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Joe Win
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Joe Win retweetledi
New Preprint: AMBER and GOLD: Polycistronic Genes for Betaxanthin Production in Plants (2026)
tsl.ac.uk/publications/1…
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Joe Win retweetledi
Inspired by the story, I created a petunia with 5 differently colored petals using new genes I made, AMBER & GOLD that I just published here: doi.org/10.64898/2026.…
Similar to RUBY, these polycistronic genes encode yellow, fluorescent betaxanthins 💛🧡
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Joe Win retweetledi
Why I’m genetically engineering a rainbow flower…
And how a Russian fairy tale inspired the idea 🧵
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Joe Win retweetledi
These are just the first parts and flowers of OpenFlower, a nonprofit aimed at creating designer flowers for art & education as a community 🧬✨
Stay tuned for exciting announcements!
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Joe Win retweetledi
With these genes, one can encode blends of pigments reaching a spectrum of colors.. Just look at this overlap of RUBY & GOLD .
DM or email me for the DNA parts, which have been whole plasmid sequenced thanks to @plasmidsaurus & @markwbudde !
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Joe Win retweetledi
Ever wondered what it's like to work in research support at TSL?
To find out, we asked Dr @Adeline_Harant, Senior Research Assistant in the @kamounlab, who told us about her career and her passions in and outside the lab.
Read the full interview here: buff.ly/e6gGB7j
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Joe Win retweetledi
Fantastic hosting the @GoogleDeepMind team at TSL with @KamounLab 🌱 From AI in plant health to building scientific capacity, our missions clearly resonate!
Tools like AlphaFold can accelerate scientific breakthroughs in our field -holding real promise for global food security 🌍
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Joe Win retweetledi
We sought to make proteins both potent and FAST. We used #proteindesign to design precise control over protein interaction lifetimes, enabling us to construct rapid-response circuits, biosensors, and switchable cytokines. Now published @Nature! Links to paper and tutorial below.
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Joe Win retweetledi
Introducing the 1,000 Flower Collection 🧬🌹
I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes.
Here’s how I’m making it happen… and how you can join me on this journey 🧵(1/7)
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Joe Win retweetledi
To promote the collection, I’ve launched a designer clothing line where synthetic biology meets aesthetics.
I will give out 100 free limited edition shirts to the first who retweet and order with their handle in the name! Available here → nickdesnoyer.com 🧵(6/7)
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Joe Win retweetledi
InterProScan 6 (beta) is here 🎉
A Nextflow-powered, containerised overhaul for scalable, reproducible protein annotation—decoupled software/data, automated data handling, and smoother runs across HPC and cloud.
Feedback welcome!
github.com/ebi-pf-team/in…
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Joe Win retweetledi
Population genomics reveals distinct lineage of the Asian soybean rust fungus Phakopsora pachyrhizi in the United States 🇺🇸unrelated to Brazilian 🇧🇷populations: bsppjournals.onlinelibrary.wiley.com/doi/full/10.11…
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Joe Win retweetledi
Another month, another insane protein design paper from the Baker Lab.
This time: Designing binders for intrinsically disordered regions, a common & important component of proteins we care about, with the help of a diffusion model
In @Nature last week
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Joe Win retweetledi
Thank you @GetGenome for sponsoring this fantastic meeting and fostering connections among global South researchers. In Argentina’s dire funding landscape, community and collaboration are key.
María Eugenia Segretin@EugeSegretin
Queremos agradecer a @GetGenome por ser sponsor de nuestra primera edición 2025 del #IMPP-AR. Compartiendo el espíritu de construir en comunidad 🫶🏼
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Joe Win retweetledi
A root-specific NLR network mediates immune signaling of resistance genes against plant parasitic nematodes (Daniel Lüdke , Toshiyuki Sakai , Jiorgos Kourelis , et al) doi.org/10.1093/plcell… #PlantSci @ASPB
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Joe Win retweetledi
It has been a while… but an updated, faster & more accurate version of OrthoFinder is now out!
Scales to thousands of species on conventional compute resources with higher accuracy than ever before and the same data rich fully phylogenetic outputs
👉biorxiv.org/content/10.110…
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Joe Win retweetledi
Effector Innovation in Genome-Reduced Phytoplasmas and Other Host-Dependent Mollicutes | bioRxiv biorxiv.org/content/10.110…
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Joe Win retweetledi
🎉 Exciting news during #2025ISMPMI
Our AlphaFold 3 sensor vs helper NLR paper is now published in @NewPhyt!
Big thanks to the reviewers for their constructive feedback 🙏
📖 Check out the peer-reviewed version here 👇
🔗 nph.onlinelibrary.wiley.com/doi/10.1111/np…
x.com/YuSugiharaY/st…
Yu Sugihara@YuSugiharaY
Please check our latest paper on using @GoogleDeepMind AlphaFold 3 to study NLR immune receptors. Here we use AI-guided structural modelling to distinguish between sensor and helper NLRs! 👇🧵 (1/10) #EvoMPMI #NLRbiology #PlantPath #PlantSci doi.org/10.1101/2024.1…
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Joe Win retweetledi
🚨New @biorxivpreprint alert!
We are thrilled to share our latest findings—building on our earlier work on suppressors of helper NLRs of NRC family—a Phytophthora infestans L-shaped effector captures resistosome assembly intermediates of tomato NRC3! biorxiv.org/content/10.110…
1/10
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Joe Win retweetledi
Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies | Science Advances science.org/doi/10.1126/sc…
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