Javier F Torres-Roca

When I was a young piano student I had the privilege of being on stage with him, turning the pages for the pianist during a recital. He then invited me to go to dinner with him and we spent the night talking about art and music. One of the most amazing nights of my life…

Today, we remember the courage of those who landed on the beaches of Normandy 80 years ago to defend freedom and defeat tyranny. America deserves a president as good and steadfast as our nation, a president of character, driven by a noble purpose, one who honors the sacrifices of our troops. Not a man consumed by spite, revenge, and self-pity. GreatTask.com

As an aside this is the first cohort done with FFPE, opening the door to many more retrospective cohorts and also making translation easier… 8/8

We’re pretty excited about this finding - for patients who will receive radiation, GARD has a stronger statistical effect than HPV status did when it first came out - we think calculating GARD should be considered in staging! 7/n

Now what if we if we found two optimal dose cut points and randomized patients to a trial of de-escalation? (In the spirit of HN005). Well - we find that if you stratify your randomization by genomic ‘group’ you can achieve equipoise with dose de-escalation! 6/n

We then asked how GARD (which is predictive of radiation effect) compared to other prognostic models, and, even alone, it outperformed them. Then - if we ADD the genomic information to our know clinical variables we recover a far superior model! 5/n

Asking first the most ‘standard question’ for a biomarker - which if you recall, GARD has an extra dimension compared to - cutting at the median GARD, do we see differences? Yes. 4/n

It was a pretty heterogenous cohort of HPV+ OPSCC patients so we separated all those that got radiation. Then focused on the one who got what we considered standard dosing (orange dots). As usual - we observe a large spread in GARD relative to dose. 3/n

After we saw a beautiful analysis of the Big Data 2 Decide project that included a dataset with affy metrix, outcomes, and details on XRT, we got really excited and contacted our now co-authors to collaborate. Genomics played a role - would GARD? 2/n pubmed.ncbi.nlm.nih.gov/34738049/

I have also been off Twitter now X for quite sometime but both Jake and I are really excited about this new GARD analysis #GARD #RSI

@jmmrad @WashURadOnc @ASTRO_org Indeed what a sad day for the radiation oncology family. His textbook is a classic… My condolences to his family

It is with profound sadness that I share the news of today's passing of Dr. Carlos A Perez, former Chair of Radiation Oncology at Washington University and the Mallinckrodt Institute of Radiology. @WashURadOnc @ASTRO_org beckerexhibits.wustl.edu/mig/bios/perez…

Super excited to share these news along with @CancerConnector

Pianist Glenn Gould, seen here the morning after performing Ravel's Piano Concerto for the Left Hand with the United States Marine Band.

@IUradonc @AmyLeMDMPH @CAustinCurtis @MWeismanMD @MayElbannaMDPhD @drchenx @AsamoahFA_Md Thanks for the invite @IUradonc. It was a lot of fun!! Keep warm

Thank you to our virtual 🖥️ visiting professor yesterday @jtorresroca ! The department really enjoyed hearing about your research leading to integrating genomics into clinical practice and the residents enjoyed spending additional time with you as well 🧬

Historic photo of two brilliant musicians when they were young and embarking on their luminous careers - maestro Claudio Abbado and pianist Martha Argerich. The partnership resulted in a 2005 Grammy award for Beethoven Piano Concerto No. 2 and No. 3. #piano #conductor #music

Genomic-Adjusted Radiation Dose Explained [2022] @CancerConnector @CleClinicMD @jtorresroca @emily_C_ho #ASTRO22 #OncoTwitter medicusnetworks.net/3FB7Lbf

@lauremarignol @Roxy_BioMath @ESTRO_RT We agree! Both @CancerConnector and I would love to participate

Taking in the natural beauty before the science starts! Excited for an amazing return to in person. Can't wait to see you @RRS_RadRes #RRS2022 #RadRes2022