Jeff
11.6K posts

Jeff
@jepoymd_
🇵🇭 Isko l MD l Internist/Gastroenterologist l Mix of GI/Med Twitter and Philippine politics
Republic of the Philippines Katılım Eylül 2020
682 Takip Edilen1.4K Takipçiler
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⚠️ Proton Pump Inhibitor (PPI) Contraindications & Important Interactions with Anticancer Drugs
PPIs (pantoprazole, omeprazole, rabeprazole, esomeprazole) are extremely common in oncology patients, yet many oral targeted therapies require acidic gastric pH for optimal absorption.
This practical infographic highlights:
• High-risk interactions (Dasatinib, Erlotinib, Pazopanib, Acalabrutinib & more)
• BTK inhibitors, Capecitabine, CDK4/6 inhibitors
• Clinical impact & real-world consequences
• Safer alternatives & management strategies
• Key clinical pearls for daily practice
Critical for every medical oncologist!
Save | Share | Tag a colleague who needs this 👇
Made with ❤️ by Dr Rupam Manna
Cancer Concepts Explained
Follow for more → @DrRupamOncology
#Oncology #DrugInteractions #TKI #PPI #MedEd #MedTwitter #CancerCare #CancerConceptsExplained

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☺️ Honored to share that our work published in @UEGJournal ranked among the top 10% most-viewed papers published in 2024. @DeMadaria
Many thanks to all collaborators and readers for their interest and support. Delighted to share the article 👇
onlinelibrary.wiley.com/doi/full/10.10…
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Key take home messages from the peptic ulcer bleeding guidelines - presented today at #ESGEDays2026




Keith Siau@drkeithsiau
Management of peptic ulcer bleeding - updated ESGE guidelines unveiled at #ESGEDays2026 🩸🆕 📸: esge.com/assets/downloa…
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Jeff retweetledi
Jeff retweetledi
Jeff retweetledi

🚨 ASCITES IS NOT JUST “ABDOMINAL SWELLING” 🚨
Ascites = abnormal accumulation of fluid inside the peritoneal cavity, most commonly due to portal hypertension from liver cirrhosis. 🩺
⚠️ Important clinical points every healthcare worker should know:
🔹 New-onset ascites → ALWAYS do diagnostic paracentesis
🔹 SAAG ≥1.1 g/dL → suggests portal hypertension
🔹 PMN ≥250 cells/mm³ → think Spontaneous Bacterial Peritonitis (SBP)
🔹 Salt restriction + spironolactone = first-line management
🔹 Tense ascites → large-volume paracentesis + albumin
🔹 Refractory ascites may require TIPS or liver transplant evaluation
🧠 Common causes:
🍺 Cirrhosis
❤️ Heart failure
🦠 Tuberculosis
🎗️ Malignancy
🩸 Nephrotic syndrome
🔥 Pancreatitis
📌 Watch for complications:
⚠️ SBP
⚠️ Hepatorenal syndrome
⚠️ Hepatic hydrothorax
⚠️ Umbilical hernia
💡 Clinical pearl:
Not every ascites patient has cirrhosis — SAAG and ascitic fluid analysis are the keys to diagnosis.
Early diagnosis + guideline-based treatment can significantly improve survival. ❤️
#Ascites #Hepatology #MedTwitter #FOAMed #InternalMedicine #MedicalEducation #Cirrhosis #LiverDisease #EmergencyMedicine #CriticalCare #MedEd #Doctors #MedicalStudents #ClinicalPearls #SBP #Gastroenterology #Medicine #USMLE #PLAB #NEETPG #healthcarenotwarfare

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Jeff retweetledi

Jeff retweetledi

This updated Delphi consensus helps move MASLD/MASH care toward a more pragmatic and scalable fibrosis-centered model based on non-invasive testing, longitudinal monitoring, and real-world implementation. authors.elsevier.com/c/1n5ag5UiFSsN…

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Management of peptic ulcer bleeding - updated ESGE guidelines unveiled at #ESGEDays2026 🩸🆕
📸: esge.com/assets/downloa…

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Jeff retweetledi

📊 JAMA Clinical Guidelines Synopsis: #HelicobacterPylori infection is a leading cause of chronic #gastritis, #peptic #ulcers, and #gastric #cancer.
The American College of Gastroenterology guideline for adults in North America recommends bismuth quadruple therapy for 14 days as first-line treatment in treatment-naive patients, due to superior eradication rates compared with proton pump inhibitor (PPI) triple therapy.
ja.ma/4tq1d4x

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Akala ko DURIAN ang best product ng Davao.
POLITICIANS pala.
Jizas.
ALTStarMagic 💫@AltStarMagic
“Kaya niyo ho bang tingnan lahat itong legal remedies na sinasabi niyo po, exhaust all these legal remedies nang hindi po nagtatago na naman at diyan naman sa Senado?” KARMINA CONSTANTINO, THE FINAL BOSS!!!! HAHAHAHAHAHA PIKON NA PIKON NA SI PEBBLES TANGINAAA 😭😭😭
Filipino
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