Kessler Group Oxford
298 posts
@kesslerlabox
Mass Spectrometrists at the Target Discovery Institute, University of Oxford
Want to profile your favourite protein's molecular environment? Here a detailed APEX2-based protocol applied to spatially resolve the NLRP3 inflammasome @Zhu_L_Oxford @AndreasDamiano2 @flassen_ @ProteomOX @CAMS_COI_Ox @CmdOxford sciencedirect.com/science/articl…
Congratulations to our DPhil student Pauline Lascaux, all our lab members, and collaborators worldwide @NTUsg @NTU_LKCMedicine @OxfordOncology @institutrb @VdangioE3lab @nunoraimundo on the role of nucleophagy in DNA repair. Please check: doi.org/10.1016/j.cell…
USP24 is an ISG15 cross-reactive deubiquitinasethat mediates IFN-I production by de-ISGylatingthe RNA helicase MOV10 biorxiv.org/cgi/content/sh… #biorxiv_biochem
Our latest manuscript on a new cell cycle dependent control of dna repair. Started from a high resolution crispr screen of #ubiquitin system after IR: check table S2! Also substrates of cyclin f through motif search! science.org/doi/10.1126/sc…
Excited to share this editorial on non-canonical ubiquitination [frontiersin.org/journals/molec……]. Huge thanks and congrats to my amazing co-editors and co-authors @Sapmaz_A, Jin Gan, and @darraghpobrien and all the contributors to this research topic! #Ubiquitin #Ubiquitomics
