Michael V Holmes (he/him)

LDL Cholesterol Saves Lives! What a fantastic example of cherry picking! Yes this person is right, in ELDERLY people, all cause mortality is greater amongst those with low LDL cholesterol… but WHY? And why didn’t he bring up all cause mortality with LDL levels amongst those who are not elderly? Oh because he doesn’t like that data. This is a textbook example of reverse causality. LDL Cholesterol is not protecting people from disease, but rather people with wasting diseases like cancer are more likely to be resistant to wasting if LDL is not low, indicating that they are not emaciated. But if we zoom out of the elderly and look at lifelong LDL exposure & the risk of mortality, it tells a very different story. Lifelong LDL cholesterol exposure has a LINEAR association with increased mortality, especially from cardiovascular disease (CVD) (PMIDs: 23083789, 38241044, & 30694319). In fact, reduced LDL exposure early in life throughout adulthood can reduce the chance of mortality from CVD by up to 3 times! Gee I wonder why he didn’t mention that. Additionally, the unremarkable results from many statin trials comes from the fact that often these are prescribed after a CVD event or later in life when someone has already done significant damage to their blood vessels. But even with that being the case we do see a clinically significant benefit in lowering the risk of mortality with statin use (PMIDs: 36233511 & 37368941). That said, statins can have some side effects & are not appropriate for everyone & you should speak to a cardiologist about your options if you have high LDL But this is a textbook example of carnivore zealots trying to do f***ery with science & giving you a 3rd of the info to try to trick you into believing their nonsense