nopestaja 🧩

@TakeThiamine @DejaRu22 How can you get doxycycline in anticipation of tick bites? And would you really take for every tick bite? I seem to get one a year but they may only be on me for an hour - I check religiously

Actually no. The well-established mechanism is based on decades of cumulative evidence. It’s textbook pharmacology. Doxycycline binds to the 30S ribosomal subunit and blocks aminoacyl-tRNA attachment to the A site, halting translation elongation and protein synthesis. This is the same mechanism for the entire tetracycline class, and Borrelia burgdorferi is well-established as susceptible. I will concede that “a single dose” was too absolute (even though I said “can”). However, a single 200 mg dose is still the official CDC and IDSA guideline recommendation for prophylaxis. I’d opt for 10 days on regardless of how early it was caught. Yes, the study showed more nausea/vomiting in the doxycycline group. That’s a mild, transient side effect for most people. It does not refute efficacy. The trial showed a clear drop in Lyme disease with doxycycline vs. placebo. Subsequent reviews and meta-analyses have reinforced that finding in high-risk scenarios. You advocate for riding out sepsis, so I can’t imagine you’re really concerned about some nausea. There is no reason not to take doxycycline in this case. I’m all for not abusing antibiotics—and they are over-prescribed, and there are many I would never take (especially fluoroquinolones)—but doxycycline is not even close to a dangerous choice here. The upside is huge. The downside is a tummy ache.

@TakeThiamine @PGC1a_RB How long would you need the tick on you to want to get doxy? Over 24 hours?

A single 200 mg dose of doxycycline within 72 hours of removal of a deer tick can save you from a life of Lyme disease. If symptoms appear later, a full 10-day course is still highly effective. The mechanism is well-established. Take the antibiotics.

@AncientMedicin3 @Zedzies Kinda thought your username referred to psychedelics lol. Acupuncture? Herbs?

@mywickedson @Zedzies

The ultimate longevity herb has been hiding in plain site for almost 2 thousand years. Contains the most effective aged glycation end product (AGE) breaker I’ve ever come across in the literature. The new centenarian study found that anti-glycation gene upregulation is amongst the most important factors for organismal life extenstion.

@Brian_Peotter @BowtiedQueenBee I’m not wearing camo, I’m wearing Kuiu dad

Things we would never have under socialism for $500 alex

@Zedzies Gonna keep hiding it?

@AncientMedicin3 @Zedzies Holy shot never knew you were actually versed in ancient medicine. Are you a TCM practitioner?

He Shou Wu holds the clinical properties you mentioned. The medicine Buddha is usually depicted holding Haritaki (Terminalia chebula). In the bowl often depicted next to the Buddha is Amrita, which is a holy medicinal compound but not a single herb. In Tibetan medicine that’s often not just herbs but naturally occurring minerals as well. Aru, Baru and Khyuru, Triphala and/ or Rinchen Rilbu. Tinospora cordifolia is often included in that as are “precious substances” such as gold ash, pearl, silver, coral or lapis lazuli. In Chinese medicine we are thinking along the lines of tonic herbs or “superior herbs” from the Shennong Bencao Jing.

@CChadChampion Louis ck and Joey tribbiani too

im this schizo

A few of you have asked to see a bit more Frog content...

@Vesouw @HNoticer17435 @SolBrah Zero percent chance you drink your daily water through a lifestraw

@HNoticer17435 @SolBrah Well yeah, but it's better to buy a good waterfilter like lifestraw and get best food possible, while growing your own, than to inject yourself with anything.

Dudes that inject testosterone have given up

@JakeSablosky @jspujji can you elaborate on what makes it superior for marketing?

@jspujji I’m a marketer and do not code. I use Claude Code 100% of the time, it is far superior to Cowork. If you think it’s irrelevant, maybe you need to give it a try?

@MBrant75 @codyaims How are you on iOS 18? My X won’t let me update past 16

@codyaims I’m still on the X Try resetting your dictionary If you make enough typos I think it will actually remember them and autofill

I found my 9 year old iPhone X and decided to charge it to test a few things - There's no lag switching between apps / screens - I had zero typos while typing 6x faster. Returning to my "new" phone, I had 7 typos while just writing this post

@mrfroggymuffin @Link_Hodlr420 B-b-but I thought chainlink were the good guys - neofeudalists? I thought the 4IR was all about truth and freedom.

@Milkisloove @VERYKOOLLUKEY In the hippy vegan way or just local and in season?

@VERYKOOLLUKEY One word: macrobiotics

If you want a perfect diet you only need to study three people: Weston A price Raymond Peat Aajonus Vonderplanitz They aren’t right about everything, but the truth lies somewhere here

@StaniKulechov How about you say no, try a (much) smaller amount?

Earlier today, a user attempted to buy AAVE using $50M USDT through the Aave interface. Given the unusually large size of the single order, the Aave interface, like most trading interfaces, warned the user about extraordinary slippage and required confirmation via a checkbox. The user confirmed the warning on their mobile device and proceeded with the swap, accepting the high slippage, which ultimately resulted in receiving only 324 AAVE in return. The transaction could not be moved forward without the user explicitly accepting the risk through the confirmation checkbox. The CoW Swap routers functioned as intended, and the integration followed standard industry practices. However, while the user was able to proceed with the swap, the final outcome was clearly far from optimal. Events like this do occur in DeFi, but the scale of this transaction was significantly larger than what is typically seen in the space. We sympathize with the user and will try to make a contact with the user and we will return $600K in fees collected from the transaction. The key takeaway is that while DeFi should remain open and permissionless, allowing users to perform transactions freely, there are additional guardrails the industry can build to better protect users. Our team will be investigating ways to improve these safeguards going forward.

@LiamCristiano @Alvi19478870 Ttfd makes me feel gross should I trust my gut and take a different form?

@Alvi19478870 It's ok it's just too sulphury for my tastes, and I like the taste of thiamine mono and benfo, so it's probably too sulphury for anyone

To a curious newcomer, I think taurine, benfotiamine, and aspirin, are my top 3 Peaty supplements. Very cheap, very safe; wide mechanism of action, all push the system in the right direction.

@SolBrah I take a walk during my lunch break daily and end up with my best strategies in the process

What is the point of WORKING and being “productive”? To make progress! Many people will take this to mean, work harder and input more stress and control and grinding = more success But that’s NOT the case. You should work hard - for sure. But ALSO realize, that you make more progress when you CHILL - allowing divine intelligence to arrange things for you When you attach yourself to events and STRESS about it, you get in your own way It literally affects the energetic matrix around you - which is tied to your success It is literally more logical and productive to CHILL. So chill out on life my friends.

@SolBrah You mentioned alternate theories of Kali Yuga timeline/duration. In your opinion when does this one begin and end approximately? Digging the videos recently, they’re really helping shed the virgin doomer mindset, thanks Brah!

New video on the Kali Yuga is live on YouTube - link below

@Helios_Movement Any reason TTFD would make me nauseous?

@TheLinkPanda Squeeze me in needs more frogs

Are you in yet? $LINK

@Zedzies @PGC1a_RB So chicken lamp farther away?

So many people are overdosing on red and near infrared light. High dose = fibroblast death Low dose = collagen production Lower the dose and increase the time. This is more consistent with sunrise/sunset.