Which cytokine, primarily secreted by macrophages, acts as the chief mediator of the acute-phase response and induces hepatic C-reactive protein?
A) IL-2
B) IL-6
C) IL-10
D) IL-12
@MoarSahitoPTI Thromboxane A2 (from COX1) promotes clotting while prostacyclin (COX2) inhibits clotting.
Selective COX-2 inhibition decreases prostacyclin (the good guy) but leaves Thromboxane A2 (the bad guy) unchecked => thereby multiplying the risk of intravascular clotting
Kolkata, West Bengal: A doctor has posted on social media stating that any individual visiting him for a consultation and saying 'Jai Shri Ram' will receive an instant discount of ₹500
Doctor P.K. Hazra says, "... I have been observing free patient care for a long time, and I always had the intention to support the BJP mentally. I believe in supporting them... There is nothing unethical or political slogan-based in it; it is purely a service initiative... My consultation fee earlier was ₹2000 in my clinic (not in a hospital). First, I reduced it to ₹1500 to help people before elections, and yesterday I decided to reduce it further. Now, anyone who shows this will be charged ₹1000 for consultation..."
@modernHealthMe Shingle
Reactivation of latent Varicella zoster from a single dorsal root ganglion => following a single dermatome, not crossing the midline
Acyclovir 800 x 5 times x 7 days
Acetaminophen & prednisolone if needed
Calamine lotion
Comfortable clothing
@modernHealthMe Methotrexate
90% is excreted unchanged in urine => monitor KFT to ensure this is not affected
10% is metabolized by liver => monitor LFT
Causes Bone marrow suppression => monitor CBC
Combine with folic acid to avoid folate deficiency symptoms
A patient with rheumatoid arthritis shows this deformity.
Best drug to prevent progression?
A. Methotrexate
B. Hydroxychloroquine
C. Sulfasalazine
D. Leflunomide