EngeLab

26 posts

EngeLab

EngeLab

@lab_enge

The Enge lab pursues projects focusing on clonal evolution, gene regulation and cell interaction in cancer using novel single-cell multiomics methodology.

Karolinska Institutet Katılım Nisan 2021
57 Takip Edilen40 Takipçiler
EngeLab retweetledi
Björn Reinius
Björn Reinius@BReinius·
Excited to have published our work on #SEQURNA, a next-generation RNase inhibitor transforming #scRNAseq & other applications. ➡️Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq 🚀 🌕 nature.com/articles/s4146… 🧵…
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PeterK
PeterK@KharchenkoLab·
Happy to see our work with Jimmie Ye's lab on coordinated variation of different cell types in healthy and diseased individuals published! At the core of it is the scITD tool for tensor decomposition, rotation and interpretation strategy. Great effort by @J_E_Mitchel et al.!
Nature Biotechnology@NatureBiotech

Coordinated, multicellular patterns of transcriptional variation that stratify patient cohorts are revealed by tensor decomposition go.nature.com/47ARizC

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EngeLab@lab_enge·
Great to be part of this collaboration with @baryawno and @KharchenkoLab among others! Joint single-cell WGS/mRNA seq is an important tool to understand evolutionary processes in tumors!
Karolinska Institutet@karolinskainst

Transformation of fetal Schwann cell precursors (SCPs) may represent one possible mechanism of tumour initiation in #neuroblastoma with chromosome 17 aberrations as a characteristic element. New KI study published in Molecular Cancer @BioMedCentral. doi.org/10.1186/s12943…

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Cira Lab
Cira Lab@TheCiraLab·
Wrists sore from pipetting? Check out our preprint on “Surface Patterned Omniphobic Tiles (SPOTs): a versatile platform for scalable liquid handling”. biorxiv.org/content/10.110…
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EngeLab@lab_enge·
@Jeff_Mold @PaoloGallipoli @SepidehSheybani @AlexanderDent6 Yeah those are all very cool! Notably using sc as just another (important) tool rather than “sequence 2M cells and see what sticks”. The challenge is to move away from a highly controlled model system and still derive knowledge from the experiment.
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Felix Horns
Felix Horns@FelixHorns·
Want to sequence RNA from cells without killing them or deliver RNA programs from cell to cell? Today in Cell, we present RNA exporters, which package and secrete cellular RNA, for non-destructively monitoring cell dynamics by sequencing and delivering RNA authors.elsevier.com/sd/article/S00…
Felix Horns tweet media
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Element Biosciences
Element Biosciences@ElemBio·
Introducing a $200 genome on the AVITI™ Sequencing System, available today. We’re driving down costs and redefining what a benchtop sequencer can do. Element empowers labs everywhere to produce their own high-quality data. Read our press release: prnewswire.com/news-releases/… #jpm2023
Element Biosciences tweet media
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Arjun Raj
Arjun Raj@arjunrajlab·
Is there any software that combines crappiness with indispensability like Adobe?
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EngeLab
EngeLab@lab_enge·
@LarsMHolmgren Thank you for the invitation, and for a great conference day!
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