Joshua Shapiro

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Joshua Shapiro

Joshua Shapiro

@jashapiro

not 'Eureka!' but 'That's funny...' https://t.co/CDaptBBfvG https://t.co/km0pxmOYlR

Wynnewood, PA Katılım Ocak 2008
1.2K Takip Edilen1.2K Takipçiler
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Joshua Shapiro
Joshua Shapiro@jashapiro·
"Its ultimate purpose is to secure justice and fair treatment to all citizens alike and to put an end forever to unjust and unfair discrimination against and ridicule of any sect or body of citizens."
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Vince Buffalo
Vince Buffalo@vsbuffalo·
Traveling to San Diego this weekend and I have two important questions for locals: where is the best burrito and where are the best tacos?
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Joshua Shapiro
Joshua Shapiro@jashapiro·
@lpachter I went looking for the code for mx assign, but could not track it down from the linked repositories in the paper. It looks very compelling!
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Lior Pachter
Lior Pachter@lpachter·
In order to assign cells to cell types we needed to develop an efficient and robust method. We developed a tool, mx assign, that assigns cells based on Spearman correlation for robustness. It performs very well and should be useful generally. 14/
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Lior Pachter
Lior Pachter@lpachter·
Our Commons Cell Atlas is built from 10x data, which is a 3' single-cell RNA-seq technology. So how did we manage to get isoform specificity? Well, many isoforms differ in their 3' UTR, and this was the case for p44b in OAS1. 10/
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Josh Miller
Josh Miller@joshm·
Hey @ArcInternet members – we need your advice: You are all *loving* our Arc Max (AI) features – seeing much higher opt-in & engagement rates than we expected. Which is awesome! But AI is expensive. How would you prefer we offer Max to you after the experimental period ends?
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Junwei Shi
Junwei Shi@junwei_s·
Our department is recruiting new faculty! I can't emphasize enough how supportive both the department and the scientific community are. Feel free to DM me if you have any questions.
Univ. of Pennsylvania Department of Cancer Biology@Penn_CBIO

🚨Our 2024 departmental faculty search is live! @PennMedicine Cancer Biology is recruiting for tenure-track Assistant Professors positions. Applicants with expertise in any area of cancer biology are encouraged to apply. 👇 apply.interfolio.com/130274

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Joshua Shapiro
Joshua Shapiro@jashapiro·
@fragmites Getting back into whitewater kayaking. And getting my wife to try it out.
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Dr. RA Cartwright
Dr. RA Cartwright@fragmites·
Science Twitter: Tell me something that has brought you joy recently. For me: Going to see movies again with my family.
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Andy Clark
Andy Clark@AndyClarkCornel·
Mariana Wolfner and I seek an enthusiastic postdoc to work on an NIH-funded project to dissect the molecular basis for male-female interactions during and after mating. Join the exciting Drosophila research community at Cornell. Email ac347@cornell.edu.
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Joshua Shapiro
Joshua Shapiro@jashapiro·
@arjunrajlab I assume a chunk of this is because manufacturing/production with consistent quality is expensive and difficult.
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Arjun Raj
Arjun Raj@arjunrajlab·
I generally agree. It is interesting to contrast with experimental work, where we typically are happy to trade opacity for convenience and there is less of an idealistic stance against proprietary commercial options.
𝕐@nomad421

Your periodic reminder that CellRanger (currently v7.1.0), while seemingly well-engineered software & documented with solid release notes, is still closed-source. It’s methods are fundamentally opaque. Good open methods exist, and should be the basis of our science instead!

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Laura Been, PhD
Laura Been, PhD@LauraBeen1·
Won't you be my neighbor? Bryn Mawr Biology is hiring a tenure-track neurobiologist! Come join a thriving Bi-College Neuroscience Community - exceptional students, great location (Philly!), beautiful campus, amazing colleagues! brynmawr.edu/inside/academi…
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Clement Chow
Clement Chow@ClementYChow·
What do we think of this combo?
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Joshua Shapiro
Joshua Shapiro@jashapiro·
@3rdreviewer Batch correction with highly multidimensional data is hard. (Impossible?)
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Matthew Hahn
Matthew Hahn@3rdreviewer·
Very cool work here
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