Kristina Micheva

Lipofuscin granules are actually beautiful! Array tomography of human cortex.

@alon_douek I second @EM__Ian . Looks to me like they may be specifically within astrocytes, definitely not random and not lead. If you have serial sections I bet you could follow the same mysterious objects through the sections.

Any #TEM experts able to weigh in on something? We are seeing these small electron-dense things in brain. Not sure if it's real (samples are from a storage disease) or artifactual, but it looks worryingly like lead precipitate... #SciTwitter #ElectronMicroscopy

What a week at the #arraytomography workshop in Munich. Vivid exchange and great fun. Grateful for support from @czi, @SyNergy_Cluster and industry. Missed it? Stay tuned for Buenos Aires 2025: lnkd.in/dgSaXpTp @kdmicheva @JemimaBurden @MSoizaReilly

@EM__Ian Thank you! We missed you!

@kdmicheva @MaSchifferer @JemimaBurden @MSoizaReilly @czi @DZNE_en Happy Birthday!

Delicious & unique #arraytomography cake at the AT Workshop in Munich 2024! Thank you @MaSchifferer @JemimaBurden @MSoizaReilly @czi @DZNE_en

Great kick-off of our Array Tomography Workshop in Munich 2024🔬🎊 supported by @czi @DZNE_en with @MaSchifferer @kdmicheva @JemimaBurden and many other AT experts #arraytomography

@JemimaBurden @LMCB_UCL Congratulations! Exciting news!

Delighted to announce that from October 2024, I can call myself "Professor"!🥳 This wouldn't have been possible without inspiration, encouragement and support from colleagues @LMCB_UCL, #UCL and beyond (you know who you are!🤗) & family and friends cheering me on! 🙏 #grateful

@BWJones @RPB_org Congratulations!

@DaniBeckman Thank you for all your beautiful image and informative posts! You've created so many positive connections here, hopefully one day we bump into each other in real life! Take care of yourself 🌷🌻🪻

5 days of hands-on learning, discussions and talks + gorgeous electron microscopy and immunofluorescence ➡️ apply now!

Just look at this: axon is blue, astrocyte is in red, myelin loops (oligodendrocyte) are green. Axon initial segment remodeling in action! Congratulations to Miki Furusho and Mark Terasaki @aminiata for this important work!

Beautiful #volumeEM detective work: oligodendrocytes, astrocytes and neurons are definitely up to something at the first myelin segment! Journal of Comparative Neurology | Systems Neuroscience Journal | Wiley Online Library …rary-wiley-com.laneproxy.stanford.edu/doi/10.1002/cn…

@ricoy_labua @SuperOlish @neuro_mex Congratulations!🎉

@nanopharmNC I so want to go to this conference! 🧠&⛷️

10 women in STEM pick it up and keep it moving! @JoJoBuchanan1 @HaniehFalahati @ahmari_lab @AdemaRibic @ClaudiaLopez_EM @Meng2Fu @doctheagrif @MocaerK @Sci_Wanderlust @S_Nowotarski

In this #ImagingTheFuture Week we are launching our @cziscience funded community website on #ArrayTomography for AT enthusiasts and those who would like to know more! arraytomography.org #volumeEM @volumeEM1 @kdmicheva @JemimaBurden @aminiata @MSoizaReilly

@DaniBeckman Looking at plaques in the brain always brings this contradiction of how can something so nasty look so beautiful!

Happy #MicroscopyMonday! Going back to my roots with some amyloid in this 3D image 🤓🔬! It shows two different markers for amyloid pathology: 🔴Anti-Amyloid Fibrils OC;🟢Thioflaving S: a Dye for β sheet-rich deposits found in misfolding protein diseases. Surrounding this amyloid plaque are some very activated astrocytes (🔵Gfap). You can see some delineating a blood vessel nearby, passing in the middle of the amyloid plaque. @zeiss_micro

@MKirkcaldie @aniai_commune I kept this for my weekend read, and so glad I did - thank you for this engaging piece! It is a great reminder to look beyond the "cellular scale", across that gulf to the human/animal mind.

@MattRGR None of these 😄 It's postembedding immunofluorescence on ultrathin sections of the brain embedded in Lowicryl, then heavy metal staining and SEM (conjugate IF-SEM array tomography).

Color-coordinated EM. Chapter 2. Autumn synapses with #webknossos

This is gorgeous! What blows my mind however is that you managed to find the same tiny cilium, 10 years later, and take an even better image of it!