Jon Wong

Screen all kids between 2 and 10 for high cholesterol, pediatric society recommends ctvnews.ca/health/article…

Check out the new CPS position statement entitled "Dyslipidemia in children: Diagnosis, evaluation, and management". Congrats to @PeterDWong @makhoury! Stay tuned for our webapp to help providers action these recommendations. cps.ca/en/documents/p…

Published today, Screening, Diagnosis, and Management of Pediatric Hypertriglyceridemia A Scientific Statement From the American Heart Association. Triglycerides enter the circulation by ingestion [BE1.1](exogenous pathway) and endogenous production. Triglycerides within chylomicrons and VLDL are hydrolyzed by endothelium-bound LPL, which releases free fatty acids (FFAs) and leaves remnant particles. LPL function is enhanced by apo CII, apo AV, intracellular chaperone lipase maturation factor 1, and GPIHBP1 (glycosylphosphatidylinositol anchored HDL-binding protein 1). LPL function is downregulated by apo CIII and ANGPTL3 and ANGPTL4 (angiopoietin-like proteins 3 and 4).21 📷 Triglyceride metabolism

Check out our newly published AHA Scientific Statement on Pediatric Hypertriglyceridemia. A great experience chairing this statement with an amazing team. @AHAScience @uoftmedicine

Where did that S come from anyway? We’ll probably never know. But we can easily know our cholesterol numbers. It just takes a simple blood test. Check in with your doctor about your numbers.

Early diagnosis and treatment of FH reduces the risk of #cvCAD by 80%. Improve detection and diagnosis of FH and get to know the new treatment options for patients with ACC's online course ➡️ bit.ly/3vNLMqW #RareDiseaseDay #FamilialHypercholesterolemia #ACCEd

Important tips for building heart-healthy habits in children!🫀 #HeartMonth

3️⃣ tips to optimize your child's heart health from a Paediatric Cardiologist!🫀 Did you know heart disease develops over time, starting from childhood? That's why it's important to start teaching heart-healthy habits like these early. More➡️ bit.ly/3F6GoY5 #HeartMonth

Resistance Exercise Training in Individuals With and Without Cardiovascular Disease: 2023 Update #AHAJournals ahajournals.org/doi/10.1161/CI…

👉The Long-Term Efficacy and Safety of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia (HoFH) ☝️ PERSPECTIVES COMPETENCY IN MEDICAL KNOWLEDGE: Patients with HoFH are difficult to treat, with standard-of-care LLTs providing limited LDL-C-lowering efficacy, especially in patients with absent or severely impaired LDLR activity. In this open-label extension of the phase 3 ELIPSE HoFH study, evinacumab, an ANGPTL3 inhibitor, demonstrated sustained LDL-C reduction in patients with HoFH regardless of LDLR function and irrespective of background LLTs. TRANSLATIONAL OUTLOOK: Although randomized clinical trials are the gold standard for determining the efficacy and safety of a treatment, the strict application of inclusion and exclusion criteria and monitoring of participants means that trial populations and observed treatment effects are often not representative of patient populations in a real-world clinical setting. Thus, real-world evidence studies are needed to determine whether the observed LDL-C-lowering effect with evinacumab in the clinical trial setting is replicated in real-world patients with HoFH and whether long-term therapy with evinacumab in HoFH patients will reduce cardiovascular events and prolong their lives. 🔓Open Access jacc.org/doi/epdf/10.10…

Q: What are the optimal daily step counts needed to significantly reduce CV risk? A: The optimal volume of 8,763 steps/day resulted in 60% risk reduction in all-cause mortality & 7,126 steps/day for 51% risk reduction of incident CVD bit.ly/3ZMJqqY #cvPrev

30% of FH women risk Atherosclerotic Cardiovascular Disease (ASCVD) by age 60 ⏳. It strikes 20yrs earlier for them 😮🩺. Post-ASCVD, women are 10% less diagnosed than men. Time for a change 💪❤️: bit.ly/44s75xw #PeopleLikeUs #FindFH #HoFH #HeFH #FHAware2023

The NLA and the @foundationofnla support the @AmerAcadPeds recommendation that all children should receive dyslipidemia screening between 9-11 and again between 17-21 years old. ow.ly/Wirs50PIpgj

Nutrition myths are widespread and easy to fall for. It’s time we dismantled some longstanding misconceptions about nutrition and heart health to set you up for a lifetime of healthy eating. Learn the truth behind artificial sweeteners, nuts and more: bit.ly/3OhnrUR.

Family Meals and Cardiometabolic Risk Factors in Young Children ⁦@CarissaBakerSm1⁩ & colleagues link.springer.com/article/10.100…

Do interventions to decrease sedentary behaviors help prevent and manage childhood obesity? Check out our review on the topic below for the answer. 📺🛋️📱. @SKHeartCentre @BCH_HeartCenter doi.org/10.1007/s11883…

Red meat consumption, cardiovascular diseases, and diabetes: a systematic review and meta-analysis bit.ly/42GBdEu @escardio #EHJ #ESCYoung @rladeiraslopes @ehj_ed

Looking at percent daily value (% DV) on a food label is a simple way of finding out if one serving of food has a little or a lot of a nutrient. Read more about % DV and other items on a food label: ow.ly/mVUH50OKAHT #Nutrition #NutritionLabel #FoodLabel

"Develop a framework for lifestyle modifications for the management of pediatric dyslipidemia..." #HCPs join Dr. Jonathan Wong, clinical research fellow @SickKidsNews, for "Paediatric Dyslipidemia Guidelines Update". 📅May 25 | 12-1pm REGISTER⤵️ sickkids.echoontario.ca/om-zoom-regist… #MedEd

Excited to attend the @nationallipid meeting this week in Atlanta! Starting off the week with the Masters in Lipidology course and ending with a poster sharing our Lipid clinic's experience with our rapid dietary assessment tool called the HEAT 🥬🍌🫒🐟