Judith Steen

Molecular features of human pathological tau distinguish tauopathy-associated dementias: Cell cell.com/cell/fulltext/…

Huge congratulations to first authors Mukesh Kumar, Christoph Schlaffner, Shaojun Tang & Maaike Beuvink for their exceptional work!

🧠 NEW in @CellCellPress: Game-changer for biomarker development & targeted therapies. doi.org/10.1016/j.cell… #Neuroscience #AlzheimersDisease #Tauopathy #Proteomics #PrecisionMedicine #Biomarkers #Neurodegeneration #CTE #FTD #MassSpec #DrugDiscovery #BrainResearch #CellPaper

@CellCellPress: A Game-changer for biomarker development & targeted therapies. doi.org/10.1016/j.cell… #Neuroscience #AlzheimersDisease #Tauopathy #Proteomics #PrecisionMedicine #Biomarkers #Neurodegeneration #CTE #FTD #MassSpec #DrugDiscovery #BrainResearch #CellPaper

Check out our @Nature review with Tiannan Guo @guomics and Judith Steen @ionicwoman on recent paradigm shifts in MS-based proteomics - where the field stands and where its headed. #Proteomics #AI nature.com/articles/s4158…

You ever meet someone who you know will help change the world just by existing...then you get to know them and see how much they're actively doing to make a #betterworld. Allow me to introduce you to my friend and inspiration for all of our upcoming #MAPT projects, Linde Lee🤩 Kismet brought us together to watch Tim Miller's plenary presentation on tau-targeting therapies for @alzassociation #AAIC24 👉Add her @CureMaptFtd to see how a daughter's love and three sister's passion for finding a cure will be the catalyst the world needs for solving the mysteries of #tau accumulation in the brain. Grateful to @RCFNeuro and @virginiahughes for amplifying her voice.

Breaking News from Capitol Hill: The senate unanimously passed the bipartisan NAPA Reauthorization Act and the Alzheimer’s Accountability and Investment Act! 🎆 Thank you, advocates, for your hard work that has brought us to this moment. Next up, the bills head to the House floor for a vote. #NAPAAct #AlzInvestmentAct

A senior delegation from the Association of American Universities (AAU) visited IITB on Friday, 23rd Feb 2024 & interacted with Institute functionaries. Seen in the pic are Prof. Barbara Snyder, President AAU & Prof. Subhasis Chaudhuri, Director IIT Bombay.

@GarciaLabMS @BrodSquadUT @ASofiaHCosta @1jvaneyk @AnjaKarlstaedt @LabLaskin @PatrickLab_MS @BaljitKUbhi @drcandice_u @Gundrylab @bomba_ewa @MassSpecMommy @Caroline_Bartma @PaesLeme_lab @IsabelRUribe @StacyMalaker Thank you! @GarciaLabMS

Looks like this deadline got pushed out…that is great for folks who wanted to submit but weren’t going to make the previous deadline. I might be in that group 👀.

Kathrin Wenger Ph.D. Candidate

rdcu.be/dxzCJ Do you want to FLEX your Tau? To quantify the extent of modification and the absolute amount of Tau in your samples. 1) Read the Nature Protocol 2) Do the FLEXITau SteenTeam @BCH Kathrin Wenger, Arthur Viode, and Mukesh Kumar #Alzheimers #proteomics

We hope to better understand and block this form of tau. Findings appear in the journal Brain. #massspectrometry #proteomics #tau #Alzheimers #Neurobiology #BCH #Harvard #HMS

Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments academic.oup.com/brain/article-…

People with Alzheimer’s disease have tangles of misfolded tau protein in their brains. Using proteomics and other tools, we characterized an apparent precursor form of tau in the brains of people with Alzheimer’s that possibly initiates misfolding/ neurodegeneration.

Congratulations to Dr. Mukesh Kumar, Dr. Arthur Viode, Dr. Christoph Schlaffner, and Dr. Pieter Beerepoot from the Steen team! This results from an awesome collaboration with members of the Hyman Lab @MGH and the Steen lab @BCH.

@KislingerThomas @biorxivpreprint @PMResearch_UHN @TheBoutrosLab @UCLA Congrats to the team!

Happy to report our latest collaborative work with the Boutros Lab utilizing proteomics of prostate cancer urines is now available in @biorxivpreprint @PMResearch_UHN @TheBoutrosLab @UCLA

simply incredible

@FMKirbyNeuro @bch_rc @harvardbrainsci @harvardmed

Integrative systems biology characterizes immune-mediated neurodevelop... sciencedirect.com/science/articl… Dr. Fujimura, Dr. Guise, and Dr. Nakayama, I am in total awe of your beautiful work and tenacity!