Jan Roediger

Two years, no sleep, but we did it! Real-life month-long adaptive deep brain stimulation in Parkinson's disease improves motor symptoms and quality of life compared to optimized standard stimulation.@scernera1 @LaurenHHammer1 @littleneuro PhilipStarr&team medrxiv.org/content/10.110…

Belated Season's greetings! Importantly, with novel sensing-enabled IPGs we can have true out-of-hospital insights into participants' electrophysiology. …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

Tiefe Hirnstimulation lindert Symptome bei #Parkinson – doch die Einstellung ist aufwendig. Ein Forschungsteam der #CharitéBerlin hat eine Software entwickelt, die dies künftig erleichtern könnte. #TiefeHirnstimulation @LancetDigitalH @AA_Kuhn charite.de/service/presse…

"Implementing automation in deep brain stimulation: has the time come?" is the editorial by @MarcoBonizzato and myself commenting on the interesting data-driven programming approach published in @LancetDigitalH by @jan_roediger, @andreashorn_ et al using @leaddbs.

Excited that our new study evaluating the effects of automated DBS programming based on electrode location using @leaddbs is now online @LancetDigitalH 🎉🎊💥 thelancet.com/journals/landi… many thanks to an amazing team of contributors!

This is the most inspiring and true article about academic success I read in a long time. Everybody should read this. By my former colleague @tukker_john elifesciences.org/articles/83251

Read an “@eLife digest” about our intraoperative multimodal mapping tool, Lead-OR, spearheaded by @simonoxen w/@c_neudorfer, @jan_roediger, @lukamneuro, @neumann_wj, @Chris_Guettler, @vajkoczy & @AA_Kuhn here: elifesciences.org/digests/72929/… Full paper: elifesciences.org/articles/72929

Over the past years we’ve been trying to use fMRI to streamline #dbs programming. This is crucial for #dystonia, where the effects are not immediate. Thank you @dmrf for your support. @ANA_journals @C_R_A_N_I_A @KBI_UHN onlinelibrary.wiley.com/doi/epdf/10.10…

Excited that @simonoxen’s Lead-OR toolbox paper has been published w/ @eLife today. Much has happened till the preprint so here’s a renewed tweetorial about Lead-OR: elifesciences.org/articles/72929

Wow, @ChariteBerlin, what’s happening? *Registering* a doctoral thesis takes 4-5 months? After successful disputation yesterday, we were told the candidate will need to wait until the end of November (!) What should candidates do in the meantime before applying for a postdoc?

Excited to share our latest study on beta band activity as a biomarker in chronically implanted DBS patients - out in npj Parkinson's disease nature.com/articles/s4153… realized in a great collaborative effort @Retune_CRC @rlofredi @AA_Kuhn @bahnebahners and many more!

@petryschmelzer @DembekTill @j_achtzehn @AA_Kuhn @andreashorn_ Thanks a lot Jan Niklas! You can find the stimulation data and corresponding UPDRS scores in the supplementary material. Happy to hear your thoughts on it and let me know if you need additional info :)

Excited to share our new preprint evaluating the effects of automated image-guided DBS in a clinical trial 👇 many thanks to this amazing crew @DembekTill, @j_achtzehn, @AA_Kuhn, @andreashorn_ and others not on twitter! medrxiv.org/content/10.110… (1/4)

This suggests that data-driven algorithms capable of suggesting DBS parameters according to individual patient anatomy and symptom profile could dramatically decrease programming burden for both patients and medical personnel. Curious to hear your comments and thoughts on this :)

Stimulation effects were compared to patients’ standard of care treatment in a double-blind cross-over design. Motor symptoms responded well to both stimulation conditions and non-inferiority of image-based stimulation was established. (3/4)

It was fun to co-write an outlook paper about ways to transform deep brain stimulation to a form of personalized medicine using connectomics with Nanditha Rajamani & @b_hollunder for our upcoming Connectomic DBS book. Full text of the chapter here: researchgate.net/publication/34…