Simon Hill MSc, BSc

8 years and 400+ episodes hosting The Proof podcast Here’s 10 episodes I recommend listening to if you’re interested in improving your health.

NEW JAMA cardiology paper - PROMISE randomised clinical trial looking at plaque volume and major cardiovascular events. jamanetwork.com/journals/jamac… H/T Dr Dan Soffer.

@theproof @VinnieTortorich This is the type of response when the actual evidence is contrary to their desired belief.

@SBakerMD And what evidence is there that this reduction is clinically meaningful Shawn?

Lp(a) is now considered a very important driver of cardiovascular disease. We are told it is genetic and that a “healthy diet” can’t affect it! However several studies, including this randomized controlled trial, show that decreasing carbs and increasing saturated fat can in fact drive down Lp(a) sciencedirect.com/science/articl…

@withered_haze @VinnieTortorich So I can create a story depending on what I choose to see outside?

@theproof @VinnieTortorich *looks outside* *highest ever life expectancy* God dayum those seed oils be mighty powerful

The Best evidence? Sure, walk outside and look around...

@NutritionMadeS3 Thanks @NutritionMadeS3

Great contribution setting this up Simon!

@VinnieTortorich Can you provide the best evidence you have that seed oils are inherently unhealthy? Love to see it.

This is the part where we will disagree... Eggs are one of the healthiest foods you can put in your mouth. I can show you a couple of studies, but that won't matter, because you will come back at me with something from Dr Greger (never finished his degree) saying that even one egg per week will clog arteries. Or, maybe Dr Alo who likes to make it up as he goes. Maybe a Harvard study, but Willet sold out a long time ago. Eating a whole plant diet is not the worst thing you can do... You will be lacking in a few amino acids along with vitamins, but doable. Eating a vegan diet full of sugars and grains is where the real problem comes in. I don't have a horse in this race, I just want people to be healthy. Processed foods (Which we agree, are not healthy) full of processed sugar, grains and seed oils are the problem.

@DeathlyHarvest @TyBealPhD Is it an assumption? Or a fact?

@theproof @TyBealPhD I already know. He's a fraud.

The new U.S. Dietary Guidelines sparked a huge debate in nutrition. Christopher Gardner, Ty Beal, and I unpack what the science actually says about ultra-processed foods, protein, and where most people are getting nutrition wrong. For the full show notes head to: theproof.com/the-dietary-gu…

@DeathlyHarvest @TyBealPhD can answer that!

@theproof Who funds ty Beal? beef and dairy?

@paulsaladinomd ??

In our latest study we show that resistance-bands work 💪 These are a great alternative to use when you are travelling, can’t get to the gym, tight on time, etc. Resistance-bands + creatine (3 or 5 grams/day) work a bit better 😊 #creatine sciencedirect.com/science/articl…

Why Does Politics Decide What Americans Should Eat? | Chistopher Gardner and Ty Beal | EP#409 youtube.com/shorts/9FXbrl4… ⁦@TyBealPhD⁩ ⁦@GardnerPhD⁩

@paulsaladinomd @eatlineage By coconut nectar do you mean coconut sugar - granulated dry product? Or is the manufacturer legitimately using a syrup?

The sweetness in our bar comes from two real-food ingredients: raw organic honey (glyphosate free honey from @eatlineage) and organic coconut nectar. The total amount of sugar in the whole bar is less than one tablespoon of honey. The label says “added sugar" b/c the FDA requires honey and coconut nectar to be listed as added sugars when used in a multi-ingredient product, even though they are minimally processed whole-food sweeteners with their own natural nutrient profiles. On their own, neither would carry that label. The regulation is a classification rule, not a judgment on quality. Raw honey contains trace enzymes, antioxidants, and amino acids. Coconut nectar is lower on the glycemic index than table sugar and retains minerals from the coconut palm. Neither behaves in your body the way refined cane sugar does. These are real food forms of sugar. Want some PMIDs to back up that statement? 2951092 19817641 36834366 P.S. Is it a little ironic that this post is from a guy named Danish and my last name is Saladino? I think so!

@realDaveFeldman @Heartflow Will the Cleerly CMO still be on your papers involving this cohort study?

Yes, specifically, retraction due to CLEERLY anomalies of the analysis they provided us, and their repeated decline to do a quality control check. @Heartflow has been an entirely different experience— they’ve helped ensure operational blinding, and are more than happy to run reanalyses for quality control* (*Regardless, their dataset does, in fact, match the same patterns of the other analyses within our study, and all those outside our study — ie, regressors, 0 CAC = lower progression, etc)

@softboygirl @drmatthewnagra @nicknorwitz @raphaels7 @realDaveFeldman @AdrianSotoMota Totally. Not sure they’re picking up what everyone is putting down.

@theproof @drmatthewnagra @nicknorwitz @raphaels7 @realDaveFeldman @AdrianSotoMota Simon, you will note the criticisms in that video elicit a lot of arm waving from the study team with no substance. Inviting you to debate is not an answer to the lack of scientific rigor displayed in the April 7th paper. Retraction of paper doesn’t take away those issues.

I haven’t yet verified the validity of his criticisms, however, they are verifiable and don’t come with the usual ad hominem attacks - refreshing! Looking forward to @realDaveFeldman @nicknorwitz @AdrianSotoMota rebuttal

@paulsaladinomd @BobCobb69363325 Coconut nectar is sugar. It is evaporated into a syrup or crystallized into granules (coconut sugar), containing primarily sucrose, along with some glucose and fructose.

@BobCobb69363325 Nah, USDA requires honey to be listed as "added sugar." Lineage bar only sweetened with organic, glyphosate-free honey, organic strawberries, wild blueberries and coconut nectar.

Which would you choose?

I’m digging my heels in? Interesting. Let me see if I can have you understand my position. First, I don’t find your answer of “I don’t know what happened” satisfactory with regards to how Cleerly got unblinded scans. This error comes from your team - there is no ‘I’ in team. Work it out, communicate it and take responsibility. Second, you guys continue to parade around with unpublished data from a single arm extremely short term study as if it’s earth shattering information. If there was less hype, less rushing and more care these issues may not be surfacing. If digging my heels in is refraining from engaging further until your group properly takes responsibility as adult men… then consider them dug!!

Completely made up nonsense. Charts were direct R output. @AdrianSotoMota can provide code. Simon in particular is embarrassing himself. Critics are contorting themselves in pretzels to avoid the fact the original CLEERLY data are upended - not a high risk group - ApoB doesn’t predict progression. We’ve offered to discuss/debate. In fact Simon has a standing offer for expenses paid trip to Vegas to join @realDaveFeldman in his pod. At this point he’s just shallowing virtue signaling and digging in his heels. Sad.

@caloriesproper2 @KenDBerryMD @paulsaladinomd I eat protein bars so your tweet makes no sense

@theproof @KenDBerryMD @paulsaladinomd ugh x.com/caloriesproper…

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