I actually used Northern blots with radioactive probes.
Lior Pachter@lpachter
Yeah, well, it turns out grandma figured out all of the analysis methods for single-cell RNA-seq. 1/
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Edoardo Marcora
1.3K posts
Edoardo Marcora
@marcora
Neuroscientist, Geneticist/Genomicist and Computational Biologist
New York, NY Katılım Mart 2008
342 Takip Edilen269 Takipçiler
So true... if you "spaghetti bolonnaise" run as fast as you can! :)
Mambo Italiano@mamboitaliano__
The famous, very Italian chef Gino D’Acampo, who became a TV celebrity in the United Kingdom and a hugely popular influencer, explains the secrets of “bolognese” 🍝🇮🇹
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Edoardo Marcora retweetledi
Incredible that it was only 66 years from the first controlled, powered flight to landing on the Moon!
Wonder of Science@wonderofscience
These two photographs are separated by only 66 years.
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Edoardo Marcora retweetledi
Edoardo Marcora retweetledi
Double foot jump into the crocs…I’m done! 🤣🤣🤣🤣
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Edoardo Marcora retweetledi
@anand_mt @lpachter Putting data in a blackbox and asking a machine to do your job because you only bothered to learn how to use Microsoft Excel is the end of science in my opinion. GraphPad and illiteracy in statistical data analysis amongst biomedical researchers has already done enough damage.
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Edoardo Marcora retweetledi
Bionmi is amazing but from what I can tell it facilitates *running* complex data analysis with ease, which is a very different thing from *doing* analysis, whether poorly or well, with difficulty or with ease.
Anand Mayakonda 🕉️@anand_mt
@KexinHuang5 We are using this already in the lab and it’s extremely useful. Especially for our colleagues with no bioinformatic skills, they’re able to do complex data analysis with ease. Would be happy to test it to the limits.
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Edoardo Marcora retweetledi
@lpachter The prompt in the bionmi promotional video says "analyze these data and generate hypotheses". How can scientific analysis be done without a purpose/research question, let alone expertise in bioinformatics? Else, how would you judge the quality of the results and explain them?
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I always thought hand dexterity was the last ability left for humans to excel at and thus protect us from AI-driven unemployment... I was colossally wrong evidently. We are f@&?*d!!! Especially now that we are putting AI in every modern warfare (drones, robots, missiles, cyber).
Sovey@SoveyX
AI is gonna take your job and your girl.
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Highly recommended for any biomedical research scientist/data analyst interested in moving beyond statistical associations and nil-hypothesis significance testing/p-values.
Richard McElreath 🐈⬛@rlmcelreath
Statistical Rethinking 2026 is done: 20 new lectures emphasizing logical & critical statistical workflow, from basics of probability to causal inference to reliable computation to sensitivity. It's all free, made just for you. Lecture list & links: #calendar--topical-outline" target="_blank" rel="nofollow noopener">github.com/rmcelreath/sta…
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Edoardo Marcora retweetledi
Failure to understand that the fundamental principle of Mendelian randomization (MR) is of gene-environment equivalence contributes to the flood of nonsense MR papers that are appearing; Shah Ebrahim, Gib Hemani and I explain why in this short commentary. journals.plos.org/plosmedicine/a…
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Edoardo Marcora retweetledi
A One-Page Primer on: Statistical Power from @carlislerainey carlislerainey.com/blog/2025-08-3…
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Edoardo Marcora retweetledi
I don’t like the Wikipedia definition of Bayesian statistics. The Merriam-Webster definition is much better!
statmodeling.stat.columbia.edu/2026/03/19/i-d…
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