Michael White

Join our team! We’re #hiring for a head of our condensate platform. The right candidate will be an experienced scientist who can lead multidisciplinary teams focused on target evaluation, assay development & project prosecution. Apply here: jobs.lever.co/fazemed/bd615b…

Understanding the biologic features that help cells stay organized through phase separation. ow.ly/5JZb30s4KRS @NatureChemistry @TanjaMittag @PappulabWashU

We're now 2 yrs into the decisive decade. Emissions should be in an unprecedented fall, instead we're seeing the 2nd biggest rise ever recorded. We're wasting invaluable time pretending we can solve this crisis without treating it like a crisis. World leaders are still in denial.

Our 4th JMB Special Issue of 2021 was "Phase Separation in Biology and Disease: The Next Chapter" edited by @kriwacki @StJudeStructBio and @SElbaumG @GC_CUNY. To date, this compelling collection is our most downloaded and cited JMB issue of 2021! bit.ly/3jbPIfV

We’re so excited to announce the release of our paper, "Phase Separation mediates NUP98 Fusion Oncoprotein Leukemic Transformation" in Cancer Discovery @CD_AACR today!(cancerdiscovery.aacrjournals.org/content/early/…)! (thread)

Join us on Thursdays for seminars by @hofmann_hagen and @RibackLab (aka @SuperSciJew)! New attendees can sign-up at: IDPseminars.com!

Happy to share our work with Thea K. Schulze, @rcrehuet & @LindorffLarsen on modeling liquid-liquid phase behavior of instrinsically disordered proteins, now out in #PNAS. doi.org/10.1073/pnas.2… @MSCActions #BRAINSTRUC @uni_copenhagen #LinderstrømLang

Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates pnas.org/content/118/37…

Happy to share our thoughts science.org/doi/10.1126/sc… on an exciting new mechanism for regulating the size of biomolecular condensates discovered by @Seydouxlab: science.org/doi/10.1126/sc…

@schmittwitt_ A note about grades and F32. I had this point when I applied first to NINDS. However, if you read closely, you need not use your undergrad grades. Your grad grades are sufficient for F32. So don’t include them and they will hold no weight. Not included in sub to NIGMS, funded.

@CharlotteFare If you open a file, then go to file open you can open another in the same “instance” to move the structs relative to one another you can click in the lower right to toggle between “three button” modes (need a mouse) then you can click on an individual struct and move it

Full version is out elifesciences.org/articles/67176 We take great pleasure in introducing a physical chemistry inspired theory in condensates biophysics. #LLPS #RuleBasedModeling @lesloew

This study showcases both beautiful theory and experiments, quantifying the forces needed for condensates to pull in DNA!

The solubility product extends the buffering concept to heterotypic biomolecular condensates elifesciences.org/articles/67176

A phase transition enhances the catalytic activity of SARM1, an NAD(+) glycohydrolase involved in neurodegeneration dlvr.it/S2jxSq

Accurate model of liquid-liquid phase behaviour of intrinsically-disordered proteins from data-driven optimization of single-chain ... biorxiv.org/cgi/content/sh… #biorxiv_biophys