Jon Ipsaro

@yuangao_yg @Xueyan_He @megeblad @Xiaoli_Sky_Wu @leemorj @pkoo562 @KMBaileylab @ChrisVakoc The pleasure was mine! Congrats again, Yuan 🥳

Super excited to share our study that uncovers ETV6 as a key growth dependency in Ewing sarcoma! Huge thanks to our amazing co-authors @Xueyan_He @megeblad @Xiaoli_Sky_Wu @jonipsaro @leemorj @pkoo562 @KMBaileylab, and my super PI @ChrisVakoc doi.org/10.1038/s41556…

@CrollTristan Also agree with DeepEMhancer. Seen it many times. Spikes are way too sharp to be anisotropy problems IMHO.

Can any #cryoEM folk tell me what on earth is going on in the low contours of this map (EMD-32679)?

When you get the wrong image from the title of this featured journal article during your routine lit searches… 🧵

Sky Wu (吴小丽) @xlw1207 was such a joy to work with on this project. I can't say enough good things about her. Smart, well-rounded, hard working, and fun. A Nature paper and a newly-minted Ph.D! Way to go! nature.com/articles/s4158…

@DhananjayHuilg1 @jessemaurica @WilliamGalbavy @borshuen @ShreyasMSurya Woohoo! Awesome! Hope you can celebrate a bit while it is under review! 🥳

Thrilled to announce the submission of this study from my postdoctoral work! It wouldn't have been possible without the perseverance and talent of my collaborators who helped this study see the light of the day. @jessemaurica @WilliamGalbavy @borshuen @ShreyasMSurya

still some fine tuning to do, but JWST is now fully deployed! So impressive and exciting!🔭🌟#JWST #NASA

It's finally here! So excited for the launch of the JWST! T-minus 10 minutes 🚀 nasa.gov/nasalive #NASA #JWST

@oncogenie Yes. It can’t manage to remain stable at a reasonable pH and temperature long enough to make experiments easy. 🤣

@jonipsaro Thanks Jon! I saw that paper, so cool. Is there anything RNA can’t do?!

First glycoRNAs and now: RNAylation!

@cryoET @CSHL @leemorj Hahaha! Good memory. #givesmethesketches

@jptosar Very clever 🤣

Par Toutatis!

@RiccardoGuidi87 2. In P19 (mouse) and OSS (fly germline), the eCLIP protocol has a mild RNase treatment in addition to bioruptor shearing, so that may have fragmented things enough to help with sequencing. Again, if anything, we expect our already huge enrichment to be an underestimate

@jonipsaro Amazing work! How did you get tRNA seq to work?! It's not easy with the tertiary structure.

Finally! cell.com/cell-reports/f…

@RiccardoGuidi87 Hey, sir! Good to hear from you! So there were a couple of contexts. 1. Recombinant xpsn in Sf9 with our protein - Used a commercial sRNA seq kit. We were shocked at how abundant the tRNA reads were and, because of the tRNA structure, it is probably an underestimate 😱

@fmuerdte You are in the shout-outs, @fmuerdte! 🤗

@KeerthiKrishna3 😳

What?!!!

Had some fantastic interactions presenting at the University of Utah’s RNA interest group! Thanks to @BassLabUtah’s Helen for the smooth planning! Good times!

@CancerHacker @WhiteheadInst Congratulations! Super envious! Go rock it! 😎

#BlackinCancerWeek #BlackinCancer Inspiring to see black scientists from all levels. And a great week to announce that my lab will launch in Feb 2021 @WhiteheadInst. We will develop new tools to understand and induce anti-tumor immunity in pancreatic cancer.