Karthik Subramaniam Kalyankumar

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Karthik Subramaniam Kalyankumar

Karthik Subramaniam Kalyankumar

@karthukally

PhD @UniMuenster/Structural_Biologist/CryoEM/DigitalArtist

Nordrhein-Westfalen, Deutschla Katılım Kasım 2011
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Karthik Subramaniam Kalyankumar
I stayed up just to see Artemis II come back… and somehow it felt personal. Watching that moment, knowing they were out there and are finally home again, it hits differently. Sleep can wait. Moments like this don’t come often. ✨ #ArtemisII #nasa
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Ravi Sharma
Ravi Sharma@ravishar313·
I tested models from @AnthropicAI @OpenAI @Google @Zai_org @MiniMax_AI and @Kimi_Moonshot on whether they can create a publication-level view of a protein-ligand binding site and the results were surprising. TL;DR: Anthropic models did the best and Gemini models did the worst. Task was simple: "Load 5DEL and create a publication ready view of the ORO and FMN binding site" Here are the results: 1. Sonnet 4.6 from @AnthropicAI: - Fast - Used the tools pretty well - Created the best view with clear labelling and color choices - always felt in control of what it was going for - very impressed
Ravi Sharma tweet media
Ravi Sharma@ravishar313

I am Open-Sourcing PyMolAI! Meet PyMolAI, an AI agent that can talk to your protein structures. Built on top of PyMOL, PyMolAI lets you interact with your structures in plain language. Whether you're: - Analyzing protein structures - Aligning complexes - Creating publication-ready figures - Or running design workflows PyMolAI interprets your request, executes the necessary PyMOL commands, and manages the workflow for you. It integrates with @OpenBioAI APIs, giving you access to tools like Boltz, ProteinMPNN, and BoltzGen — directly from your PyMOL session. It has local chat history with session syncing, so you can pick up exactly where you left off.

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nature
nature@Nature·
“People are feeling hopeful, and that’s a good thing” Can GLP-1 drugs help cut cravings for cigarettes, alcohol, and opioids - as well as food? go.nature.com/4pMw1L9
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rcsb pdb 💉🧬💻🔬💊🌱🧠🦠
GLP-1 receptor agonists got their start in an unlikely place: the mouth of a lizard. A peptide discovered in Gila monster saliva, called exendin-4, was found to mimic the action of GLP-1 and was developed into the drug exenatide (Byetta) for type 2 diabetes treatment.
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242 souls on AI171 , from students flying out for the first time to parents, tourists, maybe even newlyweds. A flight so many of us have taken. Today’s crash hits harder when you’ve lived that goodbye. Heartbroken for all onboard. 💔 #AirIndia #AI171 #Ahmedabad
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Aditya Raj Kaul
Aditya Raj Kaul@AdityaRajKaul·
“If Pakistan escalates it, we have really the capacity to punish them harder” - India’s Top Diplomat Vikram Doraiswami
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Karthik Subramaniam Kalyankumar
@therjrajesh Does Image generation also work on it ? Had a bad time when one such All in One thingy didn't have the ability to do Image Gen using the latest GPT 4o
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Rajesh Kumar
Rajesh Kumar@therjrajesh·
I just canceled my ChatGPT subscription. Because I found an all-in-one AI tool that 10x better Here's how to use it↓
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CheMTraP
CheMTraP@CheMTraP_MS·
We thank Prof. Andreas H. Guse @UKEHamburg for sharing his great expertise about NAADP and calcium signaling with us @CheMTraP_MS @uni_muenster.
CheMTraP tweet mediaCheMTraP tweet media
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Karthik Subramaniam Kalyankumar
Attended a JournalClub led by @DvdGently on his Nature paper titled "Structure of the native myosin filament in relaxed cardiac sarcomere." Exciting insights on myosin, titin & MyBP-C organization, plus great discussion on data processing. #CryoEM #cryoET #tomography
Karthik Subramaniam Kalyankumar tweet mediaKarthik Subramaniam Kalyankumar tweet media
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Its an honor to be part of this journey and contribute to our research.🎉 A huge thanks to Prof.Christos Gatsogiannis @gatsogia ,Dr.Bjoern Udo Klink and the @Sfb1348 for their support !
Gatsogiannis Lab@GatsogiannisLab

"Ever wondered how α-latrotoxin, the black widow spider's 🕷️ neurotoxin, turns into a cation-selective channel? Check out our latest manuscript! rdcu.be/dWez3 @NatureComms #Neuroscience #Toxin #cryoEM @Sfb1348 @uni_muenster

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The Nobel Prize
The Nobel Prize@NobelPrize·
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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Simon Duerr
Simon Duerr@simonduerr·
There is a new tool on BioIcons to turn any protein (in PDB format) into a 2D vector illustration in SVG format. You can upload any PDB file or import from PDB, AlphaFoldDB or ESMFoldDB. Feedback welcome :) bioicons.com/pdb2vector/
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@sfb1348.bsky.social
@sfb1348.bsky.social@sfb1348·
Congratulations to our poster price winners Bapin Kumar Panda, Dennis Hoffmann and Karthik Subramaniam @Sfb1348 meeting @uni_muenster
@sfb1348.bsky.social tweet media@sfb1348.bsky.social tweet media
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Karthik Subramaniam Kalyankumar
A big thank you to @SFB1348 for organizing such a fantastic event and for this award. I am deeply grateful to Prof. Christos Gatsogiannis @gatsogia , and Dr. Bjoern Udo Klink, for their incredible support and guidance. #Research #Science #SFB1348 #membranes
Gatsogiannis Lab@GatsogiannisLab

Such an exciting meeting on "Molecular Mechanisms of Membrane organization" @Sfb1348 @uni_muenster crc1348.ycode.site Also congrats to Karthik for winning a poster prize! 🥳

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