KPL ApS

🇫🇮🔬 We're at #FinnProt2026 in Espoo, Finland! Our CTO @HdezRollan is presenting a poster with the latest from our R&D pipeline 👀 Stop by to get an early look at what's next from KPL! #Proteomics #MassSpectrometry #TeamMassSpec

🚀 New #proteomics product: Trypsin/Lys-C Premium Mix With the right formulation, you can add Lys-C and Trypsin together instead of sequentially. 🧪 One tube ⏱️One incubation 📉 Best-in-class missed cleavage rates 🌱 100% recombinant kplbio.com/trypsinlysc/

Introducing Trypsin RMS - our third product is here. Recombinant. Methylated. Sequencing-grade. The robust Trypsin #proteomics labs need, without the batch variability of animal-derived alternatives. Learn more: kplbio.com/trypsin/ #TeamMassSpec

The following year, Kühne coined the term "enzyme" (from Greek "en zyme", in yeast). Fun fact: many sources say "trypsin" comes from Greek for "rubbing" because Kühne ground up the pancreas. That's a myth. It actually comes from "thrýpto", meaning "I break".

The answer is 1876. German physiologist Wilhelm Kühne discovered trypsin while working at the University of Heidelberg. He extracted it from pancreatic juice and showed it could digest proteins outside a living organism.

Trypsin is the workhorse of bottom-up proteomics. But when was it first discovered? 🤔🤔🤔 (Answer in the comments)

New publication alert!📢 KPL collaborates w/ @JesperOlsenLab on the first systematic comparison of LysC enzymes for proteomics published in @JProteomeRes A. lyticus LysC: >90% cleavage efficiency, >97% specificity Read more: pubs.acs.org/doi/10.1021/ac… #TeamMassSpec #proteomics

Happy Holidays from KPL! 🎄 Our first full year: 2 product launches, lots of foundation building, and countless hours pushing #proteomics forward. Our commitment: high quality, high performance, competitive prices. No compromises. 2026 is looking exciting - stay tuned! ✨

Really curious to get peoples experience with using SCIEX instruments for bottom up proteomics 🤔🤔 Remember you can post anonymously so please share the price as well ! 😅

A user is requesting input to decide between SCIEX or Thermo for proteomic MS instrument. Time for people to shine and share their experience. old.reddit.com/r/proteomics/c… #Proteomics #Teammassspec

#proteomics choose your fighter! reddit.com/r/proteomics/s…

🚀 Our very own @ucdmrt & @HdezRollan will be at Nordic Conference in Mass Spectrometry & Proteomics 2025! 📅 Sept 1-3 | 📍Odense, Denmark 🔬Presenting the latest protease innovations! Posters on Sept 1 and 2! kplbio.com/kpl-aps-to-unv… #MSP2025 #Proteomics #TeamMassSpec

To bead or not to bead? We evaluate five plasma proteomics workflows, finding bead-based methods enhance detection but show high susceptibility to cellular contamination bias. Strategies to optimize biomarker discovery in plasma proteomics. doi.org/10.1101/2025.0…

🚨 Check out our new study on proteomic profiling in premetastatic colorectal cancer! Accross 412 tumors, we define molecular subtypes with distinct functional landscapes and revealed CAVIN1 as novel biomarkers for relapse risk. embopress.org/doi/full/10.10…

Announcing a new product launch at @asmsnews 2025! What is in ReSyn Biosciences new kraft box? Let's make it a little more interesting... First person to correctly guess and post in the comments gets one for free!?!

❄️ WINTER SALE ALERT! ❄️ Big savings on our products! Cozy deals that'll warm your heart and your wallet. 🔥 Shop now before these cool prices melt away! Find out more here: kplbio.com/product/lysc/ kplbio.com/product/arg-c/ #proteomics

Antibodies

I am excited to share our latest publication in Science Advances! We mapped the proteome of interstitial fluid across the leg in response to exercise, discovered immune cell derived peptide regulating muscle growth @morten_hostrup @Metabolcenter @PRI_UCPH science.org/doi/10.1126/sc…

🚨 Our #singlecell article is out! We describe the Chip-Tip label-free SCP workflow quantifying >5000 proteins in single HeLa cells. With high scalability, increased depth and throughput we can now envision large-scale LFQ-SCP biomedical studies! nature.com/articles/s4159…

1/11 - With @KMitosch and Clément Potel + colleagues in @savitski_lab @TypasLab @embl, I’m very happy to share our discovery of a hyper-promiscuous phage protein kinase (T7K) which broadly deactivates bacterial defenses! biorxiv.org/content/10.110…