Nuri

At last, in print sans "pre-"! Grazie mille to my co-authors/co-conspirators @jcslab at beyond, w/o whom I'd still be stuck on a translation problem! TL;DR: Mtb codon context bias may be baked in to regulate transcription, but I hope you'll give it a read. journals.asm.org/doi/10.1128/mb…

FINALLY! Thanks to the indomitable @JaisinghaniN87 we proudly present the ultimate Mtb cell wall proteome and some surprising-- and exciting-- members: Type VII secretion substrates EsxB & EsxG! 1/n biorxiv.org/cgi/content/sh…

Infinite thanks to @jcslab and the many brilliant/generous collaborators who made this science adventure possible! ✨💕🥲 And thanks, of course, to mycobacteria for being such interesting weirdos.

Hurrah! Announcing the awesome thesis work of @noosly! Or, how synonymously recoding genes in mycobacteria is like Bjork’s “It’s Oh So Quiet”. 1/n biorxiv.org/content/10.110…

New preprint — and a new (to our knowledge) mechanism by which synonymous codons can regulate gene expression! Looking forward to feedback.

Lovely lovely monarchs.

Being done doesn't feel like being done when you've got unfinished manuscript business. But this is a good time as any to say I've had (am still having??) the best time in the best lab @jcslab

Me defending my dissertation this morning (photo credit to the loveliest @LiaParkin):

@pmoyniha Reminds me of this paper. Could there be a relationship to ribosome stalling/mRNA conformation change at certain codon pairs? pubmed.ncbi.nlm.nih.gov/31858614/

This is conceptually insane. nature.com/articles/s4146…

Me editing my latest paper draft @OpenAcademics @AcademicChatter #academictwitter

Check out our, @GeneWeiLiLab @julianstanley_, new paper showing that a large fraction of RNA molecules in bacteria are fragments of canonical full-length mRNAs with consequences for differential RNA-seq analysis: doi.org/10.1093/nar/gk…

Synonymous sequence changes are not necessarily silent, and here they can have life-or-death consequences. Now out in @eLife by former lab members @JIPerlmutter and Jane Meyers. Thanks to editors and reviewers for the constructive and kind review. #annotations" target="_blank" rel="nofollow noopener">elifesciences.org/articles/67686…

Happy to have penned this review on bacterial lipidomics with @JaisinghaniN87! All reviews co-edited with @basktastic for this #lipidtime issue coming soon.... Free access to our paper: sciencedirect.com/science/articl…

🚨I wrote a big piece about how Delta affects the pandemic endgame. Many folks are upset & confused by the last month. Here's an attempt to reset expectations, lay out our goals, map the near-term future, & show how the pandemic ends--which it will. 1/ theatlantic.com/health/archive…

JSeeliger Lab is hiring a postdoc! See official ad below and please help spread the word. Wanted: #microbiology /#biochemistry/chem bio experience and eagerness to explore all things mycobacteria w/ a focus on the cell envelope.

Excited for @BBM today and tomorrow! For fun in mycobacteria visit @jcslab 5-min poster talks: #47 @noolsy - unexpected consequences of gene recoding on expression #58 @LiaParkin - exploring lipid transport functions of a membrane transporter and lipoprotein

'I will do it tomorrow,' said Toad. 'Today I will take life easy.'

Excited to share our first preprint on inhibitors of M. tuberculosis that we characterized using a competitive activity-based protein profiling platform. A long-haul team effort from @jcslab @AldridgeLab @canaanlab and the Cravatt lab. 1/n