Cam McDonald-Hyman, MD PhD

Previously shared: Adoptive transfer of regulatory T cells can treat murine inflammatory disorders, but their efficacy in human disease have been variable. Here, Cameron McDonald-Hyman @mdphd10 et al. @UMNews find human Tregs treated with ACC1 inhibitor during ex vivo expansion enhances mitochondrial fusion/function, Treg function, & treatment in a chronic graft-versus-host disease model: doi.org/10.1172/JCI182… The figure depicts the effects of mitochondrial fusion in the absence of ACC1 inhibition, which enhanced Treg metabolic and suppressive function. Mitochondria (red/orange); vimentin (green); nuclei (blue). #GVHD

Very exciting to see this out in @jclinicalinvest while I’m enjoying #ASH2025 @ASH_hematology! Two of my favorite images from the paper! 👏👏

Adoptive transfer of regulatory T cells can treat murine inflammatory disorders, but their efficacy in human disease have been variable. Here, Cameron McDonald-Hyman @mdphd10 et al. @UMNews find human Tregs treated with ACC1 inhibitor during ex vivo expansion enhances mitochondrial fusion/function, Treg function, & treatment in a chronic graft-versus-host disease model: doi.org/10.1172/JCI182… The figure depicts the effects of mitochondrial fusion in the absence of ACC1 inhibition, which enhanced Treg metabolic and suppressive function. Mitochondria (red/orange); vimentin (green); nuclei (blue). #GVHD

If you’re interested in #Treg #mitochondria #metabolism #GVHD and/or cool imaging techniques courtesy of @MichaelLDustin @ewoudcompeer, check out our in press preview in @jclinicalinvest ! jci.org/articles/view/… @CFI_UMN @UMNews @umnmedschool

Today’s the day! 🎉 Join us for Dr. Sakeen Kashem’s special seminar at 9am in 1-125 CCRB. Learn about how the immune & nervous systems intersect to shape itch, pain, and aging. See you there!

A reminder: you can support @RSCRCF thru @mfca_now Tackle Cancer and enjoy @CRAVEamerica at same time! This month…stop in and have the “Shaver Special” and support Mn cancer community!

@MrJamesMay @dieworkwear @dieworkwear you must listen to @MrJamesMay!

@dieworkwear W123 is one of the best-built cars in history, and they age well. Probably the equivalent of a jacket you could name.

starting to think that buying a home in a walkable neighborhood is simply not attainable, so i've been looking at vintage cars. do car nerds have opinions on these? — Mercedes-Benz W123 — Toyota Land Cruiser 60 — Mercedes-Benz 300TD — Mercedes-Benz W113 Pagoda SL

Today, Stuart Scott would have been 60 years old. In honor of his birthday, we'd love to celebrate and donate $19.65 to the Stuart Scott Memorial Cancer Research Fund! Click the link to make a difference today. donate.v.org/campaign/70674…

“It may not save my life. It may save my children’s lives. It may save someone you love.” – Jim Valvano

👏🏻👏🏻👏🏻

Dominos will continue to fall

Oh my gosh, who could have seen this coming?? Right, everyone in academia…

As we speak, scientisists across the country (including myself) are trying to to take care of simple administrative tasks related to the grants that we have recieved from the National Institutes of Health... 1/n

Congratulations to Lukas D. Wartman GVHD Achievement Award recipient @sghmd of @RoswellPark. #Tandem25

The University of Minnesota leads the way in medical research: 700 NIH-funded projects, including advancing organ transplants, cancer treatments, and Parkinson’s therapies are now at risk. Cutting NIH funding threatens life-saving research and the future of medical innovation.

Dr. Punita Grover @UMNews showing ⬆️ chronic #GVHD with #PTCy/siro/MMF vs PTCy/tac/MMF in a sequential phase II well matched myeloablaive study setting ⚡️#Tandem25

Science is key to the US's success but this government's intention to dramatically reduce the part of the federal grants that go to the university (in addition to the researchers; the "indirects") is like removing the unseen roots of a tree & expecting it to continue to flourish.

#MedTwitter, I worry we missed the boat on scientific communication. If we did a better job of explaining what we do and how we do it, half the country wouldn’t be so happy about defunding us right now.

@RonDePinho Yes!

Wow, I didn’t know there were so many experts on academic research and indirect costs! We researchers are so lucky to have such an incredible group looking out for our finances!