Tonythetiger

837 posts

Tonythetiger

Tonythetiger

@linanthony89732

Katılım Nisan 2023
8 Takip Edilen124 Takipçiler
Tonythetiger
Tonythetiger@linanthony89732·
@spontonic They will present that data at ASCO. silevertinib has a very short DOR in the C797s population that's why the company pivoted to first line non classical egfr mutation.
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Spontonic
Spontonic@spontonic·
$BDTX Has anyone seen or heard any commentary on inhibition of de novo brain mets? TIA, if so.
Spontonic@spontonic

@KMIA320 @Miljenkoz ORR, C797S cohort, n=33. Everyone else was focused on first line. At EV ~ 95m, I was more interested in that intracranial cohort in experienced patients and if there's any bzz about inhibition of de novo CNS mets.

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Balder
Balder@Balder13946731·
OpenAI建立了一个私募基金来促进其AI在更多行业的使用。就是AI版的循环融资,以促进OpenAI可以占据更多ToB行业。 OpenAI一定要尽全力去提高AI取代人力的能力,一旦可以赚钱,资本的逻辑就会推着整个风车转起来。
Bloomberg@business

OpenAI will acquire a consulting company to contribute to a new private equity-backed joint venture to help drive adoption of its artificial intelligence software across more businesses bloomberg.com/news/articles/…

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Qiuyao Mo
Qiuyao Mo@MoQiuyao201314·
香港艺人黄秋生真是一个有骨气的人。即便被中共打压得那么严重,五年都无戏可拍,但依然坚守自己的价值观和底线。2026年4月中旬,黄秋生接受“绿豆”专访时,当被问到如果现在还能在香港拍戏,是否还想拍?他回答“一切只能向前看,但是他很庆幸自己还能像人一样直立行走”。光这表态就比很多艺人要强了。
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Tonythetiger
Tonythetiger@linanthony89732·
@wenqinwei @3596675596com 但是你忘了2020前 华尔街秃鹰狙击特斯拉不是上海工厂给力特斯拉会被Bill Gate 这些人搞死。 马斯克也知道进入中国市场的代价是什么,中国也需要强力去推动新能源车产业,本来是双赢你只会指责抄袭窃取。商人难道不知道这是中国模式吗? 既然知道为什么还选择joint venture。
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孤绝星辰
孤绝星辰@wenqinwei·
@3596675596com 但是你忘了,中国的任何产业和产品都是跟在人家屁股后面,用抄袭和窃取等方式实现所谓的“弯道超车”!当初没有特斯拉带动中国的电动汽车供应链和充电桩发展,能有今天的中国电车产业吗?
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沙漠之狐 埃尔温·隆美尔
沙漠之狐 埃尔温·隆美尔@3596675596com·
说一个残酷的事实 欧美日韩在新能源汽车领域,在技术、品控、体验方面,全方面落后于中国新能源汽车 美系新能源独苗特斯拉,哪怕花钱给懂车帝充值,都没能改变特斯拉销量下滑的处境
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Biotech Pharma Investor
$BHVN Anything better out there for IgAN?? I realize data are early but mechanism of action and PoC data from 1st cases are pretty compelling. BHVN cheap based on just IgAN indication. Add to this the rest of the pipeline. What is the bear thesis here??
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Tonythetiger
Tonythetiger@linanthony89732·
@Stmkrs @_financeken @RayneWothbaum I would finish phase 2 obesity data for T-alpha sell it to lily. Sell kv7 program to Pfizer NOW given Pfizer been selling their Nurtec. Sell or shelf all other programs. Use the money execute on degrader platform. Focus on rare disease for accelerated approval. Instant rerate
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Tonythetiger
Tonythetiger@linanthony89732·
@Stmkrs @_financeken @RayneWothbaum Do the math yourself. After a strong 30 patient phase1/2 data with clean safety. One 220 patient Phase 3 trial will cost ~200 B. invest into the raise at that point knowing chance of further dilution is zero will give much much higher market cap than now.
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Tonythetiger
Tonythetiger@linanthony89732·
@Stmkrs @_financeken @RayneWothbaum If management could acknowledge we are not in QE era and partner out all other drugs except their degrader platform. Then Yes IGN degrader is worth 2B market cap alone with strong phase 1 data and mechanism. If investors will get diluted every 6 months then hard to justify.
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Tonythetiger
Tonythetiger@linanthony89732·
@jacksonhinkle This is so funny. Shouldn't Isreal be paying? Why force Arab countries to pay ?
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Jackson Hinkle 🇺🇸
Jackson Hinkle 🇺🇸@jacksonhinkle·
🇺🇸🇮🇷 Trump claims he will likely force Arab countries to pay Iran reparations for war damages Iran estimates its war losses at $270 BILLION
Jackson Hinkle 🇺🇸 tweet mediaJackson Hinkle 🇺🇸 tweet media
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Tonythetiger
Tonythetiger@linanthony89732·
@aus_mini 这种进监狱会被其他囚犯虐待到死, 狱警会睁一只眼闭一只眼。
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AusMini
AusMini@aus_mini·
💥重磅:马斯克呼吁立即处决前FedEx司机Tanner Horner! 这名罪犯已承认谋杀7岁女孩Athena Strand。他开车撞到女孩后,惊慌失措,将她绑架上车,强迫她脱衣服,女孩哭喊“妈妈”时仍被残忍勒死。 法庭播放行车记录仪音频时,陪审员当场落泪。 这种恶魔必须公开处决!绝不能让纳税人养他一辈子。 正义必须迅捷而严厉! #AthenaStrand #死刑 #正义
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Tonythetiger
Tonythetiger@linanthony89732·
@ZacharyBrennan maybe they should have worked with FDA and run a good trial like RVMD.
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Zach Brennan
Zach Brennan@ZacharyBrennan·
$REPL CEO tells me they’re not going to appeal the 2nd CRL but will try to work with FDA - for now, commercial team/other layoffs, cash runway til Q1 of next year, stock price -75% from Fri endpoints.news/replimune-look…
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Brian Shields
Brian Shields@MrPug94·
@drsprs Sushil Patel looks very confident in this video 🙈
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Dr. S
Dr. S@drsprs·
After the original CRL last year, $REPL CEO Patel went on BiotechTV and appeared surprised at the rejection. Now with the new FDA releasing CRL PDFs immediately you can tell he was lying in this interview. No position but this is prime shitco biotech behavior. And people wonder why old timer biotech investors are so cynical and suspicious. Because you have to be to make it.
BiotechTV@BiotechTV

