Jonathan Rittmo

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Jonathan Rittmo

Jonathan Rittmo

@jorittmo

Failed poet. Neuroimaging, statistics, Alzheimer's and aging. PhD Student in DeMON lab #rstats.

Katılım Mart 2020
193 Takip Edilen92 Takipçiler
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Lijun AN | 安丽军
Lijun AN | 安丽军@anlijuncn·
[1/7] Our work is now out in @NatureMedicine nature.com/articles/s4159… We developed a state-of-the-art AI-proteomics model for diagnosing multiple neurodegenerative diseases from blood plasma. See previous thread for a summary – but some updates in the published version described below. ProtAIDe-Dx now outperformed both classic machine learning models and even foundation models like TabPFN!
Lijun AN | 安丽军 tweet mediaLijun AN | 安丽军 tweet media
Lijun AN | 安丽军@anlijuncn

Can AI reveal the risk and co-pathology of multiple neurodegenerative diseases from just a single blood sample? We explored the AI-based diagnostic power on a massive sample (N=17,170) and high-rank plasma proteomics data. medrxiv.org/content/10.110… #MedSky #neuroskyence #neurosky #Alzheimer #compneuro #AI #datascience #bioinformatics #neurology

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Pavan Chaggar
Pavan Chaggar@ChaggarPavan·
‼️ New preprint ‼️ How do amyloid-β (Aβ) and tau drive Alzheimer’s disease over time? We introduce a parsimonious, mechanism-based dynamical ATN (dATN) model to simulate longitudinal imaging biomarkers. A short thread 👇 Preprint: biorxiv.org/content/10.648…
BioFINDER@biofinder_study

New BioFINDER preprint! We formalise the Aβ–tau–neurodegeneration (ATN) framework into a mechanism-based model of AD, enabling us to simulate longitudinal imaging biomarkers and study how disease processes evolve and interact across the AD continuum. 🔗biorxiv.org/content/10.648…

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Harry H Behjat
Harry H Behjat@aitchbi·
does 🧠 connectivity drive spread of pathological proteins in Alzheimer’s disease? if this question intrigues you, please check out our new preprint: biorxiv.org/content/10.110… and/or read on.. 🧵⤵️
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Thomas Lin Pedersen
Thomas Lin Pedersen@thomasp85·
I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN. It's not every day we have a new major hashtag #ggplot2 release but it is a fitting 18 year birthday present for the package. Get an overview of the release here: tidyverse.org/blog/2025/09/g…
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BioFINDER
BioFINDER@biofinder_study·
🚨New paper alert! Our study led by @teanijarv investigated why some individuals with Alzheimer’s disease (AD) develop hemispheric asymmetry in tau pathology and what drives this phenomenon. Out now in Nature Communications! 🔗Full article: doi.org/10.1038/s41467… A thread🧵👇
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Jonathan Rittmo
Jonathan Rittmo@jorittmo·
As my first PhD proj I’m v happy to finally share our findings with the world! It’s been a ride, and I am immensely grateful to the tireless @_JakeVogel_ for putting up with me + our team for all support: DeMON lab (@xiaoyucaly @anlijuncn @LeawChauveau and all ppl not here) 10/
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Jonathan Rittmo
Jonathan Rittmo@jorittmo·
How does the brain reorganize in the context of age and AD? Are functional changes in age and AD similar? Are these changes dynamic across the age/AD spectrum? We unpack these questions in a sample of N=973 with AD biomarkers Preprint: tinyurl.com/ymv8s7h8 1/ ⬇️🧵
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BioFINDER
BioFINDER@biofinder_study·
‼️New preprint! We are happy to share our latest work led by @teanijarv investigating why tau pathology in Alzheimer’s disease (AD) often accumulates more in one hemisphere of the brain than the other. Check out🔗biorxiv.org/content/10.110… or dive into the details below👇
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Jake Vogel
Jake Vogel@_JakeVogel_·
‼️PhD Position now available in my lab‼️ Do you like: * Neurodegenerative disease? * Neuroimaging and/or multi-omics? * AI and data-driven life science? Want to work with @RikOssenkoppele Alexandra Young and Laura Wisse? Apply here: lu.varbi.com/what:job/jobID… Please rt/share 🙏
Jake Vogel@_JakeVogel_

Whelp. Maybe a good time to mention that I am about to open a new PhD position in Sweden that just happens to be exactly four years in length. Any aspiring PhD candidates in neurodegenerative imaging or multiomics who want to "take a break" from the US, please get in touch!

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QC
QC@QiaochuYuan·
very weird part of this GPT cyborg scenario is that GPT is proprietary and not open-source tho. that is itself also a very cyberpunk kind of scenario i feel like someone should have explored in scifi already
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QC
QC@QiaochuYuan·
plato had this exact reaction to writing. i don't say this to trivialize the reaction, actually i think the parallel is very deep, that we'll be seeing a change in human consciousness as big or bigger than the change brought about by the invention of writing
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GREG ISENBERG@gregisenberg

Just had a fascinating lunch with a 22-year-old Stanford grad. Smart kid. Perfect resume. Something felt off though. He kept pausing mid-sentence, searching for words. Not complex words - basic ones. Like his brain was buffering. Finally asked if he was okay. His response floored me. "Sometimes I forget words now. I'm so used to having ChatGPT complete my thoughts that when it's not there, my brain feels... slower." He'd been using AI for everything. Writing, thinking, communication. It had become his external brain. And now his internal one was getting weaker. Made me think about calculators. Remember how teachers said we needed to learn math because "you won't always have a calculator"? They were wrong about that. But maybe they were right about something deeper. We're running the first large-scale experiment on human cognition. What happens when an entire generation outsources their thinking? Don’t get me wrong, I’m beyond excited about what AI and AI agents will do for people in the same way that I was excited in 2009 when the App Store was launched. But thinking out loud you got to think this guy I met with isn't the onnnnnly one that's going to be completely dependent on AI.

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