Kevin Eisenfrats

With new provisional birth data released by the CDC today, we see the same trends continuing. Total births declining, but also shifting older at the same time. Average mother's age was close to 27 in 2007, 28 by 2013, 29 in 2018, and now almost 30.

@zach_yadegari If only it was real

I was in the room when Eric came up with the idea for Sperm Racing. I thought in no world would he pursue it. He did and it's crushing.

@garrytan that company @contraline was also in YC's fellowship way back in the day.

Trae Stephens Wants to Buy Wired. He’s Right. A 2011 article about male birth control became a Founders Fund investment. That’s what great journalism does. Wired forgot. garryslist.org/posts/trae-ste…

3/ The worst part is that Wired used to be filled with incredible pieces that framed my thinking around the future, like this one from April 2011 about new birth control methods for men that eventually led (nearly a decade later) to @foundersfund making an investment in a company commercializing the tech @contraline. wired.com/2011/04/ff-vas…

@m_franceschetti My wife: does 8 sleep want to come over and train our dog? 😂

Do you sleep with your pet? Here is what you need to know. Across 2,200+ nights, we learned that what mattered most for your sleep quality is where your pet sleeps. Pets sleeping near your head → 46 fewer minutes of sleep per night. Pets sleeping by your feet → no meaningful impact on sleep or recovery. Training your pet to sleep at the foot of the bed could unlock 5+ more hours of sleep weekly.

@theallinpod @friedberg @DrMakaryFDA Phenomenal interview @friedberg!

All-In Interview: FDA Commissioner Dr. Marty Makary @friedberg sits down with @DrMakaryFDA for a comprehensive convo on his overhaul of the FDA: -- Safely accelerating clinical trials -- US vs China in biotech -- Fixing the Food Pyramid -- Rethinking vaccines with common sense -- Cutting drug prices -- Power of AI in healthcare (0:00) Friedberg intros FDA Commissioner Marty Makary (3:21) Inside the 40+ major FDA reforms in 10 months (7:51) The China Race: Winning back biotech leadership (13:14) Accelerating drug approvals safely, how to cut down on clinical trial timelines (33:13) Reshaping the failed Food Pyramid (41:29) GLP-1s and America’s Obesity Epidemic (49:54) Rethinking vaccines from first principles (59:40) Lowering drug prices, the power of AI for healthcare (1:18:57) What causes autism?

@Geiger_Capital And yet you don’t show it’s #6 for women who voted for Trump. There’s a bigger question here as to why Gen Z women prioritize having children less than men, and politics isn’t the only reason.

This is insane… NBC polled Gen Z (18-29) on what they consider important to have a successful life. Having Children: 🔴 Men who voted Trump - #1 🔵 Women who voted Harris - #12 (last)

@jburnmurdoch For all the talk about the birth rate issue, I have yet to see any real solutions, any surveying of women or men on their challenges, or any programs that would make this easier for folks. We'll talk about it forever and do nothing.

@Suhail We’re working on male contraception 🤷🏻‍♂️

What is the most unhinged crazy startup someone is working on right now that is still less than 20 people?

The great filter might just be contraception.

proud early investor🫡

Come see Contraline pitch at the 2025 Innovation Nexus Conference. Register today! bit.ly/3FrvMU5 #AUAInnovationNexus #AUA25 #Urology

Great news! The FDA updated testosterone product labels today. The TRAVERSE trial found no increased CV risk, so the boxed warning is planned to be removed! However, a blood pressure warning has been added after ABPM studies. Use remains limited to men with medical conditions causing low T.

@melindagates Why not ever fund new male contraceptives? If you want to make a huge dent in preventing unintended pregnancies, the other half of the population needs more options and ownership. Plus, the new administration could view male contraception in a more bi-partisan way.

Contraceptives are a life-changing, life-saving tool that women around the world depend on to safeguard their health, their families, and their futures. But today the Trump Administration acted to reinstate dangerous global health funding restrictions that will limit access to contraceptives and other essential reproductive health services—which evidence shows will cost women and children their lives. I have heard from women firsthand about what happens when they lose the right to decide if and when to get pregnant, and it is why I am so steadfastly committed to putting more power in the hands of more women all over the world.

Dozens of labs around the world are striving to grow models of human embryos to study development, fertility and therapies. They are entering uncharted ethical territory. go.nature.com/3Zqr6FT

@AppleHelix Happy to chat. Contraline’s hydrogel tech allows for this

But adding a startup idea for a half-life extended mAb in slow release hydrogel that enables Q6M to yearly dosing

The other interesting oral presentation is Adocia’s hydrogel semaglutide formulation for potentially once monthly injection.

It’s #EqualResearchDay! 💥 Evvy created #EqualResearchDay on June 10 because women weren’t required in U.S. clinical research until June 10th, 1993 (Think Equal Pay Day but for the gender health gap!) Learn more and get involved: equalresearchday.com

This is the photo of the year.

This week on the Found podcast, @DominicMadori and @rebecca_szkutak talk with @kfrats from @contraline about getting the first long-lasting but reversible male contraceptive to market. Give it a listen! 🎧 techcrunch.com/2024/05/07/kev…