
RTOG 1112 finally out! Sorafenib +/- SBRT in HCC. Congrats to @ldawsonmd & team. Brief summary here & some of my thoughts. Short thread 🧵. 1/
Laura Dawson
1.3K posts

@ldawsonmd
Radiation oncologist. Prof. & Chair Dept. Rad. Oncology. U of Toronto. Princess Margaret Cancer Centre. Liver cancer. ASTRO Past President. Tweets are my own.

RTOG 1112 finally out! Sorafenib +/- SBRT in HCC. Congrats to @ldawsonmd & team. Brief summary here & some of my thoughts. Short thread 🧵. 1/



🎥NEW President's Corner Member Spotlight: Alejandro Berlin, MD, MSc ASTRO President Neha Vapiwala, MD, FASTRO, interviews Alejandro Berlin, MD, MS, professor at the University of Toronto and Medical Director of the Cancer Digital Intelligence Program at Princess Margaret Hospital. Watch on YouTube: ow.ly/bXnc50YSCk1 Watch on ASTRO's website: ow.ly/mW1C50YSCk0 @NehaVapiwala @aleberlin2


1/7 🧵 New in @LancetOncology: we built a Delphi consensus on primary endpoints for MDT trials in oligometastatic cancer — because the endpoints we've been using were designed for drugs, not for ablation. On behalf of the EORTC–ESTRO OligoCare consortium.

You'll recognize a few names on this author list! @AgrawalAmiya @CJTsaiMDPhD & team show us that palliative RT is undergoing a major evolution ⚡️—from symptom relief ➡️ a multidisciplinary, precision-driven discipline with a dedicated workflow! What’s changing? 🧠 Team-based care is central: #radonc + physicists + advanced practice RTTs + NPs + supportive care = more personalized, efficient & safer treatment decisions ⏱️ Rapid-access clinics ✔️ Referrals seen within ~24 hrs ✔️ “One-stop” visits: consult + simulation same day ✔️ Fast-track pathways deliver RT within hours for pain crises 🚀 Workflow innovation ✔️ Simulation-free RT using recent diagnostic CTs ✔️ Single-fraction treatments (8–20 Gy) ✔️ Fewer hospital visits + faster symptom relief 🎯 Better technology = better care ✔️ IMRT/VMAT + SBRT improve conformality ✔️ Reduce toxicity to normal tissues ✔️ Enable safer re-irradiation & hypofractionation 👩⚕️ Advanced providers expand capacity ✔️ pAPRTs: contouring, planning, workflow leadership ✔️ NPs: toxicity management, follow-up, continuity ✔️ Earlier detection of complications + improved experience 🔬 Not just care—innovation hub ✔️ Trials reducing skeletal events with prophylactic RT ✔️ Survival gains (e.g., proton CSI in leptomeningeal disease) 🚨Bottom line: Palliative RT is no longer just supportive care—it’s fast, adaptive, multidisciplinary, and increasingly impactful on outcomes and quality of life 💡 @ASTRO_org advancesradonc.org/article/S2452-…


















The full course schedule and faculty list are now out for the Clinical & Experimental #Radiobiology Course! Don't miss this opportunity to learn from top experts and connect with peers in radiation oncology. @MKoritzinsky 👉Register by April 10: uoft.me/utdro-radbio20…



Powerful advocacy in action 💙 @lauren_henke sharing the stage with an incredible patient, Luke—amplifying the importance of colorectal cancer screening and trusting your gut when something feels off. Early detection saves lives. #CRC #CancerPrevention bit.ly/3Pqt4mR