Josh
1.8K posts

Josh
@jpattco
A sight for sore eyes is the devil’s demise.








Histamine/MCAS in the gut can cause anxiety, migraines, skin rashes, brain fog, etc. Recommended approach 1. Starve & disable the bacteria directly - Lactoferrin binds iron that gram-negatives like Klebsiella feast on, literally starving them. - Green tea / EGCG disables the specific bacterial enzyme (histidine decarboxylase) that turns histidine into histamine. - Saccharomyces boulardii lowers histamine-producing bacteria, increases DAO (the enzyme that breaks histamine down), and creates a more acidic environment that favors good bugs over Klebsiella. 2. Fix the terrain so it can’t come back - Restore stomach acid & digestion: Betaine HCl + digestive enzymes, DGL + aloe vera, digestive bitters. - Optimise bile: Taurine, glycine, phosphatidylcholine (and short-term ox bile if needed) strong bile is naturally antimicrobial and keeps gram-negatives in check. - Repair the gut lining & lower oxygen: Zinc L-carnosine, N-acetyl glucosamine, butyrate, PQQ + B1 (restores mitochondrial oxygen consumption so the small intestine stays low-oxygen and unfriendly to Klebsiella). - Thicken mucus & calm mast cells: Boswellia, PEA.

Being ideologically pro-fiber is tremendously incompetent nutritional advice. Fiber is utterly catastrophic for someone with a Crohn's-related intestinal obstruction and can put them in the emergency room. Clinical guidelines are restrict fiber to less than 5 grams per day. Fiber is NOT a good solution for constipation in IBS-C. This meta-analysis claimed in the abstract that there was "no evidence that fibre was effective in the relief of abdominal pain in irritable bowel syndrome" but the data shows that insoluble fiber made abdominal pain 22% worse and soluble fiber made abdominal pain 33% worse. The only good advice about fiber is to self-experiment with different types and amounts of fiber from different whole foods, focusing on the food itself, to see which gets you closest to 1-2 bowel movements per day of well formed poop that comes out easily without straining. Any other advice about fiber is catastrophically stupid and likely to hurt someone.



