𝐂𝐨𝐦𝐩𝐚𝐧𝐲 𝐍𝐞𝐰𝐬: After receiving a CRL for its RP1 oncolytic immunotherapy yesterday, the CEO of @Replimune walks us through the program's timeline and history, and what this might mean for its future. $REPL Full video: biotechtv.com/post/sushil-pa…

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Tonythetiger
Tonythetiger@linanthony89732·
@HenryMorgan_X 美國要站在道德高點裝清高就會礙手礙腳。 epstein 在牢裡自殺這種事情發生在美國大家覺得是有大佬掩蓋真相, 若在中國沒人覺得什麼大不了,肯定是他背後的勢力應該垮了才會死。
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HenryMorgan
HenryMorgan@HenryMorgan_X·
为什么我他妈的越来越觉得美国蠢得无药可救、傻逼到集体脑死亡? 中国把美国所有主流社交App、网站一刀切全禁,连根毛都不准飘进来;可中国的抖音、微信、小红书、TikTok却在美国大杀四方、为所欲为、渗透到底。 外国人在中国连举个牌子、喊句口号都不行,敢拉横幅直接被铁拳砸烂、消失;可中国人跑到美国,堂而皇之地拉横幅、堵路、游行、骂特朗普、骂美国、骂白人,警察还得站边儿给他们当保镖,生怕伤了他们一根“言论自由”的汗毛!这他妈的叫什么“民主包容”? 这根本就是中国把西方民主国家的天真和傻逼当成了单向核武器! 中国一边把高墙筑成铁桶把自己护得密不透风,一边却在你的地盘上肆无忌惮地放火、投毒、搞渗透、挖墙脚、培养第五纵队!世界上哪有这么不要脸的好事儿? 中国这是在明目张胆地利用你的开放,把你当免费战场、免费靶子、免费傻逼!美国还在那儿装什么高贵、玩什么对等?继续当这个千年大傻逼? 为什么美国不直接抄中国作业——对等封杀、对等驱逐、对等铁拳、对等把他们的App和人全部赶出去? 再这么“灯塔”下去,美国早晚被中国玩到亡国灭种,还在那儿自我感动“自由的代价”呢?你再不学着狠一点,就等着被活活玩死!!
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Tonythetiger
Tonythetiger@linanthony89732·
@sohfangwei @siaxares 當代價是他的親友被美軍炸死, 他也重傷殘廢他就會覺得直接離開伊朗就好, 何必讓美國解放伊朗
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方伟|Allen Zeng
方伟|Allen Zeng@sohfangwei·
今晚美东时间8点,如果伊朗不开放霍尔木兹海峡,川普誓言炸毁伊朗全国的电厂和桥梁,把伊朗打回石器时代。 Siaxares سیاکسارِس @siaxares 是一位在伊朗境内的X博主,显然是高科技人士,是一位博士和AI 訓練師與提示工程師(Prompt Engineer),他今天发出如下贴文,非常建议大家看看: 作為一名在伊朗全國網路完全斷線期間,透過Starlink維持連線的伊朗人,我想全力證實川普總統剛才所說的話: 「伊朗人民想要自由。他們生活在一個你們完全無法理解的世界裡。」 47年來,我的民族在伊斯蘭共和國的統治下,承受了系統性的酷刑、強姦、謀殺、羞辱、焦慮、壓迫與悲痛。這是一段漫長而折磨人的苦難,期間不時被殘酷的高峰打斷——如一月的抗議、大規模處決,以及現在的戰爭。 外界根本不知道這些恐怖的規模和深度。只有當這個邪惡政權最終倒台時,全部真相才會傾瀉而出,其程度之深、數量之多,將震驚全人類。 我們現在已經到了這樣一個地步:只要能擺脫這個政權,幾乎沒有任何代價是太高的。因為讓它繼續掌權的代價,是無限的、和更高的。 如果你正在讀這段文字,卻無法理解為什麼有伊朗人會因為自己的國家在戰爭中失敗、被轟炸而感到欣慰……我很羨慕你,因为你從未經歷過我們所經歷的一切。你從未看過你的同胞、朋友、家人和所愛之人幾乎每天都在遭受酷刑、強姦或殺害,而且持續了半個多世紀。你從未見過一個國家被如此緩慢而殘忍地窒息。 我們試過所有能想到的辦法:大規模抗議、異議、和平改革、談判——一切都試過了。但政權的回答永遠只有子彈、絞架和更多的恐怖。 現在,在距離川普最後通牒不到24小時之際,我在伊朗境內懷著沉重的心情寫下這些: 無論接下來發生什麼——只要这个伊朗可以存活,這個政權可以消失——伊朗人民都會對結果感到高興。不論代價多大。 因為讓這個政權繼續存在的代價更高,對我們許多人來說,死亡本身都比在這場噩夢中再多活一天來得更好。 這就是大多數伊朗人的真實心聲——這是一個常常沒有網路、沒有平台、沒有發聲機會的民族的聲音。 世界很快就會明白,為什麼我們會說: 為了自由,可以付出任何代價。為了結束這邪惡,可以付出任何代價。
方伟|Allen Zeng tweet media
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Tonythetiger
