Marianne

The planet can spell your name – literally. 🔤🌍 This Earth Day, see your name written in landscapes captured by Landsat: go.nasa.gov/4ak4Cdu

Chancellor Rachel Reeves proudly describes the food served at breakfast clubs: 🥣 Cereal 🍞 Toast 🧃 Juice On a point of order, all of those things are terrible for you

@RogerSeheult Yes studies on Autism and Hashimoto’s also

If it is true that oxidative stress is the common denominator in women giving birth to autistic children then you should see autistic children being born to mothers with more oxidative stress such as in diabetes: A 2025 meta-analysis published in The Lancet Diabetes & Endocrinology pooled data from over 56 million mother-child pairs and found that maternal diabetes (type 1, type 2, or gestational) during pregnancy is associated with a 25% higher risk of autism in the child. thelancet.com/journals/landi… Another 2025 systematic review and meta-analysis calculated that in utero exposure to maternal type 2 diabetes (T2D) and gestational diabetes mellitus (GDM) moderately increased the offspring's risk of developing autism (pooled OR: T2D = 1.48; GDM = 1.31) pubmed.ncbi.nlm.nih.gov/39809006/ The 2013 systematic review in PMC highlighted putative mechanisms: maternal hyperglycemia increases free-radical generation and impairs antioxidant defenses, leading to oxidative stress in the fetus. This oxidative stress is directly linked in multiple studies to neurodevelopmental disorders, including ASD. pmc.ncbi.nlm.nih.gov/articles/PMC41… Recent large pooled analyses also confirm a robust association between gestational diabetes and autism diagnosis (up to 56% higher risk compared to non-diabetic pregnancies), emphasizing a likely pathophysiological role for oxidative stress during gestation. nature.com/articles/d4158… Again, multiple hit theory means that for some that have more oxidative stress, those that take tylenol might cross the threshold. Might explain why population with less diabetes (Sweden) is negative - tylenol doesn't get them over the threshold - but in the US it does because of the prevalence of oxidative stress.

September sunlight isn’t just a mood boost it’s the final download of UV and IR codes before the long dark. UV isn’t optional. It tunes your aromatic amino acids into serotonin, dopamine, melatonin, the chemical architecture of your mood, sleep, and focus. Infrared isn’t a warm afterthought. It thickens the EZ water around your proteins and supercharges your mitochondria. Miss these weeks, and your winter runs on empty fields. Easter Egg Hunt for seekers: Which neurotransmitters shut down first when UV vanishes? How does infrared water structuring decide whether ATP even works? Why do mitochondria uncouple in cold immersion to make their own UV? Fosbury showed the sky still hides UV in winter twilight, at the horizon, not overhead. And cold immersion sparks endogenous NIR/UV from within. That’s your insurance policy against winter depression, fatigue, immune crashes. This isn’t “biohacking.” It’s biology. And the window is closing. But winter has more options than you think! Stay connected any way you can. Nature gives us options you just have to know where to look —DrGrimmMD

🚨🌎 “This is the Biggest Medical Advancement in Medical History - Made my a Desperate Man trying to save his Dying Wife” Holy Crap - Mark Malone has designed a way to restore Human Genes & Eradicate Cancer Cells all without invasive methods. This Man needs some serious protection - Big Pharma don’t want this getting out there.

We cannot understand the true nature of the Universe, unless we question deeply. I want to know what is real, even if the answer is total obliteration of my consciousness.

@DrJackKruse Bottom left is different; it’s worth 2 points. 5 and 10. Easy

@stella_chadwick I agree with you Stella. I always felt there’s got to be something - why do some kids get it and some don’t.

