Constituent Societies please help to circulate @SEBBM_es @ogmbt_ylsa @HSBMB_official @SIB_biochimica @Kemisamfundet @BiochemSoc @Turk_Biyokimya

@JudithAgudo1 @Aiims1742 @nyscf @parkerici @Nature Congrats Judith!! Abrazo

Metastasis kills most cancer patients and grows from invisible seeds. How do these seeds escape from attack by immune cells? These seeds harness stress hormones!🤯 ⁦thanks to ⁦@nyscf⁩ ⁦@parkerici⁩ for their support. Today at ⁦@Nature⁩ nature.com/articles/s4158…

I think there is a need for a complete re-think for organoid modeling. As long as the architecture of organoids that you produce is not directly compared to a 3D map of the organ (say, fallopian tube) or disease to be modeled, it will be approximate Here: science.org/doi/full/10.11…

La resolución microscópica 🔬acaba de dar un salto gigante! 🧬✨ Se ha presentado Seq-Scope-eXpanded, una tecnología que lleva la ómica espacial más allá de los límites ópticos convencionales. 🔬🚀 🤯 Tradicionalmente, ver dónde se activan los #genes en un tejido dependía de la resolución de los microscopios. Con esta nueva técnica, los científicos pueden mapear la expresión genética a una escala subcelular sin precedentes, ¡permitiendo ver detalles que antes eran invisibles! 🔍💎 ​Este avance es clave para entender enfermedades como el cáncer 🎗️ o problemas del desarrollo, ya que permite ver exactamente qué ocurre dentro de cada célula y cómo se comunican con sus vecinas. ​¡El futuro de la medicina personalizada y la biología celular ya está aquí! 🧬🌍 ​#Biotech #Genomics #SpatialOmics #ScienceNews #Innovation #CellBiology #SeqScope #NatureCommunications #Genética #investigacion #Ciencia ​🔗 👇 doi.org/10.1038/s41467…

Metformin inhibits nuclear egress of chromatin fragments in senescence and aging | Nature Aging nature.com/articles/s4358…

Detection of metastatic burden is a task for CODA, which maps organs in 3D and at single-cell resolution. More here: biorxiv.org/content/10.648…

FINALLY IN PRESS! Cancer cells don’t just survive mechanical stress, they adapt! 3D confinement leaves a nuclear imprint in leukemia cells, reshaping lamin B1, chromatin and gene expression. #mechanobiology #mechanomemory goo.su/wPladjG @CellPressNews @CellRepPhysSci

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A major work from our lab is out in Science! @ScienceMag, another key step towards a true demonstration of RNA self-replication. science.org/doi/10.1126/sc… (1/6)

Circulating tumor DNA as a biomarker in early phase clinical trials dlvr.it/TQxjNB

AI is cool and all... but a new paper in @ScienceMagazine kind of figured out the origin of life? The paper reports the discovery of a simple 45-nucleotide RNA molecule that can perfectly copy itself.

Congrats to @jmunozpe! and his team @biobizkaia for this important study in the field of EVs @ISEV_Journals @IsevOrg Thanks for this collaboration Javi! @CNB_CSIC @CNIOStopCancer. nature.com/articles/s4155…