Tonythetiger@linanthony89732·
@JDVance_News question is why are these people using their own lives to protect this regime ?
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JD Vance News Commentary
JD Vance News Commentary@JDVance_News·
🚨 #BREAKING: Iran is now using children as human shields around power plants and bridges — hoping to protect their military targets from U.S. strikes. This is pure evil! The same regime that screams “Death to America” is willing to sacrifice its own kids to shield its weapons. President Trump made it clear: A whole civilization may die tonight… but after 47 years of extortion, corruption, and death, the Iranian people might finally be freed. No more hiding behind children. No more playing games with human lives. The regime is run by vile animals. America will not be blackmailed by terrorists using kids as shields. Pray for the innocent. Pray for the fall of this evil regime 🇺🇸 #USA #IranWar #Trump
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Night Owl Biotech Research Group
Night Owl Biotech Research Group@NightOwlBiotech·
Remember, this is not investment advice. We cannot be certain SLNO analyst consensus revenue estimates are credible
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Night Owl Biotech Research Group
Night Owl Biotech Research Group@NightOwlBiotech·
$SLNO M&A EV of $2.44B as multiples of analyst consensus v. 27 peer M&A trxs. Our records indicate SLNO's exit multiples is the lowest since 1/1/13 (o/c analyst consensus may not be credible). $NBIX closed @ 3.1X FY29 (Year 4) consensus & acq SLNO for 1.7X. Accretive? $XBI $IBB
Night Owl Biotech Research Group tweet media
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Tonythetiger
Tonythetiger@linanthony89732·
@semodough If there’s zero safety concerns do you really think the board will sell the company that cheap ?
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dough
dough@semodough·
$SLNO Cantor implied value of $2.9B is above our 1x U.S. peak sales of ~$2.0B. We'd value the stock at roughly ~$90 if we just included in the U.S. opportunity. This implies a 35% market penetration (prior to factoring in any discontinuation rates) vs. the ~10% the company is at today, <1 year into the launch.
dough@semodough

