Tim Krischuns

How does the influenza polymerase balance mRNA transcription and viral genome replication? Read our new pre-print: “The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome”! biorxiv.org/content/10.110… More detailed description below:

@florian_krammer @DrNeilStone Borna 😜

@DrNeilStone LOL, of all RNA viruses I can think of only influenza has any business in the nucleus. Most of the other ones - including hantaviruses - replicate in the cytoplasm. I recommend Fields Virology to Mary. It is helpful to understand the basics.

RIGHT ON CUE 😫

Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis #M1" target="_blank" rel="nofollow noopener">science.org/doi/10.1126/sc…

A research team from the Max Planck Institute for Multidisciplinary Sciences, Institut Pasteur, and EMBL has shown in a Nature paper how the influenza polymerase, a molecular thief, uses the host RNA to replicate. Check out the MPI press release: mpinat.mpg.de/5179649/pr_2604

Join us on Jan. 29 for JVI's first Seminar Series webinar of the year! Learn about zoonotic disease risks at traditional food markets. 🐔🦆Free registration asm.org/webinars/journ…

📢We're looking for a technician (full-time) with strong backround in protein biochemistry to join our lab @uni_muenster #SoN Learn more and apply here jobs-sf.ukmuenster.de/job/UKM-Techni…

'TRIM28 is a target for paramyxovirus V proteins' - the major project from Gauthier Lieber while he was a PhD student in my lab is now available as a preprint: biorxiv.org/content/10.110…

I’m excited to share our latest research from @musser_lab , published today in @Nature. Using two-color 3D MINFLUX, we directly visualized nuclear import and export events through transport-active nuclear pores. nature.com/articles/s4158…

Europe needs a sustainably funded influenza research and response network - especially in the light of H5N1 and current developments in the US. Read our commentary in The Lancet ID: thelancet.com/journals/lanin… With @wendybarclay11, @MarionKoopmans and many other colleagues.

Nicht verpassen: Am Freitag (3. Januar) ist Virologe Christian Drosten zu Gast bei @JungNaiv. Wir sprechen u.a. über die letzte und nächste Pandemie. Ab 14:30 Uhr LIVE youtu.be/av2Hax3Bg1U Habt ihr Fragen an Christian? Her damit!

I’m pleased to share that we FINALLY submitted our latest manuscript on SARS-CoV-2 cryptic lineages and what they tell us about the origins of COVID-19. This was a ton of work. medrxiv.org/cgi/content/sh… 1/

@florian_krammer You should have tried Bahn today around Hamburg/Hannover 🙏👏👍

Frankfurt is one of the most inefficient and unfriendly airports I have visited so far. Usually an unpleasant experience and no exception today.

Students and scientists from ZMBH have joined today's rally in Stuttgart against the de facto decline of the basic funding of universities and for a revision of the State's 2026-2030 Higher Education Financing Agreement III

We are looking to recruit a postdoctoral researcher to work in my group in the Institut Pasteur (Paris), a great place to learn new techniques and establish collaborations. More information here: research.pasteur.fr/en/job/postdoc… If you know someone interested, please share the link.

Across France, people have taken to the streets to protest against road rage, after a car driver intentionally killed a cyclist last week. In 1973, protests in the Netherlands sparked a 50-year long Dutch focus on traffic safety for cyclists.

We're happy to present our latest preprint, where we used cryoET to study tick-borne flavivirus replication in human cells and mouse brains! #cryoEM #virology biorxiv.org/content/10.110…

My commentary on the closure of @VectorBase. Join me in rallying for its sustainable continuation. Comment, repost, and circulate. Let’s ensure this vital resource remains accessible for our global #VectorBiology research community.

The plot thickens: @CDCgov says a close contact of the Missouri #H5 #birdflu case was sick at the same time but wasn't tested. Not clear why that info wasn't shared Thurs during an hour-long press briefing when CDC said Missouri was looking like a "one-off" case. statnews.com/2024/09/13/h5n…

Great opportunity for an ERC interested in #onehealth, #Zoonosis, and #Virology! @unibern @MCIDBern ohws.prospective.ch/public/v1/jobs…

Exciting times at the 9th International #Influenza Meeting in Münster lnkd.in/exSJcMhu Jens presented our computational strategy to prioritize DIPs for novel antiviral treatment design. @ @biofadialnaji @janbaumbach @cosybio_UHH We are excellent @unihh Stay tuned!

De novo design of SARS-CoV-2 main protease inhibitors with characteristic binding modes dlvr.it/TCvVqr