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I'm happy to report the publication of our latest #proteomics paper has been published in @NatureComms . Thanks to the reviewers and editors who helped us improve the manuscript!
A small 🧵below
nature.com/articles/s4146…
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Tanveer Batth
4.4K posts
Tanveer Batth
@ucdmrt
Co-founder/CEO @KPL_ApS , Proteomics researcher in Copenhagen, Denmark @UCPH_health @NNFCPR . science, technology, culture, memes and vibes.
Copenhagen, Denmark Katılım Haziran 2008
1.3K Takip Edilen1.1K Takipçiler
@michaelsteidel1 I think this place is pretty dead, I think you might get a more immediate response on Bluesky or old.reddit.com/r/proteomics/
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#TeamMassSpec
Has anyone actually done a clean head-to-head comparison of TMT quant on AstralZoom-Orbi vs TOF?
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Tanveer Batth retweetledi
Sci-Hub is an evil website that pirated 85M+ research papers and made them freely available
And now they've added AI to their database to make Sci-Bot.
It answers your questions using latest, full-text articles.
But DO NOT use it. We should all try to make billion-dollar academic publishers richer.
I'm putting the link below so you know how to avoid it.
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Tanveer Batth retweetledi
@VincentRK I think at this point you probably can't detect it. I would recommend asking for mass spectrometry proteomic validation of the antibody results. That is more difficult to fabricate at the moment.
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As an Editor of a medical journal, this is concerning. We are already struggling.
Can some AI person tell me how we detect this especially if the image is resaved on another program and loses any AI tags from chat GPT?
Mikael Elias@elias_mikael
⚠️All of the below images were FABRICATED by ChatGPT Images 2.0, each with a single prompt❗️ ⚠️
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Tanveer Batth retweetledi
Does identifying thousands of plasma proteins mean more biology? Not always. Over half of 210 published datasets contain contamination markers reported as disease biomarkers.
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Tanveer Batth retweetledi
I’m looking for an automated way to read others’s scientific data without giving credit or acknowledgement, and also claim full credit for insights from it. And I want it to have a fitting name
OAI: say no more
OpenAI@OpenAI
Introducing GPT-Rosalind, our frontier reasoning model built to support research across biology, drug discovery, and translational medicine.
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Tanveer Batth retweetledi
reddit.com/r/proteomics/s…
Latest Bruker or Thermo #TeamMassSpec instrument for #proteomics? Please share your honest experience (anonymously if you want)! Sometimes it is more than just the specs (ie. price, robustness, maintenance, software)
#massspectrometry
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What peptide bros don't want you to know!
You can mix this little protein with other proteins and it'll produce countless amounts of peptides. All from the comfort of your home!!!
The possibilities are endless!!!
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Tanveer Batth retweetledi
Our latest paper with @atul_deshmukh1 is now out in @JPhysiol. We developed FibeRtypeR to infer muscle fiber type from transcriptome or proteome data. Would be great to receive feedback on it. @TeamDerave @ugent_fge
Paper: physoc.onlinelibrary.wiley.com/doi/10.1113/JP…
Tool: ccgg.ugent.be/shiny/fibertyp…
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Tanveer Batth retweetledi
Our latest #proteomics product to top off our Lys-C and Trypsin offerings.
A high quality optimal premix of Lys-C and Trypsin that enables reproducible proteomic analysis!
Make sure to follow @kpl_aps for more exciting news and updates! #TeamMassSpec
KPL ApS@KPL_ApS
🚀 New #proteomics product: Trypsin/Lys-C Premium Mix With the right formulation, you can add Lys-C and Trypsin together instead of sequentially. 🧪 One tube ⏱️One incubation 📉 Best-in-class missed cleavage rates 🌱 100% recombinant kplbio.com/trypsinlysc/
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Our recombinant, animal free, sustainable, artisanal 😁 Trypsin is here! High quality and high performance, drop in replacement for any existing #proteomic workflows
KPL ApS@KPL_ApS
Introducing Trypsin RMS - our third product is here. Recombinant. Methylated. Sequencing-grade. The robust Trypsin #proteomics labs need, without the batch variability of animal-derived alternatives. Learn more: kplbio.com/trypsin/ #TeamMassSpec
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Tanveer Batth retweetledi
It just seems implausible this is what we are made of, essentially, nanotechnology about a billion years beyond anything we can design or make ourselves.
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Tanveer Batth retweetledi
Does enzyme quality matter in #proteomics?
The study demonstrate that LysC combined with Trypsin reduces missed cleavages, ie. from 30% → 15% . And the source, quality, sequence of LysC enzymes can vary!
For challenging samples, adding LysC can make a big difference!
KPL ApS@KPL_ApS
New publication alert!📢 KPL collaborates w/ @JesperOlsenLab on the first systematic comparison of LysC enzymes for proteomics published in @JProteomeRes A. lyticus LysC: >90% cleavage efficiency, >97% specificity Read more: pubs.acs.org/doi/10.1021/ac… #TeamMassSpec #proteomics
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Tanveer Batth retweetledi
Tanveer Batth retweetledi
Thermo Fisher ($210B) is larger than Lockheed & Northrop combined
Fueled by M&A roll-ups, they make billions off instruments with crappy software & expensive service contracts
Why autonomous labs will need an Anduril for science instruments to suceed:
ml4sci.substack.com/p/antitrust-an…
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