$SLNO - cantor unsure if another bidder will come forward here; on one end the valuation is on the lower side, but on the other we expect several biopharma companies have been tracking this launch closely over the last year since it took place.

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0xliuyi
0xliuyi@liuyi8881·
@_FORAB 川普估计这辈子都想不到伊朗这边态度会这么硬,头铁小王子
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AB Kuai.Dong
AB Kuai.Dong@_FORAB·
特朗普这次没骗我们,双方确实在和谈,促成临时停火协议。但伊朗,拒绝将霍尔木兹海峡开放,作为停火协议的一部分。
AB Kuai.Dong tweet media
Meguro-ku, Tokyo 🇯🇵 中文
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Tonythetiger
Tonythetiger@linanthony89732·
@hanking66 問題是神權教士真的在乎伊朗經濟崩盤嗎? 塔利班都不在乎四處打游擊後來又把阿富汗打了回來。 美國沒有一個強力的代理人,阿富汗事件重演只是早晚問題。
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美股仙人
美股仙人@hanking66·
我说一个反常识的:99%能停战,而且可以不达成协议,继续封海峡。伊朗没有理由拒绝,特朗普差点损失两个飞行员,没必要继续冒风险。至于后面的协议,慢慢聊…退一万步,聊崩了继续打好了,都歇一口气对两边都好。你说油价?伊朗睁一只眼闭一只眼,你能知道通过多少艘?油价不会再上去了。成年人的世界没有输赢,只有双赢。 看看我说的对不对。 Discord在主页,buy the dip,长期持有。
BRICS News@BRICSinfo

JUST IN: 🇺🇸🇮🇷 United States and Iran discuss terms for a 45-day ceasefire that could lead to a permanent end to the war, Axios reports.

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Balder
Balder@Balder13946731·
由于Agent和Vibe Coding的发展,今年正式迎来个人项目的超级大发展,GitHub上新建项目的速度是去年的14倍,到明年,一年在GitHub上创建的项目就会超过过去所有年份的总和。 这就是为什么star数量的历史记录会被一次次刷新以及Anthropic正在dominant的原因。这是真正意义上的生产力革命爆发。 更简单的Coding不是减少了程序员的数量,而是让更多程序员创造更多的项目了。
Balder tweet media
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