Jonathan Grubb
2.7K posts
Jonathan Grubb
@jonathangrubb
CEO @ Triangle Health. Formerly: Bird, RVIP Lounge, OpenTable, Lookout, Get Satisfaction, Rubyred Labs, Yahoo, Vodafone, Valleyschwag, etc.
South Pasadena Katılım Ocak 2007
483 Takip Edilen1.2K Takipçiler
@Techmeme @ashleycapoot This jury would be so much more fun than the minivan lemon law case I got stuck with
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Jury selection begins in Musk v. Altman trial at a federal courthouse in California, with Sam Altman and Greg Brockman in attendance (@ashleycapoot / CNBC)
(Visit Techmeme dot com for the link and full context!)
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@pmarca The future: intimate, personal, human, face-to-face, handshake deals, doing business with friends, membership clubs, vouching for people, singer-songwriters, stand up comedy, gardening, farmers markets, baristas who remember your order.
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@bryce I always tell younger friends: if I had it to do again, I’d start earlier and have more. It’s easier with high income, but nothing will focus you like a pile of kids.
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Get married too young, have too many kids, give them a front row seat to what it takes to build a lit life so that when you’re in your 50s they can keep you young and you can thoroughly enjoy helping them build lit lives of their own.
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Jonathan Grubb retweetledi
We thought this would happen. AI is the best thing to happen in healthcare but it should be AI + a Doctor not AI instead of a doctor.
statnews.com/2026/04/24/doc…
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@binarybits @alexolegimas We're seeing a global instance of the "End of History" fallacy. Every technological advancement in history has led to more jobs, but THIS TIME IS DIFFERENT and the new technology will lead to fewer jobs instead.
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This essay by @alexolegimas is the best thing I've ever read on why AGI won't lead to mass unemployment. A compelling argument backed up by substantial empirical data.
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Jonathan Grubb retweetledi
I’ve become pretty convinced cancer vaccines are going to be a big part of how we manage cancer.
There are a few types — off-the-shelf, dendritic cell, and fully personalized neoantigen vaccines that target your tumor’s exact mutations.
I went the personalized route after a grade 2 astrocytoma diagnosis. My vaccine was built from my tumor, and I fly to Germany every few months for shots. You can actually track your immune response to the peptides over time, which is pretty wild.
Still early, but seeing more and more data suggesting these can help delay recurrence. Feels like a shift coming. nbcnews.com/health/cancer/…
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@ninjudd Like sheet music. It's always the same song, but each instance is something new.
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What if we stopped distributing software as code, and started distributing it as spec?
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Jonathan Grubb retweetledi
We are building this at Triangle Health, Patrick. I met you years ago when you came to Singapore and I was at Shopify. Let me tell you a quick story: I found out I had brain tumor through resting @prenuvo and after getting it removed I went deep on my genetics and my tumors genetics. That lead me to a treatment path where I am taking a personal cancer vaccine and an IDH inhibitor. During all this investigation I found out I have a rare genetic condition called Li fraumeni syndrome. Rare genetic disease that leads to cancer. I got luck catching my tumor early. That all said- we launched @trianglehealthx to be able to integrate ai with your health and right new we are beta testing a wgs addition to it which I have found crazy powerful.
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@MattLoszak @dropalltables Nuclear waste hysteria is hilarious because:
1) you can just put it in the basement at the power plant and use it later.
2) our current plan is to store, fossil fuel waste in the air.
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if you took every gram of "nuclear waste" the US has ever produced and extracted the remaining energy with a breeder, you'd power the entire country for >100 years.
Nuclear waste is not waste.
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@paulg I learned this deeply when we started A/B testing design changes (at OpenTable/Booking.com). 70% were negative, 25% were nominal, maybe 5% were positive and made up for the rest. Lots of a little steps back, a few big steps forward, can’t guess which is which.
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Something I taught 14 yo: Most progress is a mix of steps forward and steps back, just with with more of the former. But you can get a run of steps back. So to judge progress accurately you need to use a big enough window, or it could look like you're failing.
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@lennysan @WisprFlow I told my sister about it this morning and she called to say how good it is. Bonus irony of Apple voicemail transcription getting half her words wrong.
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Get 1 year free of @WisprFlow with your Lenny’s Newsletter subscription
Tanay Kothari@tankots
18 months ago, i was sitting alone in my office launching @WisprFlow on Product Hunt. Today, Wispr is taking over the entire @ProductHunt homepage for 3 days - and powering it with voice! producthunt.com
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@kevin2kelly The best gift of travel is understanding what it feels like to be another person, in another culture. Time gets you there.
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For the best travel experiences you need either a lot of money, or a lot of time. Of the two modes, it is far better to have more time than money. Although it tries, money cannot buy what time delivers. You have enough time to attend the rare festival, to learn some new words, to understand what the real prices are, to wait out the weather, or to get to that place that takes a week in a jeep. Time is the one resource you can give yourself, so take advantage of this if you are young without money. #KKtraveltips
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@thulme "The Mythical Man Month" was published in 1975 and we're still getting our heads around this one. Don't change a perfect team, replicate it.
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I think they're saying if you have a news site that tweets links, and you don't tweet them manually, you now have to pay X hundreds of dollars per month?
Developers@XDevelopers
API Posting will increase to $0.015 per post from $0.01. API Posting URL will be $0.20 except for summoned replies. This will remain at $0.01. Following, Likes, and Quote-Posts via API Writes will be removed from all self-serve tiers. More details: devcommunity.x.com/t/x-api-pricin…
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Jonathan Grubb retweetledi
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Most people will just think you have a super helpful friend.
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PSA: you can refer to any AI as "my buddy."
"My buddy coded it."
"I'll have my buddy drive us there."
"This is way too long, did your buddy write it?"
Try it, it'll stick.
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