Max Lam

📚 Our findings contribute to a deeper understanding of schizophrenia biology and pave the way for more targeted therapies and interventions. Stay tuned for updates on our cognitive genomics research! #Schizophrenia #Pleiotropy #MedRxiv #NIMH

🔬 Our new results dissociate forebrain and hindbrain neurodevelopmental processes, and implicate translation initiation factors in schizophrenia pathophysiology for the first time.

🧬 New preprint alert! Our latest manuscript on MedRxiv investigates the complex pleiotropic genetic landscape of schizophrenia, cognitive function and educational attainment uncovering 768 significant loci – 159 of which are novel. medrxiv.org/content/10.110… @ToddLencz

We are looking forward to 2024 WCPG in Singapore (15th-19th Oct). In the words of our 2024 Program Chairs, "These are exciting times in psychiatric genetics." Want to learn more? Check out the 2024 invitation to attend: ispg.net/wcpg-2024-invi… #psychiatry #genetics

@Jimmy_Lee_CK @KeaneLim Thank you to the Phenomics team at the Institute of Mental Health, Singapore! @Jimmy_Lee_CK @KeaneLim Tweetorial to follow soon!

Deconstructing the genetic architecture of treatment-resistant schizop... sciencedirect.com/science/articl… @maxzylam @KeaneLim

We are recruiting! DM if you are interested in doing research for precision medicine!

🤩 OUT TODAY @NatureGenet 📰 The Singapore National Precision Medicine Strategy 👩🏾‍🤝‍👨🏽 John C. Chambers, E. Shyong Tai, Patrick Tan and team 👇🏿🇸🇬🧬👇🏿 go.nature.com/3ZZb186

Pleased to announce the launch of: polygenicembryo.org The website of the Polygenic Embryo ELSI Research (PEER) Group (1/5)

Our latest preprint: a novel cross-ancestry fine-mapping method with much improved power and calibration. A collaboration with @kaiyuan1990 @RyanLongchamps @AFPopgen @getian107 @ChiayenChen @YenFengLin @bmneale @dalygene @PGCgenetics among others! medrxiv.org/content/10.110…

@normacyyyyyy @molpsychiatry Congratulations!

Glad to share this manuscript doi.org/10.1038/s41380… which is finally out in @molpsychiatry. Previous studies identified immune gene dysregulations in the brains of patients with several major brain disorders. (1/7)

@SherifMorris @NatureComms Here’s the link nature.com/articles/s4146….

@maxzylam @NatureComms Congrats! Is there a link to the manuscript or did I miss it?

New manuscript @NatureComms! We leveraged data from 19 cognitive GWAS to disentangle biological mechanisms underlying psychopathology (17 psychiatric GWAS). Some updates from the previous tweetorial! (1/8)

A big thank you and shout out to @ToddLencz @ChiayenChen @getian107 @hailianghuang for their valuable insights and help on this effort!

The results might provide insights into the potential of nootropic agents targeting specific biological mechanisms to alleviate functional disability within psychopathology. (8/8)