michael ryan

Biology doesn’t change at the border. Autism risk does not depend on the flag printed on a vaccine schedule. What matters is exposure biology: •antigen load •timing •cumulative dose •developmental windows Those are measured by large birth-cohort and registry studies that follow children from birth using medical records — the right design for outcomes diagnosed years later. Arguing about schedule labels is a distraction. Causation lives in mechanisms, dose–response, and replication — not semantics.

On this day in 1973, Carole King played a free concert on The Great Lawn in Central Park with an estimated audience of between 70-100k. The Parks Department handed out garbage bags to the crowd, who famously cleaned up after themselves.

And Australia says????

Now More Than Ever, We Must Continue Not Thinking About It

#DuringCOVID is today.

I try to stay as professional as possible on here, but the recent spate of tweets I've seen bemoaning that 'things just haven't been the same since 2020' or similar and then utterly ignoring the ongoing impact of SARS-CoV-2 infuriates me. Denial and ignorance in equal measure.

People Able To Ignore Airborne Pathogens Still Unable To Ignore Masks

For anyone who’s ever faced a personal challenge, it doesn’t get much better than the 'Six Minutes' speech in VISION QUEST. This scene wasn’t in the 1979 novel by Terry Davis. Elmo's monologue was written specifically for the film by screenwriter Darryl Ponicsan (THE LAST DETAIL, TAPS). Actor J. C. Quinn absolutely knocks it out of the park here. If you’d like to support the @FMJDiary project, you can bid on an original poster below. I signed and inscribed it with Elmo’s iconic line: “It ain't the six minutes... it's what happens in that six minutes.” ebay.us/m/p2kYOc

@outbreakupdates "Failure by Design" ☠️☣️☠️

South Australian Health Minister Blair Boyer faced intense backlash and criticism from anti-vaxxers on social media after posting a photo of himself receiving a COVID-19 booster shot on Facebook. Source: archive.md/JJF2I

@PhillipAdams_1 Me three!

Me too Mike

Association of long-COVID with major adverse cardiovascular events and mortality: a real-world data cohort study 🚨Still not shocked: L0NGC0VID patients are 4.5× more likely to suffer heart attacks, strokes & deadly clots, and 53% more likely to die? WAKE-UP! ➡️Large retrospective cohort study used TriNetX real-world electronic health records (~118 million US patients) to assess long COVID’s impact on cardiovascular outcomes, ➡️ Adults (≥18 years) diagnosed with COVID-19 (2020–2023) were included. The long-COVID group (diagnosed 3–6 months post-infection) was compared with matched non-long-COVID controls after 1:1 propensity-score matching (86,122 per group, balanced on demographics, comorbidities, vaccines, etc), ➡️ Primary outcomes: major adverse cardiovascular events (MACE: coronary artery disease, stroke, myocarditis, heart failure, pulmonary embolism) and all-cause mortality, with follow-up starting 90 days post-index date (mean ~3 years), ➡️Long-COVID patients showed markedly higher MACE risk (HR 4.48, 95% CI 3.95–5.07), driven by coronary artery disease (HR 6.48), stroke (HR 3.46), and pulmonary embolism (HR 4.35), ➡️All-cause mortality was also elevated (HR 1.53, 95% CI 1.38–1.69), ➡️Risks remained consistent across 1- and 3-year follow-ups, age, sex, race, BMI, hospitalization status, antiviral use, and SARS-CoV-2 variant periods (Alpha/Delta/Omicron), ➡️Mechanisms discussed include ACE2-mediated myocardial injury, endothelial damage, chronic inflammation, and autonomic dysfunction, ➡️Pre-existing cardiovascular conditions were excluded to isolate long-COVID effects, ‼️So, patients with long COVID face a substantially elevated risk of major adverse cardiovascular events and all-cause mortality compared to those without long COVID, underscoring the need for vigilant long-term cardiovascular monitoring in this population, “This multicenter real-world cohort study demonstrates that patients with long COVID have a significantly higher risk of major adverse cardiovascular events (MACE) and all-cause mortality compared with those without long COVID” #AvoidSars2 #AvoidReinfections #YouOnlyHaveOneHeart link.springer.com/content/pdf/10…

@MatthewModine He did rewrite the camera lighting book with Barry Lyndon. There had been nothing like it ever before-I don’t think any other film has looked so good since.

I love them all, but I think THE SHINING and FULL METAL JACKET might be more accessible - especially for those who’ve never experienced a Kubrick film before.

We are in #India for a pandemic exercise and workshop with @icmr_nie . I have travelled to most parts of India, and each time, I am awestruck by the weight of history and culture of this ancient civilisation.

This:

I am going to repost this everyday, until I get one of the following to support @AmberWoods100 #EpsteinFiles @UnrealBluegrass @morgfair @hwinkler4real @StephenKing @Chris_Meloni @StellaParton Please consider looking at Amber's hard work & supporting her via your large platform.

Just one of the many things we do to "live our lives". We just do it without getting sick. A visit to the ROM, back in March. #WorldMaskWeek #PassTheMask

Tried to get Flotilla activists to mask up on way home but… if hubby had been in this mission he woulda been the only one. As head of delegation Australia he refused to attend festivities on East coast as totally no mitigations considered. When activist priorities collide.

Hear hear.

Zelenskyy: Russians just destroyed the Chornobyl museum — built one month ago. Crazy assholes. We strike military targets — weapons production, energy that funds their army. Russia hits museums, schools, apartments. 1/

ZELENSKYY: We attack military targets in Russia, or their energy, which they sell to fund war. Russians deliberately target civilian objects: museums, schools, apartments. They destroyed this Chornobyl museum that we built for 40th anniversary just one month ago. Crazy assholes.