Michael Botta
615 posts

Michael Botta
@michaelbotta
Co-founder, @sesamecare, a top-ranked health tech company. Formerly: @McKinsey, PhD @HMSHCP. Enemy of online gambling and helicopters. Otro jíbaro luchando.
New York | 🇵🇷 Katılım Şubat 2011
5.2K Takip Edilen1.5K Takipçiler
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@NotThatTomGreen No joke this is also what I settled on as the best possible replacement.
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Announcing a rematch for next weekend would genuinely make up for the Ricochet/Leon Slater match being pulled.
A legendary match.
Isaiah Noah 3.0 💿@Noah__Isaiah
A Common thing that Editors do In this community Is just get so bored and edit random shit for shits and giggles (↓)
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@Noahpinion Does she think people would be against this? Why! It's awesome!
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Michael Botta retweetledi
Michael Botta retweetledi

Some brief thoughts on Mythos
We’ve known this was coming for a long time. At least, we *should* have. Extremely effective software vulnerability discovery was clearly coming to anybody paying attention.
It has also been clear that all AI policy so far has been made and executed with training wheels. It was always clear that, sometime soon, the training wheels would come off.
The training wheels aren’t fully off just yet—this model is being kept under lock and key, and Anthropic does not seem inclined to release Mythos preview to the public anytime soon, if ever. The training wheels will be off when these capabilities are fully diffused in ways centralized actors cannot control. It is inevitable that this will happen. The point is not to argue about whether we should “ban open source” or similarly unrealistic notions. The point is to harden the world for this new reality.
I applaud Anthropic—and I especially applaud @logangraham—for doing so. But their efforts alone are not close to enough. Project Glasswing—a partnership with Anthropic and other companies—seems nice, but unsurprisingly it lacks uniform frontier lab participation.
It would probably be ideal, for our national cyberdefense, if the federal government were not trying to destroy Anthropic and eliminate their models from government systems. If anything, the government should be trying to work more closely with Anthropic. As a side note, I hope Anthropic is working with state and local government entities on cyber vulnerability discovery, since many of our adversaries know that state and local is America’s soft underbelly in so many ways.
In any event, the Mythos news should lay bare how stupid and counter-productive the Department of War’s feud with Anthropic really is. As someone who suspected all this was coming (not from inside knowledge but from it being ~obvious), that probably explains why I have had such a strong reaction to that feud. It’s this senseless distraction just at the time that the training wheels are coming off. I hope the two parties can resolve their differences now, for the sake of the country, but I am not hopeful.
I do want to call out, however, the numerous political and career civil servants in the Trump Admin who do get these issues, know how stupid the Ant-DoW stuff is, and want to work with the frontier labs like adults. I wish you all utmost success.
I find myself inclined to end on some positive notes. Mythos appears to be—according to Anthropic at least—“the most aligned” model Anthropic has ever trained. We are approaching superhuman capabilities in some domains, and yet alignment is getting better rather than worse. That’s not nothing. I know some of you think the model is faking its alignment, or aware when its alignment is being tested. I don’t have a good answer.
Finally, there is this: Mythos was made by an American company, and like most successful American companies, it has a vested interest in maintaining order and peace, and it is investing substantial resources in mitigating the risks of its technological progress, as I expect most of the American labs would. This is cause for optimism: The incentives of capitalism are working.
The training wheels are coming off, but at least we are the ones removing them, as opposed to our enemies. Perhaps we can be the first to learn to bike for real. The first step would be to get beyond all the low-fidelity, under-specified, pimply little fights of AI policy’s prepubescent era. That goes for me too.
“What hath God wrought,” wrote the first telegram. What, indeed. In this case, the answer is still up to us.
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Greatest babyface performer Japan has seen since Tanahashi retired
Alysa Liu Updates@AlysaUpdates
Alysa Liu's Stateside program at the Stars On Ice show in Osaka, Japan x.com/alysaliumedia/…
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@nateliason @steipete Not impressed by minimax so far. Hearing better things about GLM 5.1. Hoping to see agent specific improvements out of gpt 5.4 though - would rather keep my personal data on shore.
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I have full faith that @steipete is going to make GPT in OpenClaw amazing...
But the switch from Opus has been tough today.
Any other models people are liking that are worth trying? Minimax 2.7?
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@brianthomsontv @SarahLongwell25 I’d bet on LBJ for that actually.
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@michaelbotta @SarahLongwell25 Definitely the first to call people fuckin bastards.
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@SarahLongwell25 Pretty sure he's the first US President to lead off Easter Sunday with a message of "Praise Be to Allah."
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@Shpigford Openrouter paid API key is primary and I'm experimenting with different models all week.
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Michael Botta retweetledi

New study has strengthened link between infectious mono and Multiple Sclerosis. By analyzing 2 decades of health records, researchers found people who contracted mono as teenagers or adults were 3x more likely to develop MS later vs those who didn’t
neurology.org/doi/10.1212/WN…
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@Sempervive Mike I'd advise against referring to your wife this way.
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I think about and quote this interview weekly. Love it.
Rob Naylor@NINaylor
Probably my favorite interview ever 🤘
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Personally I don’t think he should have read that woman’s journal.
Oscar Willis@oscarswillis
Here's Deontay Wilder sharing the most insane story you've ever heard told on national TV
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pharma did this. say thank you.
Samuel Hume@DrSamuelBHume
How outcomes in relapsed/refractory multiple myeloma changed, from 1986 to 2026
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Michael Botta retweetledi

Contrary to popular belief, we are trying to cure cancer!
Samuel Hume@DrSamuelBHume
How outcomes in relapsed/refractory multiple myeloma changed, from 1986 to 2026
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@PhilKlay @RegisHighSchool Hope you got to pick your side in advance for this one!
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@michaelbotta @RegisHighSchool Does the current U.S. conflict with Iran meet the criteria of a just war?
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Heading to @RegisHighSchool to debate the war in Iran this morning. It will be moderated by my old high school debate coach, Eric DiMichele.
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