Not every child with #PANS is gifted. But in my clinic, a pattern keeps repeating. The most severe cases, the deepest crashes, the longest recoveries, are often children who were exceptional before onset. 🧠 Off the charts memory
🗣️ Early, complex language
🔍 Intuitive reasoning before school age 
Then: rage, OCD, shutdown, confusion This is not coincidence. Here’s my hypothesis. These brains are different from the start. High functioning. Highly tuned. But also more vulnerable. Immune activation → glutamate surge → NMDA and AMPA overstimulation
 In the short term, it sharpens performance
In the long term, it overwhelms regulation These are not average brains pushed below average
These are fast, efficient, high capacity systems thrown into inflammatory chaos We’ve mapped the patterns in clinic
We’ve seen the same genes show up
We suspect a divergent glutamate mechanism in many of these children A new study of 680 children with PANS just confirmed what parents have said for years
Over 80% were described as gifted - especially in memory, language, creativity, maths This is not overreaction
This is not just anxiety
This is a neuroimmune crisis targeting the very systems that once set them apart 📄study in comment 👇
 #PANS #PANDAS #Neuroimmune #Giftedness #GlutamateHypothesis

A UTI can make an elderly person delirious, paranoid, even psychotic - and no one questions it. It’s standard medicine. But a child develops OCD, rage, food refusal, hallucinations after strep or a virus - and suddenly it’s “just anxiety”? Really? We’ve known for decades that infections can mess with the brain. That inflammation can hijack behaviour. That immune cells talk to neurons. So why is it still taboo to say a reactivated virus, strep, Mycoplasma or chronic inflammation could cause neuropsychiatric symptoms? Why is psychiatry still acting like the immune system doesn’t exist? In our clinic, we see it all the time: ➡️Kids misdiagnosed with “mental illness” ➡️Underlying infections ignored ➡️Immune dysfunction missed ➡️Told “it’s all in their head” But here’s the thing:
It is in their head.
It’s just coming from their immune system. Until medicine wakes up, children will keep slipping through the cracks - mislabelled, misdiagnosed, and misunderstood. Link to blog in comments 👇 #Neuroinflammation #PANDAS #PANS #FunctionalMedicine

@stella_chadwick Thanks 🙏🏼 Just so difficult when you don’t know the root cause. Do you have thoughts on why some are affected by this pathway? Genetics maybe?

Quinolinic acid rises when inflammation pushes tryptophan away from serotonin production and into the kynurenine pathway. Common triggers are Chronic infections (like strep in PANDAS/PANS), gut issues, oxidative stress, and mitochondrial dysfunction. We see it a lot in clinic - addressing the root cause is key!

“Your child has OCD, anxiety, and aggression. It’s just who they are.” No. It’s who they’ve become because of unchecked infection-triggered neuroinflammation. We see it every day - kids misdiagnosed, medicated, and written off when they could heal. James was 9 when he lost himself to fear and rage. His parents were told it was psychiatric. But we found chronic strep, sky-high quinolinic acid, and an immune system in overdrive. We treated the root cause. He got his life back. How many more kids are out there, waiting for someone to look deeper? #PANS #PANDAS #Neuroinflammation #PansPandasHour

Everything we're being told, and have been told, about everything, is utter, utter bollocks. That is all.

🫠

@elonmusk Dark mode and red light mode (but then you can’t read any of the hashtags 🙄)

Dark mode is the way

What did Starmer know about Southport, and when did he know it? He wants these questions to fade away. That must NOT happen.

I have a genetic predisposition to hoarding. True story.

Nobody wins in a nuclear war

The balloon has gone up. Hug your children. #Russia #Ukraine #Biden #Starmer @MoatsTV

Time to lose some followers. Nothing personal, this just isn’t a semi-‘professional’ account anymore ✌🏻

🚨 IMMIGRATION CRISIS, UK AT BREAKING POINT The DELTA 'Marriot' HOTEL in WARWICK has closed down to the public, with immediate effect after taking a contract with the Home Office to house 360 ILLEGAL IMMIGRANTS Local residents who literally live within a few yards of the hotel have had absolutely no communication from Warwick District Council about this change of use which appears to have happened literally overnight The Delta hotel on the A429 Stratford Road, Warwick, has 180 bedrooms all with free WiFi, and 50inch televisions, the hotel has a large gym and also has 14 on site meeting rooms