
Michael Mignano
8.2K posts

Michael Mignano
@mignano
General Partner @USV. Co-Founder Anchor (acquired by Spotify) and @OboeLabs.
Katılım Temmuz 2008
702 Takip Edilen44.8K Takipçiler
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Fred Wilson is one of the greatest VCs of all time. He is also my new partner at @USV and I'm lucky to say that. We've known each other for years, but becoming partners felt like a reason to get to know him even better.
So a few weeks ago, we walked around Union Square and caught up about what @fredwilson has learned over nearly 40 years of VC, how AI may be making the profession obsolete, how to build an investment thesis, why he believes the Knicks will win the NBA title this year, and a few of his long held grudges.
Here's a video of that conversation, set at Union Square, Madman Espresso, the USV office, and Leon's on Broadway.
Chapters:
3:22 - That time Fred wrecked Mike on Twitter
6:01 - Pre-Internet VC in NYC
9:50 - Early Internet Investing and Raising for Flatiron Partners
11:59 - The Dot-com Crash Killed Fred’s First Firm
14:28 - Fred’s Grudge Against Coffee Shop
16:35 - How to Pick the Right Team at Right Time
18:28 - AVC blog, Gawker’s Nick Denton, TypePad.com
20:44 - Jim Kramer invented Tweeting
21:46 - Why Fred Bet on Twitter Early
23:39 - Building Agents on Claude Code and Tasklet
26:20 - Claude Mythos and Doomerism
27:27 - The Original USV Thesis
29:19 - Network Effects and Brad’s Thesis
31:29 - Coinbase: Thesis, Investment, Outcome
33:18 - Investing in Decentralized AI
34:59 - Open Source AI
36:55 - AI Kill Zone: Legal AI is Dead, Energy Investments
42:37 - USV Agents Will Replace Its Partners
47:00 - Are VC’s building themselves out of a job?
48:30 - Leon’s, NYC’s New Tech Watering Hole
50:52 - Generative Art
53:18 - SOLIENNE: AI Artist trained by Kristi Coronado
54:25 - What About AI Scares Fred
55:40 - Societal Backlash to AI
58:10 - Advice to Early Career VCs: There’s More Risk in Not Doing Deals
1:00:48 - Fred’s Biggest Regrets: Saying No Because of Price
1:04:17 - Fred’s Bold Prediction for the Knicks and the Mets
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@AndyJScott github.com/mmignano/sheet…
this is part of it but i've been going much deeper as of late
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@mignano You just asking it in a chat for recommendations or built a different kind of tool?
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@AlanaDLevin i prob shouldn't say
dont think its a good idea for me to give stock advice :)
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@mignano What are the best stocks it's picked so far (and its short thesis for each)?
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@blauyourmind @mignano @trydrip Good day Mr Michael
Are you aware of a platform in base called bankr?
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@tereza_tizkova @azzabazazz @_patrickogrady @commonwarexyz My guess the router would get rewarded for picking the right model. Perhaps via speed, efficiency etc.
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@PossibltyResult smart. i agree that there is a huge opportunity for open source and user-centric harnesses. we've been thinking about this space quite a bit at usv.
semi-related:
x.com/mignano/status…
Michael Mignano@mignano
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@mignano IMHO routing will be achieved by task-based agentic bounty markets dynamically repricing in near real time.
Needs High Throughput Blockchain to work but I know some MIT media lab affiliated wunderkinds cooking it up atop @_patrickogrady’s @commonwarexyz
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@amywumartin @OpenRouter exactly. impressive product and company!
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@yb_effect oh that's a great call. i like the insurance idea a lot...
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@yb_effect yea i think the most obvious way is to charge a margin on the tokens but that feels like not a great place to be. i like the idea of rewarding performance somehow and attaching revenue to that.
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reminds me of the classic crypto chain routing dilemma / DEX aggregators. but of course there's just a lot more variability in the tasks for general agents.
if models do continue to commoditize AND people are okay with non-frontier models for the long tail of tasks, then I think the most interesting thing to think about is how the model routers (agent orchestrators or whatever you want to call them) get paid.
my guess is a hybrid of how many tokens each intent cost as well as how successful the task was done (time, accuracy, efficiency, etc). this is great because now most people don't have to worry about subscriptions and can simply monitor the allowances we're giving.
forget normal consumers, most people in tech have stopped trying to keep up with all the OS models out there. i myself have subscriptions to gpt, claude, and grok and already feel overwhelmed
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@mattcynamon it depends. in some areas, building your own model gives you massive cost advantages with respect to training and inference. and then over time, you get user preference data that gives you a very strong model advantage as you scale.
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