James Dooley

BREAKING 🚨🚨🚨 Nicola Sturgeon urged to apologise after leaked WhatsApp messages describing Matt Hancock as “Weaker than a nuns piss,” Liz Truss as “About as much use as a marzipan dildo,” and referring to Suella Braverman as “Shitler.”

@PascalBielefeld @FitzFitzsimons @UvA_Amsterdam @sebastianmunck @BioImagingCore What next? We'd love to move into a #clinicaltrial. All the pieces are in place (thanks @ERC_Research PoC!) and the tech can be directly translated. Each year 50 million #traumaticbraininjury patients need treatment, and families need hope. 10/12

@PascalBielefeld @FitzFitzsimons @UvA_Amsterdam @sebastianmunck @BioImagingCore The great thing about this approach is that #Tregs are smart anti-inflammatory agents, able to deal with many different types of stress. We could hit with models of #stroke or #multiplesclerosis and saw the same protective effect! 8/12

The system increases #brain #Tregs 10-fold, creating an anti-inflammatory environment. With @PascalBielefeld @FitzFitzsimons @UvA_Amsterdam we tested in #traumaticbraininjury, and the results were immediate - we were able to prevent most neurological damage! 7/12

We teamed up with Matthew Holt @CBD_VIB @i3S_UPorto to design a system to feed extra #IL2 into the brain. The gene delivery system harnesses #genetherapy technology and #astrocyte biology, to bring brain IL2 levels up to the same level as the blood. 6/12

We had a great post-doc, @EmanuelaPasciu1, drive a project showing #Tcells in mouse and human brain, with key functions. Among these T cells were a small population of anti-inflammatory #Tregs, again in mouse and human. 3/12 cell.com/cell/fulltext/…

The work started more than 10 years ago, after my brother Russell died following a #traumaticbraininjury. The more I read into it, the more treatable #neuroinflammation seems. Obviously there is a #brain delivery problem, but stopping #inflammation is basic #immunology! 2/12

Excited to share our new paper out at @NatImmunol today! We discovered the limiting factor for #brain #Tregs is #IL2, and developed a new #genetherapy to treat #traumaticbraininjury and other #neuroinflammatory pathologies. 1/12 nature.com/articles/s4159…

@dkm14 Hope you are staying in Seattle!

Haven’t heard anything, per @dkm14

@Bwagz The fans adore you. We all are grateful for your time with us. The "Legion of Boom" and Beast Mode brought the Superbowl trophy to Seattle. Much respect!!

Crazy part about all this. I played there for 10 years & I didn’t even hear it from them that I wasn’t coming back.

@BorisJohnson @ZelenskyyUa I would like to think that Boris is genuine. I just don't buy it. He is saying what he says to look good. It is camouflage for action. All the actions taken so far are proposals with slow can complex implementation criteria. Looking beneath the surface all looks superficial.

I spoke to President @ZelenskyyUa this afternoon to set out how I will be working to advance Ukraine’s interests at meetings of NATO and the G7 this week. The UK will continue to step up military, economic and diplomatic support to help bring an end to this terrible conflict.

@justinbaragona What a crock. I do agree we would not be here today because Trump was doing what Putin and Xi Jinping wanted. Leaving NATO and destroying alliances with the EU and aligning with authoritarian governments. Democracy takes work too. Thank you Biden for restoring these priorities.

Jeanine Pirro says that Biden is a "wuss," "is responsible for the decline of the west" and that he's "destroying the west." After Geraldo asks how she knows "Putin wasn't playing Trump," she absolutely loses it. "Trump had everybody against the wall... [Putin] was a wuss!"

Help me win a Women in Science Puzzle from Nature bit.ly/3A447kM

We are currently seeking a Postdoctoral Research Scientist in Bioinformatics to work on an exciting international immunology project. Apply by Thursday 22nd April Full details: ow.ly/Xdhn50EiCxf Lab group: bit.ly/3cT2LzU #ScienceJobs #PostdocJobs #Immunology

Watch this. Trust me.

I gave an #AcademicJobs talk @UAlberta yesterday. My aim was to lift the veil on applying for academic research positions, negotiating a start-up and making the first steps in your new lab. Excessive honestly will likely land me in hot water, but... youtube.com/watch?v=dL-q5J…

It's finally here! Floreada.io now supports automatic compensation via Autospill (thanks to Dr. Roca and @LabListon). This was by far the most requested feature and we are excited for people to try it out. #flowcytometry #autospill

Interview in @nrc: over de grote gelijkenissen en kleine verschillen tussen de Belgische en Nederlandse aanpak van de Covid-19 crisis. nrc.nl/nieuws/2021/01…

If anyone would like to hear more about #IL2 #cytokine networks, #Treg feedback circuits and the curious linkage between #Bcells and #CD8Tregs, I just gave a talk on our pre-print story from @CarlyEWhyte and team: biorxiv.org/content/10.110… The talk is here: youtube.com/watch?v=J9z30N…

@jules_su As much as I feel there is plenty of dumb things this President has done. It is far more important to highlight the policy and court appointments that have been done since 2016 as these will have a real and lasting effect. Focusing on things like this is merely distracting us.

Since Trump’s almost out of office, I figured this would be a fun time to remind everyone of the weirdest & dumbest sh*t our failed dictator did in the last four years that we totally forgot about. Starting with a classic: STARING DIRECTLY INTO THE SUN DURING A SOLAR ECLIPSE