
James Wise
652 posts

James Wise
@Jameswise
Partner @Balderton. Investing in AI, health and energy. Chair of UK Sovereign AI. Author of Start-Up Century. Mostly Generative.



🚨Sovereign AI Substack. 🚨 We've joined Substack. We’ll use it to share longer-form thinking on British AI, sovereignty, and the opportunities this technology presents for the UK. In the months ahead, we’ll be publishing perspectives from across the ecosystem - from founders, our growing portfolio of British startups, and leaders in industry. We're pleased to kick off with a guest post from our Secretary of State, @leicesterliz MP, reflecting on why the next 24 months will be critical for Britain's AI future, and what it will take to build true AI sovereignty. Subscribe and join the conversation.










On Tuesday, we held the official Sovereign AI North West launch in Manchester.🐝🇬🇧 It was brilliant to have 100+ local founders, investors, academics, researchers, and ecosystem leaders in the room. If Britain is going to build the next generation of globally significant AI companies, it needs this kind of collaboration across the UK’s entire ecosystem. Our Chair, @Jameswise, set out why this moment matters so much. AI is this generation's defining technology, and the UK starts from a position of real strength: world-class research, some early successes and increasing sovereign capabilities. However, now is the time to turn those strengths into globally significant companies that benefit each corner of the UK. James also spoke about why his home town of Manchester and the North West are such important parts of that story. While the City has an extraordinary history of technological firsts, its real advantage lies in the ambition and entrepreneurial mindset that continues to drive innovation across the region today. Rather than dwell on the past (we've all been to Quarry Bank Mill enough times now! ), Manchester's foundations at the frontier of chemistry, advanced materials and automated manufacturing make it the perfect launch pad for a new generation of future industries. This is why our UK tour has been so important for us. Great founders are building startups in every corner of the country, and each region has its own strengths. If we're serious about backing Britain's AI future, we need to be listening to our regional ecosystems, building long-term partnerships, and meeting founders face-to-face, wherever they are.

East Kent Hospitals NHS trust is the first in the country to use a potentially life-saving artificial intelligence tool that can help clinicians identify infections at an early stage. More here: bbc.in/3R3FPVn

Very sorry to have to have to do this, but I wanted to flag that @WeAreBrightBlue is owed £18,900 from the investment firm C5 Capital, who are now about 2.5 months late in paying two separate invoices for services we have delivered for them. We delivered one of these services in partnership with @thefabians. They wrote to me that these invoices would be paid in their payment run at the end of May. They then wrote that they would pay Bright Blue in their payment run at the end of June. This has not happened. They have provided no explanation for this. These payments are essential for the cash flow of our business and legally due to us. This is C5 Capital: c5capital.com

A German startup has just raised €411m to build the world’s FIRST nuclear fusion plant. It comes at a time when Europe’s energy security is being scrutinised more than ever. Germany in particular has been criticised for closing down all of its nuclear power plants, but this could see the country become a global energy powerhouse. Today @proximafusion has raised €411m at a €2.5bn valuation. This makes it one of the best funded fusion companies in the world! The company recently signed an agreement to build Europe’s FIRST Nuclear Fusion plant. If this works Proxima could truly become a trillion dollar company.

Quantum Systems has raised $1.2 billion in a funding round, more than doubling the German drone startup’s valuation to about $8 billion post-money, in the latest example of investors’ enthusiasm for defense-related bets. bloomberg.com/news/articles/…





